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Recruiting NCT06982235

Stone and Laser Therapies Post-Market Study (SALT)

Observational Benign Prostate Hypertrophy(BPH) Renal Calculi Ureteral Stones, Kidney Stones Calculi, Urinary

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Ureteroscope system, Laser system.
Who it may be relevant to
Registry conditions: Benign Prostate Hypertrophy(BPH), Renal Calculi, Ureteral Stones, Kidney Stones, Calculi, Urinary. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Stone and Laser Therapies Post-Market Study

Overview

The objective of the SALT Study is to obtain post-market safety and device performance data for Boston Scientific's Stone and BPH study devices used during a diagnostic and/or therapeutic urinary tract procedure (e.g., transurethral or percutaneous access routes) or benign prostatic hyperplasia (BPH) treatment.

Detailed description

The SALT study is a multi-center, open label, non-randomized, prospective observational study to document on-going post-market safety and device performance data of BSC commercially available study devices that are used in diagnostic and/or therapeutic urinary tract procedures or surgical treatment for BPH.

Enrolled subjects undergoing diagnostic or therapeutic procedures using study devices will be followed for 1 year after the index procedure is complete.

Interventions

  • Device Ureteroscope system
    LithoVue™ Elite Single-Use Digital Flexible Ureteroscope System with intrarenal pressure monitoring
  • Device Laser system
    Pulse™ 120H Holmium Laser System with MOSES™ 2.0 Technology

Primary outcome measures

  • Occurrence of Serious Adverse Events related to BSC study devices [Time frame: From procedure to 12-months after the procedure]
Secondary outcome measures (2)
  • Assess Stone Free Rate in therapeutic Urinary Tract Procedures [Time frame: 21 - 90 days after the procedure]
  • Change in BPH symptoms [Time frame: 6 months after the procedure]

Eligibility criteria

Inclusion criteria

For urinary tract procedure cohort:

  • Subject intends to undergo diagnostic and/or therapeutic urinary tract procedure with qualified BSC device(s)
  • Subject is willing and able to complete all follow-up visits

For BPH cohort:

  • Subject is ≥ 40 years of age
  • Subject with a diagnosis of benign prostatic hyperplasia (BPH) with lower urinary tract symptoms
  • Subject intends to undergo BPH treatment with qualified BSC device(s)
  • Subject is willing and able to complete all follow-up visits

Exclusion criteria

For urinary tract procedure cohort:

  • Subject requires simultaneous surgical treatment for BPH
  • Unwilling or unable to provide consent
  • Any other condition which, in the opinion of the investigator, precludes study participation (e.g., history of medical non-compliance, etc.)

For BPH cohort:

  • Subject requires simultaneous upper urinary calculi lithotripsy procedure (not applicable to bladder calculi)
  • Unwilling or unable to provide consent
  • Any other condition which, in the opinion of the investigator, precludes study participation (e.g., history of medical non-compliance, etc.)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 5 centers
  • Mayo Clinic Phoenix — Phoenix
  • University of Miami Hospital — Miami
  • University of South Florida — Tampa
  • Indiana University Medical Center — Indianapolis
  • Duke University Medical Center — Durham

Identifiers

NCT: NCT06982235 · U0777

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