ЖКТ и печень — клинические исследования

Advanced Solid Tumors (Such as Gastric Cancer) · Advanced Solid Tumors (Such as Adenocarcinoma at the Gastroesophageal Junction) · Advanced Solid Tumors (Such as Pancreatic Cancer)

Идёт набор NCT07595003

Efficacy, Safety, and Tolerability of 4-MUST, 128 mg Tablets in Chronic Cholecystitis and Biliary Dyskinesia

Фаза III С лечением Россия

Chronic Cholecystitis · Biliary Dyskinesia

Идёт набор NCT05615818

Personalized Medicine for Advanced Biliary Cancer Patients

Фаза III С лечением Бельгия, Франция +1

Biliary Tract Neoplasms

Идёт набор NCT07488611

PROGAIN Trial in Gastric Cancer Surgery

Фаза III С лечением South Korea

Stomach (Gastric) Cancer

Идёт набор NCT07595172

NALIRIFOX+Adebrelimab+PULSAR for Advanced Pancreatic Cancer

Фаза I / Фаза II С лечением Китай

Pancreatic Ductal Adenocarcinoma (PDAC) · Locally Advanced and Metastatic Pancreatic Cancer

Идёт набор NCT05169177

Radio-opaque Contrast Agents for Liver Cancer Targeting With KIM During Radiation Therapy

— Наблюдательное Австралия

Liver Neoplasm

Идёт набор NCT07317076

GT Metabolic Magnet System in Adults With Gastrointestinal Disorders

Без фазы С лечением Канада

Gastric Outlet Obstruction · Small Bowel Obstruction · Superior Mesenteric Artery Syndrome

Идёт набор NCT04106518

Study of Genetic Determinants in Alcoholic Hepatitis and Establishment of a Multicenter Prospective Cohort of Patients With Alcoholic Liver Disease

— Наблюдательное Франция

Alcoholic Liver Disease · Severe Alcoholic Hepatitis · Alcoholic Cirrhosis

Идёт набор NCT07431723

Creation of Compression Anastomosis Using the GT Metabolic Magnet System

Без фазы С лечением Чили, Италия

Anastomosis, Functional · Colorectal

Идёт набор NCT05884255

An Open-label Phase 3 Study of Lutetium (177Lu) Oxodotreotide Injection in Subjects With Advanced Gastrointestinal Pancreatic Neuroendocrine Tumors.

Фаза III С лечением Китай

Advanced Gastroenteropancreatic Neuroendocrine Tumor

Идёт набор NCT07144683

Anastomotic Leakage After Colorectal Surgery.

— Наблюдательное Египет

Anastomotic Leak · Colorectal Cancer · Diverticulitis

Набор скоро начнётся NCT07359456

Testing Ivonescimab in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancers Without Liver Metastases

Фаза II С лечением Франция

Metastatic Colorectal Cancer

Идёт набор NCT05184790

LEARN: Learning Environment for Artificial Intelligence in Radiotherapy New Technology

— Наблюдательное Австралия

Arrhythmias, Cardiac · Breast Cancer · Prostatic Cancer

Идёт набор NCT06904378

ONT01 and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal Adenocarcinoma

Фаза I / Фаза II С лечением США

Metastatic Pancreatic Ductal Adenocarcinoma

Идёт набор NCT06414902

18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer

Фаза I С лечением США

Esophageal Cancer

Идёт набор NCT05404230

Prevention of Oxaliplatin-induced Nerve Damage in the Body's Extremities

Без фазы С лечением Дания

Peripheral Neuropathy · Colorectal Cancer

Набор скоро начнётся NCT07524699

A Study About Remote and Local Liver Surgery

Без фазы С лечением Китай

Liver Diseases

Набор скоро начнётся NCT07490405

Long-term Efficacy and Safety of LSD Versus TIPS for Cirrhotic Portal Hypertension Bleeding and Hypersplenism

— Наблюдательное Китай

Liver Cirrhosis

Идёт набор NCT06769113

A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy

Фаза II С лечением Китай

Esophageal Cancer

Набор скоро начнётся NCT07581574

Neoadjuvant SHR-A1811 and SHR-A1701 for Potentially Immunotherapy-Sensitive GC or GEJ Adenocarcinoma

