Enrolling by invitation NCT02759744
Fusion Guided Focal Laser Ablation of Prostate Cancer
Prostate Cancer · Prostate Neoplasms
Urology
2,917 trials in this section
Not yet recruiting NCT07574541
Multitargeted Recombinant Ad5 PSA/MUC-1/Brachyury-Based Immunotherapy (TriAdeno) Vaccine With IL-15 Superagonist N-803 in Participants With Clinically Localized Prostate Cancer Undergoing Active Surveillance
Adenocarcinoma · Prostate Cancer · Neoplasms
Recruiting NCT03805919
Men at High Genetic Risk for Prostate Cancer
Prostatic Neoplasms
Recruiting NCT07493512
Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Not yet recruiting NCT07752134
Efficacy and Safety of Pregabalin Combined With Educational and Behavioral Intervention for Bladder Pain Syndrome/Interstitial Cystitis
Bladder Pain Syndrome · Pregabalin · Educational Behavioral Intervention
Recruiting NCT07184957
Prospective Database of Clinical Outcomes Following Cryotherapy for Ablation of Clinically Localized Prostate Cancer
Prostate Cancer
Recruiting NCT07751159
Radiation Therapy Approaches for People With Prostate Cancer
Prostate Cancer Patients · Non-metastatic Prostate Cancer · High Risk Prostate Cancer
Not yet recruiting NCT07753356
VALIDATION OF FUSION CEMEP SCORE FOR OMITTING SYSTEMATIC PROSTATE BIOPSY
Prostate Cancer · Prostatic Neoplasms/Diagnosis
Recruiting NCT07187778
Phase II Trial of Single Agent Belzutifan or Pembrolizumab Versus Combination as Neoadjuvant Therapy in Clear Cell Renal Cell Carcinoma (BLAZE)
Clear Cell Renal Cell Carcinoma
Recruiting NCT06161532
Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...
Small Cell Carcinoma of the Bladder · Small Cell Carcinoma of the Urinary Tract · Squamous Cell Carcinoma of the Bladder
Not yet recruiting NCT07753096
Predicting the Success of Flexible Ureterorenoscopy for Kidney and Upper Ureter Stones
Urolithiasis · Renal Stones · Upper Ureteric Stones
Not yet recruiting NCT07550517
PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT
High-Risk Localized Prostate Cancer
Recruiting NCT04706663
Precision-Based Genomics in Prostate Cancer
Prostate Cancer
Recruiting NCT07419295
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
Bladder Cancer
Not yet recruiting NCT07746414
Effects of Exercise Prior to Radical Prostatectomy
Recovery · Post Prostatectomy
Not yet recruiting NCT07667400
Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer
Head and Neck Cancer · Head and Neck Squamous Cell Carcinoma · Paranasal Sinus Neoplasms
Not yet recruiting NCT07751133
Evaluating Hormone Therapy to Achieve Optimal Doses in Metastatic Prostate Cancer
Prostate Cancer · mHSPC · mCRPC
Recruiting NCT07753343
Identification and Description of Patients With High-risk Non Metastatic RCC
Renal Cell Carcinoma
Not yet recruiting NCT07686380
IL-15 Superagonist With or Without Vaccine in Biochemically Recurrent Prostate Cancer After Previous Stereotactic Body Radiation Therapy
Recurrent Prostate Cancer · Prostate Cancer
Recruiting NCT07549256
Cannabidiol for Pain Relief of Patients With End-stage mCRPC
Metastatic Castration Resistant Prostate Cancer (mCRPC)
Not yet recruiting NCT07685249
Rehabilitation and Sex Therapy to Optimize Recovery After Prostate Cancer Treatment
Prostate Cancer · Urinary Incontinence · Erectile Dysfunction
Not yet recruiting NCT07751796
OptiCross HD IVUS for Assessing Invasion Depth in Upper Tract Urothelial Carcinoma
