Not yet recruiting NCT07628257
Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of DTI and Rs-fMRI to a Preoperative FDG PET Strategy, With Neuropsychological Correlates and Post-treatment Follow-up
Glioblastoma
CNS tumors
876 trials in this section
Recruiting NCT04547777
Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma
Glioma, Malignant
Not yet recruiting NCT07274787
Safety And Effectiveness Of NaviFUS System With Bevacizumab In Recurrent Glioblastoma
GBM
Recruiting NCT07223034
A Study of 177Lu-PSMA-617 in People With Gliomas
Glioma · Diffuse Astrocytoma, IDH-Wildtype (Grade 2-4) · Glioblastoma, IDH-wildtype
Recruiting NCT06607692
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).
Solid Tumor Cancer · Medulloblastoma · High Risk Neuroblastoma
Recruiting NCT07465796
A First-in-Human Study of the CIPHER System During Brain Surgery for Newly Diagnosed Glioma
Glioma · Tumor · Electrocorticography
Not yet recruiting NCT07422896
A Phase I First-in-human Trial of Bvax (B-cell Vaccination) in Addition to Standard of Care Chemoradiotherapy for Newly Diagnosed Glioblastoma
Glioblastoma
Recruiting NCT06533163
Low-Intensity Oscillatory Magnetic Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme (GBM) - An Exposure-time Escalation Pilot Trial
Glioblastoma Multiforme
Not yet recruiting NCT05676489
MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors
Healthy Volunteers · Recurrent Glioma · Brain Metastases From Extra-cranial Solid Tumors
Not yet recruiting NCT07620548
Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas
Glioblastoma · Glioblastoma, IDH-wildtype · Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Recruiting NCT07620470
Spectral Precise Image Study for Brain Tumors
Brain Tumors
Recruiting NCT05632562
Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma
High Grade Glioma
Recruiting NCT07617168
The Effect of Education Brain Tumors
Primary Brain Neoplasms
Not yet recruiting NCT07621146
A Comparison of [68Ga]DOTATATE and [18F]AmBF3TATE for the Staging and Assessment of Neuroendocrine Malignancies
Neuroendocrine Tumors, NET · Pheochromocytoma/Paraganglioma · SSTR-expressing Tumors
Recruiting NCT05271240
Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM
Glioblastoma · Glioblastoma Multiforme · Glioma, Malignant
Recruiting NCT05979064
Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)
Glioma · Glioma, Malignant · Glioblastoma
Recruiting NCT05954858
Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma
Glioma, Malignant · Glioblastoma · Glioblastoma Multiforme
Not yet recruiting NCT07616726
Exploration and Characterization Ofintratumoral Electrophysiological Heterogeneity in Gliomas Using Magnetoencephalography
Patients Diagnosed With a Malignant Glioma
Recruiting NCT07616986
LITT for Ultra-early GBM Recurrence
Glioblastoma (GBM) · Glioblastoma - Category
Not yet recruiting NCT07346157
Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease
Medulloblastoma · Medulloblastoma, Childhood · Medulloblastoma Recurrent
Recruiting NCT06397560
PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial
Glioma · Glioma, Malignant · Recurrent Glioma
Recruiting NCT03213002
Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM
Glioblastoma Multiforme (GBM) · Glioblastoma · Glioma of Brain
Recruiting NCT02861898
Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
Glioblastoma · Brain Cancer · Brain Neoplasm
Recruiting NCT07612917
Brain Connectivity Changes in Glioma Patients During Treatment
Glioma (Any Grade) in the Brain · Gliomas, Malignant · fMRI Research
Not yet recruiting NCT07613450
A Phase III Study of SYHA1813 for Recurrent or Progressive High-Grade Meningiomas
High Grade Meningioma
Not yet recruiting NCT07609472
FG001 Near-Infrared Fluorescence Imaging During Tumor Resection in Newly Diagnosed High-Grade Glioma
High-Grade Glioma (WHO III-IV)
Recruiting NCT06831526
Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma
Glioblastoma
Recruiting NCT00107289
Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma
Neuroblastoma · Pheochromocytoma
Enrolling by invitation NCT05116137
The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors
Glioblastoma Multiforme of Brain · Brain Cancer
Recruiting NCT07239115
Levetiracetam for Seizure Prevention After Brain Tumor Surgery
Postoperative Seizures After Brain Tumor Surgery
Recruiting NCT07243470
Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors
Glioma · CNS Tumor, Adult · CNS Tumor, Childhood
Recruiting NCT06254326
ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients
Recurrent Oligodendroglioma · Progressive Oligodendroglioma
Recruiting NCT04752280
Glioblastoma Radiotherapy Using IMRT or Proton Beams
Glioblastoma
Recruiting NCT07424092
