Menu
Recruiting NCT05864976

Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning

— Observational Glioblastoma Multiforme

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Support Vector Machine.
Who it may be relevant to
Registry conditions: Glioblastoma Multiforme. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Advancing Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning - a Prospective Study

Overview

This study is investigating the use of a computer algorithm to analyze scans of the brain before surgery to predict how a person's tumor will respond to treatment.

Interventions

  • Device Support Vector Machine
    Machine learning algorithm

Primary outcome measures

  • Number of participants who are deemed as short-term survivor or a long-term survivor [Time frame: Through completion of follow-up (estimated to be 2 years)]

Eligibility criteria

Inclusion criteria

  • Must have a radiological diagnosis of a lesion in the brain with characteristics consistent with glioblastoma multiforme.
  • Must be planning to undergo a pre-operative MRI.
  • Must be at least 18 years old.
  • Must be able to understand and willing to sign an IRB approved written informed consent document.

Exclusion criteria

  • Contraindication to MRI.
  • Inability to have clinical follow-up (e.g., patient is out of town and will do follow-up elsewhere).

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • Washington University School of Medicine — St Louis

Identifiers

NCT: NCT05864976 · 202305045 · 2R01CA203861

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