Фаза I С лечением Китай

Gastric or Gastroesophageal Junction Adenocarcinoma

Идёт набор NCT07420426

Instant Message-delivered Personalised Acceptance and Commitment Therapy (IMPACT) for Neuropsychiatric Symptoms in Persons With Mild Cognitive Impairment

Без фазы С лечением Гонконг

Mild Cognitive Impairment (MCI)

Идёт набор NCT04731272

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

Фаза II С лечением США

Cystic Fibrosis · Pancreatic Insufficiency · Abnormal Glucose Tolerance

Набор скоро начнётся NCT07592819

A Trial Using Transcriptomic Signatures to Personalize Neoadjuvant Chemotherapy (NAC) for Patients With Resectable Borderline Pancreatic Adenocarcinoma (PDAC)

Без фазы С лечением —

Pancreas Adenocarcinoma (MSI-H) · Pancreatic Cancer Resectable

Идёт набор NCT07377656

Strengthening HPV Immunization Through EPI Leveraged Delivery

Фаза II С лечением Ghana

HPV Vaccine

Набор скоро начнётся NCT07591597

A Multicenter, Phase Ib/II Clinical Trial to Evaluate the Efficacy and Safety of Concurrent Combination Therapy of S-531011 Plus Fruquintinib or S-531011 Plus Fruquintinib Plus Pembrolizumab in Patients With MSS/pMMR Colorectal Cancer

Фаза I / Фаза II С лечением —

Metastatic Colorectal Neoplasms · Microsatellite Stable / Proficient Mismatch Repair Colorectal Cancer

Набор по приглашению NCT05788029

Comparing Laparoscopic and Open Pancreaticoduodenectomy for Nonpancreatic Periampullary Adenocarcinomas

Без фазы С лечением Китай

Periampullary Adenocarcinoma

Идёт набор NCT01514045

The Gastric Cancer Foundation: A Gastric Cancer Registry

— Наблюдательное США

Gastric Cancer

Идёт набор NCT06824064

Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer

Фаза II С лечением США, Пуэрто-Рико +1

Metastatic Colorectal Cancer · Advanced Colorectal Cancer

Идёт набор NCT07495111

Prophylactic PS Placement to Prevent Pancreatitis After Endoscopic Transpapillary GPC for Cholelithiasis With Concomitant Choledocholithiasis

Без фазы С лечением Китай

Cholelithiasis Associated With Common Bile Duct Stones

Идёт набор NCT06682481

Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function

— Наблюдательное Швейцария

Obesity, Childhood · Type 2 Diabetes Mellitus in Obese

Набор скоро начнётся NCT07593638

Plasma Exchange Half-dose and Extracorporeal Detoxification for ACLF

Без фазы С лечением Португалия

Acute on Chronic Liver Failure (ACLF)

Идёт набор NCT05947838

A Prospective Feasibility Study Using ctDNA to Tailor Neoadjuvant Chemotherapy for Patients With Colorectal or Appendiceal Adenocarcinoma

Без фазы С лечением США

Appendiceal Adenocarcinoma · Colorectal

Идёт набор NCT07461610

Stool Analysis After Sleeve Gastrectomy vs Gastric Bypass

— Наблюдательное Египет

Morbid Obesity

Идёт набор NCT06288711

Novel Telemedicine-Delivered Prolonged Exposure Therapy for Treating PTSD in Individuals With OUD

Без фазы С лечением США

Opioid Use Disorder · Posttraumatic Stress Disorder

Набор скоро начнётся NCT07585786

Effect of LSD on Renal Function in Cirrhosis Patients With Portal Hypertension Bleeding (2-Year Follow-Up)

— Наблюдательное —

Cirrhosis, Liver · Splenectomy; Status · Renal Function Abnormal

Идёт набор NCT05727020

Volatile Organic Compound Assessment in Pancreatic Ductal Adenocarcinoma

— Наблюдательное Великобритания

PDAC - Pancreatic Ductal Adenocarcinoma · Pancreatic Cancer

Идёт набор NCT07040228

A Phase Ib/II Clinical Study of Regorafenib Combined With Toripalimab and Albumin-bound Paclitaxel for the Third-line Treatment of Advanced Pancreatic Cancer

