Instant Message-delivered Personalised Acceptance and Commitment Therapy (IMPACT) for Neuropsychiatric Symptoms in Persons With Mild Cognitive Impairment

Официальное название

Instant Message-delivered Personalised Acceptance and Commitment Therapy (IMPACT) for Neuropsychiatric Symptoms in Persons With Mild Cognitive Impairment: a Mixed Methods Study

Обзор

This study aims to develop an automated instant message-delivered intervention (i.e., EMI) for people with mild cognitive impairment to reduce their NPS, and to investigate the feasibility and effectiveness of the intervention.

Подробное описание

1. Message contents:

The message content library will consist of four parts: 1.orientation, 2. brief mild cognitive impairment education messages, 3. acceptance and commitment therapy messages, 4.booster message. 2. Message delivery

* Regular messages: The messages in the four parts will be sent regularly to each participant. As personalisation is a core process subject to behavioural changes, the timing of the messages will be determined based on participants' preferences. To save labour and increase efficiency, the investigators will develop a message 'scheduler' program. The investigators will pre-set the message scheduler, which will then automatically send out content to the participants according to their preferences. The development of the program is highly useful particularly in cases which participants prefer to receive messages during non-office hours. * Real-time support messages (chat-type): Chat-based support will be given to the participants as an extension of the regular messages. However, the participants will be informed beforehand that the RA will only play a supportive role and will not provide formal care. The number of the chat messages will not be limited, but the real-time support messages will only be provided during working hours on weekdays to limit the RA's workload.

Control Group:

The control group will receive instant messages about mental health management from GovHK website (https://www.gov.hk/en/residents/health/mental/), which is open to the public.

Вмешательства

• Поведенческое automated instant message-guided neuropsychiatric symptoms management
  Participants in intervention group will receive the EMI for 9 weeks. Based on the steps of mobile message development recommended by Abroms, et al., we will develop a message content library and protocol for EMI delivery.
• Поведенческое general mental health management
  Participants in control group will receive the messages for 9 weeks. The control group will receive instant messages about general mental health management from the HKSAR Government website, which is open to the public (https://www.shallwetalk.hk/en/mental-well-being/mental-well-being-is-related-to-you/), with reminder text messages of follow-up surveys.

Первичные конечные точки

• MBI-C scores [Срок оценки: at baseline, 10th week and 24th week]

Вторичные конечные точки (6)

• Depressive symptoms (PHQ-9) [Срок оценки: at baseline, 10th week and 24th week]
• Anxiety symptoms (GAD-7) [Срок оценки: at baseline, 10th week and 24th week]
• Quality of life (EuroQol 5-dimension 5-level questionnaire [EQ-5D-5L]) [Срок оценки: at baseline, 10th week and 24th week]
• Cognitive functions (HK-MoCA) [Срок оценки: at baseline, 10th week and 24th week]
• Acceptance of negative emotions and valued-based actions (AAQ-II) [Срок оценки: at baseline, 10th week and 24th week]
• Subjective Cognitive Decline scale (SCD-9) [Срок оценки: at baseline, 10th week and 24th week]

Критерии участия

Критерии включения

• Community-dwelling adults aged ≥ 50 years
• HK-MoCA score ranged from 18 to 22
• MBI-C ≥7
• SCD-9 ≥3
• IADL =18
• Able to read and communicate in Chinese
• Able to use the text or voice messaging function on a smartphone

Критерии исключения

• Clinical diagnosis of dementia
• Clinical diagnosis of psychiatric disease
• Currently participating in any type of psychological or behavioural intervention for NPSs
• Currently taking psychiatric medication
• Currently receiving acute care or post-acute hospitalization care

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Двойное слепое

Основная цель

Поддерживающая терапия

Центры проведения

Гонконг · 1 центр

• The University of Hong Kong — Гонконг

Публикации

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Идентификаторы

NCT: NCT07420426 · IMPACT2025

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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