Intratumoral DNX-2401 for High Grade Pediatric Brain Tumors
High Grade Glioma · Ependymoma · Embryonal Tumor of Brain
Recruiting NCT07608003
Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis:
Gliomas Harboring IDH1 and/or IDH2 Mutations · Glioma Glioblastoma Multiforme · Glioma of Brainstem
Recruiting NCT07411690
Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors
Brain Tumor Adult · Brain Tumor Benign · CerebroSpinal Fluid (CSF) Leak
Recruiting NCT06807619
A Study of Sotorasib in People With Brain Tumors
Brain Tumor
Recruiting NCT07374692
Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors
Recurrent CNS Tumors · Brain Cancer · Gliomas
Not yet recruiting NCT07604285
A Phase 1/2 Study of Safety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated Glioblastoma
Glioblastoma
Recruiting NCT04635657
Cognitive Status After Removal of Skull Base Meningioma
Meningioma · Skull Base Meningioma · Frontal Meningioma
Recruiting NCT07150806
RYZ101 for the Treatment of Progressive or Recurrent Intracranial Meningioma
Recurrent Meningioma
Not yet recruiting NCT07226466
Evaluating Biomarkers of Cognitive Dysfunction in Patients With Cancer
Brain Tumor Adult · Brain Metastases From Solid Tumors · Brain Tumor, Primary
Recruiting NCT02754544
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
Brain Neoplasm · Metastatic Malignant Neoplasm in the Brain · Recurrent Brain Neoplasm
Recruiting NCT07413796
Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures
Brain Tumor Adult · Brain Tumor Benign · Meningioma
Recruiting NCT07599371
A Prospective, Single-arm Clinical Study on the Safety and Efficacy of Ivoximab Combined With Temozolomide in the Treatment of Relapsed/Refractory Glioma
Relapsed/Refractory Glioma
Recruiting NCT05342454
A Comprehensive Clinical fMRI Software Solution to Enable Mapping of Critical Functional Networks and Cerebrovascular Reactivity in the Brain
Brain Tumor
Not yet recruiting NCT07599917
Diagnostic Performance and Quantitative Analysis of [18F]FET PET in Brain Tumours
Brain Tumors
Not yet recruiting NCT07590726
PIRe 2.0: A Stepped-Care Model for Involving Relatives Across Sectors
Brain Injuries, Acute · Brain Tumor Adult · Brain (Nervous System) Cancers
Recruiting NCT01668082
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
Brain Mass
Recruiting NCT05500612
MRI Hypoxia Study for Glioblastoma Multiforme (GBM) Radiation Therapy
Glioblastoma Multiforme
Recruiting NCT07418775
Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With Meningioma
Meningioma of Brain · Meningioma · Brain Tumor
Enrolling by invitation NCT07595666
Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.
Dementia · Movement Disorders · ALS - Amyotrophic Lateral Sclerosis
Recruiting NCT05755399
Feasibility of Transcranial Focused Ultrasound to Measure Brain Tumor
Cranial Neurosurgery
Recruiting NCT05871021
Protective VEGF Inhibition for Isotoxic Dose Escalation in Glioblastoma
Glioblastoma
Recruiting NCT06557512
Adjuvant Hypofractionated Stereotactic Radiosurgery for Intermediate-risk Meningioma
Meningioma · Meningioma, Malignant · Recurrent Meningioma
Recruiting NCT07338539
BIO-SHORT: Hypofractionated RT for Poor-Prognosis GBM
Glioma
Recruiting NCT07409584
Mental Health and Suicidality in Glioblastoma Patients in Germany
Glioblastoma (GBM)
Recruiting NCT06894979
Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma
Childhood Astrocytoma · Childhood Diffuse Intrinsic Pontine Glioma · Childhood Diffuse Midline Glioma
Not yet recruiting NCT07589361
Safety and Efficacy of Vertebral Body-Sparing Craniospinal Irradiation With Proton Therapy in Pediatric Tumors
Pediatric Central Nervous System Tumors · Medulloblastoma · Germinoma
Recruiting NCT06838676
ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas
Diffuse Intrinsic Pontine Gliomas (DIPG) · Progressive DIPG · Refractory DIPG
Recruiting NCT06389591
RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)
Recurrent Glioblastoma
Recruiting NCT07589257
A Study of VRT106 in Combination With Radiotherapy in Adult Patients With Diffuse Midline Glioma / Diffuse Intrinsic Pontine Glioma
Diffuse Midline Glioma, H3 K27M-Mutant · Diffuse Intrinsic Pontine Glioma
Recruiting NCT05281731
Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma
Glioblastoma · Glioblastoma Multiforme
Recruiting NCT07485049
BGB-58067 in Newly Diagnosed Glioblastoma Patients With MTAP-Deleted Tumors
Glioblastoma (GBM)
Recruiting NCT05425004
Cabozantinib for Patients With Recurrent or Progressive Meningioma
Meningioma
Recruiting NCT07584499
Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M) · Nasopharyngeal Carcinoma · Lymphoepithelial Carcinoma
Recruiting NCT05864534
Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma
Newly Diagnosed Glioblastoma · Glioblastoma, Isocitric Dehydrogenase (IDH)-Wildtype · Gliosarcoma
Recruiting NCT07003139
A Study of the Boron Neutron Capture Therapy (BNCT) Using B10 L-BPA in Malignant Brain Tumors
Malignant Brain Tumors
Recruiting NCT07539441
A Study of Mirdametinib in People With Central Nervous System Tumors
Central Nervous System Tumors · Glioma
Recruiting NCT06275919
Regorafenib for Recurrent Meningioma (MIRAGE Trial)
Meningioma, Malignant
Recruiting NCT06528691
Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors
High Grade Glioma · CNS Tumor
Recruiting NCT05096481
PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma
High Grade Glioma · Diffuse Intrinsic Pontine Glioma · Recurrent Medulloblastoma
Recruiting NCT05023434
A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumors
Brain Tumor · Brain Cancer · Motor Cortex; Lesion
Recruiting NCT04313140
Virtual Biopsy Development to Identify Patient's Glioma Grade at the CHU of Poitiers Using Magnetic Resonance Imaging
Development of the Virtual Biopsy · Tumor Grade · Artificial Intelligence Algorithms
Recruiting NCT06136611
Preoperative Preradiotherapy TTFields
Glioblastoma
Recruiting NCT07284069
Senicapoc and Perampanel for Newly Diagnosed Glioblastoma
Glioblastoma
Recruiting NCT04374305
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)
Neurofibromatosis Type 2 · Vestibular Schwannoma · Non-vestibular Schwannoma
Not yet recruiting NCT07568782
Impact of Fluorescence-Guided Resection and Chemoradiotherapy on the Systemic Immune Response in Glioblastoma: A Kinetic Analysis of Immune Biomarkers.
Glioblastoma
Recruiting NCT04699773
LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)
Glioma · Glioblastoma · Brain Tumor
Recruiting NCT07343986
Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated Glioblastoma
Glioblastoma (GBM)
Recruiting NCT07569042
A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma
Malignant Neoplasm of Brain
Recruiting NCT05553899
Utility of PET-MRI in Surveillance of Paediatric Brain Tumours
Brain Tumor, Pediatric
Recruiting NCT05293197
Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients
Malignant Brain Tumor · Malignant Glioma · Embryonal Tumor
Not yet recruiting NCT06804655
Pharmacoscopy for Patients With Refractory Primary Brain Tumors
Brain (Nervous System) Cancers · Glioblastoma · Glioma
Recruiting NCT06636162
Window of Opportunity Study of DSP-0390 in Gliomas
Glioma, Malignant · IDH Mutation
Recruiting NCT07567196
PET-Guided Resection in High-Grade Gliomas
Glioma Glioblastoma Multiforme · Glioma, High Grade · Glioma Surgery
Recruiting NCT05629702
ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids
Glioblastoma · Brain Tumor · Cannabis
Not yet recruiting NCT07567469
A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressive High-Grade Glioma or Posterior Fossa-A Ependymoma
High-Grade Glioma (HGG) · Posterior Fossa-A Ependymoma
Recruiting NCT04684368
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT
Central Nervous System Nongerminomatous Germ Cell Tumor · Choriocarcinoma · Embryonal Carcinoma
Recruiting NCT06649851
G-CSF After Chemo-radiation in Patients With Glioblastoma
MGMT-Methylated Glioblastoma · Glioblastoma (GBM) · Newly Diagnosed Glioblastoma Multiforme
Recruiting NCT06101069
Development of MRF for Characterization of Brain Tumors After Radiotherapy
Brain Tumor · Brain Necrosis · Brain Metastases
Recruiting NCT04274283
Tessa Jowell BRAIN MATRIX - Platform Study
Glioma
Recruiting NCT06810336
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery
Brain Injury · Brain Tumors · Craniotomy Surgery
Not yet recruiting NCT07452458
Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma
Glioblastoma, IDH-Wildtype · MGMT-Unmethylated Glioblastoma
Recruiting NCT06176066
PH Sensitive MRI Based Resections of Glioblastoma
Glioblastoma
Recruiting NCT06410248
Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma
Recurrent Glioblastoma, IDH-Wildtype · Recurrent WHO Grade 2 Glioma · Recurrent WHO Grade 3 Glioma
Recruiting NCT05230758
Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour
Medulloblastoma, Childhood · Cognitive Impairment
Not yet recruiting NCT07562971
Focused Ultrasound Blood-Brain Barrier Opening in Pontine Diffuse Midline Glioma to Enhance Temozolomide Therapy: Pilot Feasibility Study (FIDES)
Diffuse Midline Glioma, H3 K27-Altered
Recruiting NCT07560865
First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma
Astrocytoma · Glioblastoma · Progressive Disease
Not yet recruiting NCT07558395
Effectiveness of a Visual Telerehabilitation Program on Visual Perception in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain Tumour
Hemianopsia · Virtual Reality · Visual Rehabilitation