Upper Tract Urothelial Carcinoma
Recruiting NCT04752722
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve
Superficial Bladder Cancer · Non-muscle Invasive Bladder Cancer With Carcinoma in Situ · Non-muscle Invasive Bladder Cancer
Recruiting NCT07508124
Topical Steroids to Prevent Recurrent Urinary Tract Infections in Uncircumcised Male Infants: a Pilot Study
Urinary Tract Infection
Recruiting NCT04633252
A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate Cancer
Cancer Of Prostate · Prostate Neoplasms
Recruiting NCT00071526
Urinary Vitamin C Loss in Diabetic Subjects
Diabetes
Not yet recruiting NCT07748988
Pilot Study of Casdatifan-Treated Refractory Renal Cell Carcinoma
Refractory Renal Cell Carcinoma
Not yet recruiting NCT07749924
Active Surveillance Versus Adjuvant Intravesical Chemotherapy in Liquid Biopsy-Defined Low-Shedding Intermediate-Risk NMIBC
Bladder Cancer · Non-Muscle-Invasive Bladder Cancer (NMIBC)
Not yet recruiting NCT07742176
Transcutaneous Tibial Nerve Stimulation for Urinary Incontinence After Radical Prostatectomy
Urinary Incontinence (UI) · Prostatectomy
Recruiting NCT04221542
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
Prostate Cancer
Not yet recruiting NCT05725421
Transplantation of Reconstructed Renal Allografts Following Ex-Vivo Partial Nephrectomy
Renal Cell Carcinoma
Recruiting NCT06864533
Adjuvant Chemotherapy for High Malignant Prostate Cancer
Prostate Cancer · Radiation Therapy · Chemotherapy
Recruiting NCT07223385
High Cardiovascular Risk Intervention With Cardio-Oncology Consultation for Prostate Cancer Following Androgen Receptor Pathway Inhibitor (ARPI) Therapy (Heart-Safe)
Prostate Cancer (Diagnosis) · Prostate Cancer Stage IV · CV Risk
Recruiting NCT01050504
Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer
Localized Renal Pelvis and Ureter Urothelial Carcinoma · Malignant Solid Neoplasm · Metastatic Malignant Neoplasm in the Bone
Recruiting NCT07455903
Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT
Prostate Cancer · Localized Prostate Carcinoma
Recruiting NCT06417190
Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology
Muscle-Invasive Bladder Carcinoma · Tumor
Recruiting NCT07144228
Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer
Prostate Cancer (Diagnosis)
Recruiting NCT06439836
Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy
Metastatic Urothelial Carcinoma · Unresectable Urothelial Carcinoma
Recruiting NCT05987241
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
Muscle Invasive Bladder Urothelial Carcinoma · Muscle Invasive Renal Pelvis Urothelial Carcinoma · Muscle Invasive Ureter Urothelial Carcinoma
Not yet recruiting NCT07749794
Hydrodissection-Assisted Bipolar Prostatic Enucleation Versus Conventional Bipolar Enucleation
Prostatic Hyperplasia · Lower Urinary Tract Symptoms
Recruiting NCT07188896
A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)
Advanced Renal Cell Carcinoma (aRCC) · Metastatic Renal Cell Carcinoma ( mRCC) · Clear Cell Renal Cell Carcinoma (ccRCC)
Recruiting NCT06290687
Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy
Malignant Neoplasm of Bladder · Muscle Invasive Bladder Carcinoma
Recruiting NCT07483970
A Phase I/II Study of JL19001 Injection Alone or in Combination With BCG in Subjects With High Risk Non-Muscle Invasive Bladder Cancer.