Фаза I / Фаза II С лечением Китай

Pancreatic Cancer Metastatic

Набор по приглашению NCT07592013

Effect of Ancestry Supplementation in Subjects With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Без фазы С лечением Мексика

MASLD

Набор по приглашению NCT06463223

HIBOC = Hepatic Imaging Biomarkers in Obese Children

— Наблюдательное Швеция

Elastography · Shear Wave Elastography · Shear Wave Dispersion

Идёт набор NCT07026422

Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT)

Фаза II С лечением Китай

Rectal Malignant Neoplasms

Набор скоро начнётся NCT07581626

Short-Course Online Adaptive Radiotherapy Combined With Chemotherapy, Targeted Therapy and Immunotherapy as Total Neoadjuvant Therapy (TNT) for Locally Advanced Rectal Cancer

Фаза II С лечением Китай

Locally Advanced Rectal Cancer (LARC)

Набор скоро начнётся NCT07594548

Futibatinib With Paclitaxel and Ramucirumab for the Treatment of Locally Advanced or Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Фаза I С лечением США

Clinical Stage II Esophageal Adenocarcinoma AJCC v8 · Clinical Stage III Esophageal Adenocarcinoma AJCC v8 · Clinical Stage III Gastric Cancer AJCC v8

Идёт набор NCT04421820

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

Фаза I / Фаза II С лечением США, Канада +5

Colorectal Cancer · Pancreatic Cancer · Gastric Cancers

Набор скоро начнётся NCT07590336

68Ga-NYM207 PET/CT Imaging in Hepatocellular Carcinoma

Фаза I / Фаза II С лечением Китай

Hepatocellular Carcinoma (HCC)

Идёт набор NCT06649292

SHR-A1904 Compared With Investigator's Choice of Therapy in Claudin18.2 Positive Patitens With Second-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Фаза III С лечением Китай

Second-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Идёт набор NCT07591571

To Evaluate the Preliminary Efficacy of Our Digitally Enhanced CHW-led Intervention in Newly Diagnosed PDAC

Без фазы С лечением США

Pancreatic Cancer, Adult

Набор скоро начнётся NCT07551596

Testing the Combination of Anti-Cancer Drugs, Botensilimab (AGEN1181) and Balstilimab (AGEN2034), After Standard Treatment for Colorectal Cancer, Combat Trial

Фаза II С лечением —

Colorectal Adenocarcinoma · Stage II Colorectal Cancer AJCC v8 · Stage III Colorectal Cancer AJCC v8

Набор скоро начнётся NCT07111130

Restoring Bile Acid Homeostasis Via Lifestyle Adjustments to Prevent the Development of Liver Cancer

Без фазы С лечением Сингапур

Liver Diseases

Идёт набор NCT05698992

Rehabilitation and Recovery for Persons With Esophageal or Gastric Cancer

— Наблюдательное Швеция

Esophageal Cancer · Esophageal Neoplasms · Gastric Cancer

Набор скоро начнётся NCT07591480

Barriers And Facilitators To Clinical Trial Enrollment: A Qualitative Study Of Pancreatic Cancer Patients

— Наблюдательное США

Pancreatic Cancer

Набор скоро начнётся NCT07574502

Transcutaneous Electrical Acustimulation on Postoperative Bowel Function Recovery in Elderly Patients

Без фазы С лечением Китай

Colorectal Cancer (CRC)

Набор скоро начнётся NCT07590284

Sonazoid CEUS for Early HCC Surveillance

Без фазы С лечением Китай

Liver Cirrhosis · Liver Fibrosis

Набор скоро начнётся NCT07138846

A Study Comparing MRG004A Plus Best Supportive Care Versus Placebo and Best Supportive Care in the Treatment of Patients With Advanced Pancreatic Cancer