High Risk Non-muscle Invasive Bladder Cancer
Recruiting NCT07566156
Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
Urothelial Cancer · Urinary Bladder Neoplasms
Recruiting NCT06995677
Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
Low-grade NMIBC · FGFR Gene Amplification · FGFR Gene Alterations
Recruiting NCT06907446
Comparison of New SUREcore Biopsy of Needle to Standard of Care During Transperineal Prostate Biopsies
Prostate Cancer
Recruiting NCT07529717
First-in-Human Study to Evaluate AZD8359 STEAP2 TCE in Participants With Prostate Cancer
Metastatic Prostate Cancer
Recruiting NCT06510374
Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer
Intermediate Risk Non-Muscle Invasive Bladder Cancer
Recruiting NCT07475806
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder
Muscle-invasive Bladder Cancer
Recruiting NCT04923178
A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies
Urothelial Cancer · Bladder Cancer · Genitourinary Cancer
Recruiting NCT07750470
Diagnostic Accuracy of 18F-FDG PET/CT in Muscle-invasive Bladder Cancer
Muscle-invasive Bladder Cancer
Recruiting NCT06145633
Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer
Castration-Resistant Prostate Carcinoma · Metastatic Prostate Adenocarcinoma · Stage IVB Prostate Cancer AJCC v8
Recruiting NCT07202884
A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight
Urinary Incontinence,Stress
Recruiting NCT07579195
Consolidative Therapy After EV + Pembrolizumab in Muscle Invasive Bladder Cancer, REINFORCE Trial
Muscle Invasive Bladder Carcinoma · Stage III Bladder Cancer AJCC v8 · Stage IV Bladder Cancer AJCC v8
Recruiting NCT05610852
Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound
Prostate Adenocarcinoma · Prostate Cancer
Recruiting NCT06545955
A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer
Non-muscle Invasive Bladder Cancer With Carcinoma in Situ
Recruiting NCT06940271
Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy
Localized Prostate Carcinoma · Stage I Prostate Cancer AJCC v8 · Stage II Prostate Cancer AJCC v8
Recruiting NCT05796375
Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance
Non-muscle-invasive Bladder Cancer
Recruiting NCT06931340
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
Castration-Sensitive Prostate Carcinoma · Metastatic Prostate Adenocarcinoma · Stage IVB Prostate Cancer AJCC v8
Recruiting NCT06632977
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
Castration-Resistant Prostate Carcinoma · Stage IVB Prostate Cancer AJCC v8
Recruiting NCT07747272
Nerve-SPARing Robotic Prostatectomy: The Impact of Patient Baseline Profiles on Erectile Function
Prostate Cancer · Prostatectomy · Robotic Surgery
Recruiting NCT06809140
Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer
Muscle Invasive Bladder Urothelial Carcinoma
Recruiting NCT07747727
Perineal Ultrasound, Post-Void Residual, and Lower-Limb Alignment in Stress Incontinence
Stress Urinary Incontinence in Women
Recruiting NCT07193511
BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)
Solid Tumor Cancer · Locally Advanced · Metastatic Solid Tumors
Recruiting NCT03866382
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Bladder Adenocarcinoma · Bladder Clear Cell Adenocarcinoma · Bladder Mixed Adenocarcinoma
Recruiting NCT07287150
A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer
Metastatic Castration-Resistant Prostate Cancer
Not yet recruiting NCT07747493
68Ga-PSMA-11 PET/MRI for Selecting Men With Prostate Cancer for Focal Therapy
Prostate Cancer (Adenocarcinoma) · Localized Prostate Cancer
Recruiting NCT07532941
Clinical Efficacy of Stopping Oral Antibiotics When Symptoms Stop, Compared to 'Finishing the Course'
Urinary Tract Infection · Cellulitis · Respiratory Tract Infections
Recruiting NCT06439862
Study of the Quality of Life in School Aged-children With Posterior Urethral Valves
Quality of Life · Posterior Urethral Valve · Renal Insufficiency
Recruiting NCT06661720
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Clear Cell Renal Cell Carcinoma · Renal Cell Carcinoma (RCC) · Stage II Renal Pelvis Cancer AJCC v8
Not yet recruiting NCT07746713
A Study of JNJ-98768111 in Participants With Advanced Prostate Cancer
Prostatic Neoplasms
Recruiting NCT07594106
REGN15505 (PSMAx4-1BB) Alone or in Combination With Cemiplimab or REGN4336 (PSMAxCD3) in Adult Patients With Metastatic Castration-Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma
Metastatic Castration-Resistant Prostate Cancer (mCRPC) · Clear Cell Renal Cell Carcinoma (ccRCC)
Recruiting NCT07200830
Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial
Metastatic Castration-Resistant Prostate Carcinoma · Metastatic Prostate Adenocarcinoma · Stage IVB Prostate Cancer AJCC v8
Recruiting NCT07747740
Sequential Gemcitabine Plus Docetaxel Versus Gemcitabine Plus Mitomycin C for BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer
Non-Muscle-Invasive Bladder Cancer · BCG-Unresponsive Bladder Cancer
Recruiting NCT07000084
Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy
Recurrent Non-Muscle Invasive Bladder Carcinoma · Stage 0a Bladder Cancer AJCC v8 · Stage I Bladder Cancer AJCC v8
Recruiting NCT07226544
Ivonescimab Prior to Surgery for the Treatment of High-Risk Localized Clear Cell Renal Cell Cancer
Localized Clear Cell Renal Cell Carcinoma · Resectable Clear Cell Renal Cell Carcinoma · Stage II Renal Cell Cancer AJCC v8
Not yet recruiting NCT07578324
TENS During Transperineal Prostate Biopsy
Prostate Cancer (Diagnosis) · Prostate Biopsy · Pain, Procedural
Recruiting NCT04235764
En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope Device
Bladder Cancer
Recruiting NCT01834001
Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy
Prostatic Neoplasms · Prostate Cancer
Recruiting NCT00050752
Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer
Renal Tumor Histology · Cutaneous Leiomyoma · Kidney Cancer
Recruiting NCT06770582
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial
Non-Muscle Invasive Bladder Urothelial Carcinoma · Recurrent Non-Muscle Invasive Bladder Urothelial Carcinoma · Stage I Bladder Cancer AJCC v8
Not yet recruiting NCT07744620
Treatment Efficacy for Overactive Bladder: Comparing Education, Biofeedback, and Nerve Stimulation
Urinary Bladder, Overactive · Urinary Incontinence, Urge
Recruiting NCT06076538
PET/MR for Characterization of Renal Masses (RMs)
Renal Tumor · Renal Cell Carcinoma · Renal Tumor, Benign
Recruiting NCT07740629
Does Use of a Pre-Procedure Educational Video for Urodynamic Testing Reduces Anxiety?
Urinary Incontinence · Urinary Bladder Overactive · Urinary Incontinence , Stress
Not yet recruiting NCT07650448
WATER IV PCa (AS Sub-study)
Localized Prostate Cancer
Recruiting NCT06960577
Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)
Urinary Bladder Neoplasms · Immune Checkpoint Inhibitors · Methotrexate
Recruiting NCT06245603
A Study to Evaluate Efficacy and Safety of Hydeal Cyst® Intravesical Instillations in Patients Treated With Intravesical Chemotherapy or Immunotherapy in Non-muscle Invasive Bladder Cancer
Non-muscle Invasive Bladder Cancer
Recruiting NCT07719361
A Study in Patients With Metastatic Castration-Resistant Prostate Cancer
Metastatic Castration Resistant Prostate Cancer · mCRPC · mCRPC (Metastatic Castration-resistant Prostate Cancer)
Not yet recruiting NCT07744958
RESTORE-BLADDER (REgistry on STrategies for Organ pREservation in Muscle-invasive BLADDER Cancer)
Muscle Invasive Bladder Cancer (MIBC)
Recruiting NCT07744932
SABR Combined With Axitinib and Toripalimab for Oligometastatic Renal Cell Carcinoma
Oligometastatic Clear Cell Renal Cell Carcinoma
Recruiting NCT07745361
Study of Oral MRT-2359 With Apalutamide in Prostate Cancer
Castration-Resistant Prostate Cancer (CRPC) · Castration-Resistant Prostate Cancer · Prostate Cancer
Recruiting NCT07644598
MRI-based Focal Intraprostatic Simultaneous Integrated Boost (SIB) Intensification With De-escalated Adaptive-risk SBRT for Patients With Low to Intermediate Risk Prostate Cancer
Prostate Cancer · Localized Prostate Carcinoma
Recruiting NCT06801236
Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer
Prostate Cancer (Adenocarcinoma) · mCRPC (Metastatic Castration-resistant Prostate Cancer)
Recruiting NCT07364071
Strategic Endocrine Therapy and Targeted Radiotherapy for Prostate Cancer
Prostate Adenocarcinoma
Recruiting NCT06524544
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
Locally Advanced Urothelial Carcinoma · Metastatic Urothelial Carcinoma · Unresectable Urothelial Carcinoma
Recruiting NCT04628767
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
Renal Pelvis and Ureter Urothelial Carcinoma
Not yet recruiting NCT07742436
Urinary and Sexual Symptoms in Patients With Hirschsprung Disease
Hirschsprung Disease
Recruiting NCT06124976
Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma
Urothelial Carcinoma of the Renal Pelvis and Ureter · Transitional Cell Cancer of the Renal Pelvis and Ureter
Recruiting NCT07611825
Gut Microbiota Modulation for Immunotherapy Resensitization in Advanced Renal Cell Carcinoma
Advanced RCC
Recruiting NCT05939414
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
Oligometastatic Prostate Cancer (OMPC)