Фаза III С лечением Китай

Advanced Pancreatic Cancer

Идёт набор NCT05627219

Extending Prostate Genetic Awareness, Navigation, and Delivery: The EXPAND Network

— Наблюдательное США

Metastatic Prostate Carcinoma · Stage IIIB Prostate Cancer AJCC v8 · Stage IIIC Prostate Cancer AJCC v8

Идёт набор NCT06302621

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

Фаза I С лечением США

Advanced Solid Tumor · Unresectable Solid Tumor · Metastatic Solid Tumor

Идёт набор NCT07438106

A Phase II Study of HRS-4642 Combined With AG (Nab-paclitaxel and Gemcitabine) as Conversion Therapy for Locally Advanced Pancreatic Cancer

Фаза II С лечением Китай

Locally Advanced Pancreatic Cancer With KRAS G12D Mutation

Идёт набор NCT06300463

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Фаза II С лечением США

Colorectal Cancer Metastatic · Liver Metastases · Colorectal Cancer

Идёт набор NCT05783375

Accelerating Delivery of rheUmatic Heart Disease Preventive iNterventions in Northern Uganda

Без фазы С лечением Uganda

Rheumatic Heart Disease

Идёт набор NCT07591246

Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid Hypofunction

Без фазы С лечением Египет

Polycystic Ovary Syndrome · Non-Alcoholic Fatty Pancreatic Disease · Subclinical hypothyroïdism

Идёт набор NCT07588854

Correlation Of EUS-SWQ And Liver Fibrosis Pathology In Chronic Liver Disease

— Наблюдательное Китай

Chronic Liver Disease (CLD) · Liver Fibrosis

Набор скоро начнётся NCT07572708

Transcutaneous Electrical Acustimulation (TEA) for the Treatment of Non-Erosive Gastroesophageal Reflux Disease (NERD)

Без фазы С лечением Китай

Non-erosive Reflux Disease (NERD)

Набор скоро начнётся NCT07588568

A Trial of Upadacitinib for Non-responsive Eosinophilic Esophagitis

Фаза II С лечением США

EoE · Eosinophilic Esophagitis · Eosinophilic Esophagitis (EoE)

Идёт набор NCT07280390

Microplastics, Cirrhosis and Portal Hypertension

— Наблюдательное Индия

Cirrhosis · Microplastics · Portal Hypertension Related to Cirrhosis

Идёт набор NCT07401199

Multimodal AI for Predicting Response to Neoadjuvant Immunotherapy in Gastric Cancer (PRISM-GC)

— Наблюдательное Китай

Gastric Cancer (GC) · Locally Advanced Gastric Cancer

Идёт набор NCT06691893

Evaluating the Efficacy of RELiZORB in Managing Exocrine Pancreatic Insufficiency in Tube-fed Pancreatitis Patients

Фаза III С лечением США

Exocrine Pancreatic Insufficiency (EPI) · Pancreatitis

Набор скоро начнётся NCT07590856

A Preliminary Efficacy of SNA028 in Patients With Advanced Colorectal Cancer Positive for GPA33

Ранняя фаза I С лечением Китай

Colorectal Cancer

Идёт набор NCT05402696

St. Paul's Advanced Resection Center Cohort for Colorectal Neoplasia (SPARC-C)

— Наблюдательное США, Канада +1

Colon Adenoma · Colon Polyp · Colon Lesion

Набор скоро начнётся NCT07591493

Adjuvant Trial in Pancreatic Neuroendocrine Tumors

Фаза III С лечением Франция

Pancreatic Neuroendocrine Tumors (pNET) · Pancreatic Neuroendocrine Tumors

Идёт набор NCT06580574

Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers

Фаза II С лечением Китай

Gastric Cancer · Colon Cancer · MSI-H

Набор скоро начнётся NCT07589400

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Characteristics of ACT500 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Complicated With Chronic Hepatitis B

Фаза I С лечением Китай

Metabolic Dysfunction-associated Steatotic Liver Disease · Chronic Hepatitis b

Идёт набор NCT05925309

Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai Portoenterostomy

Без фазы С лечением Китай

Biliary Atresia · Cholangitis · Anti-Bacterial Agents