Not yet recruiting NCT07699172
EEG-Guided Cognitive Function Preservation in Patients With Brain Tumors
Glioma · Brain Neoplasm · Brain Tumor Adult
CNS tumors
876 trials in this section
Recruiting NCT06888817
Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases
Radiation Necrosis · High Grade Glioma (III or IV) · Brain Metastasases
Recruiting NCT07698665
Ketamine Versus Dexmedetomidine as an Adjuvant in Scalp Block in Supratentorial Brain Tumor Excision Surgeries
Regional Anesthesia Morbidity · Supratentorial Brain Tumor · Acute Pain
Recruiting NCT07698899
A Study of 177Lu-DTPA-Omburtamab in Children and Adolescents With Brain Cancer or Cancer That Has Spread to the Central Nervous System (CNS)
Recurrent Medulloblastoma · Refractory Medulloblastoma · CNS Metastases
Recruiting NCT07678684
A Study of HF1K16 Combined With Bevacizumab in Patients With Recurrent or Progressive Glioma
Glioma · Adult
Recruiting NCT06712875
MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas
Low Grade Glioma · High Grade Glioma
Not yet recruiting NCT07694622
Targeting MYC in High-Risk Medulloblastoma
Medulloblastoma
Recruiting NCT06408402
Impact of Environmental Exposures on Tumor Risk in SDHx-mutation Carriers
SDH-Related Familial Paraganglioma · SDHx-Related Syndromes · SDH Gene Mutation
Not yet recruiting NCT07694089
Steroid Avoidance, Dexamethasone, and RAGE Inhibition for Perioperative Cerebral Edema Management in High-Grade Gliomas
High-grade Gliomas (HGG)
Recruiting NCT07195591
Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
Glioblastoma
Recruiting NCT07688356
Belvarafenib for CNS Efficacy in Patients With BRAF-Altered Solid Tumors
Primary Brain Tumor · Metastatic Brain Tumor
Recruiting NCT05700071
MRS of Glioma Genomics
Glioma
Not yet recruiting NCT04903795
BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma
Newly Diagnosed Glioblastoma · Recurrent Glioblastoma
Recruiting NCT07174661
Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors
Advanced Malignant Solid Neoplasm · Malignant Brain Neoplasm · Recurrent Advanced Malignant Solid Neoplasm
Not yet recruiting NCT06448286
PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma
Glioblastoma
Recruiting NCT06701812
Digoxin Medulloblastoma Study
Medulloblastoma · Medulloblastoma, Non-WNT/Non-SHH
Recruiting NCT07085325
CSIMEMPHIS: Long-term Follow-up of Medulloblastoma Survivors That Received Craniospinal Irradiation
Medulloblastoma
Not yet recruiting NCT07685301
Development and Validation of an AI Foundation Model for CNS Tumor Classification
Brain Tumors · Central Nervous System Neoplasms
Recruiting NCT06427798
Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy
Somatostatin Receptor Positive · Gastrointestinal Neuroendocrine Tumors · Pheochromocytoma
Recruiting NCT07680205
An Experimental Study of Belzutifan Impact on Catecholamine Metabolism
Pheochromocytoma and Paraganglioma (PPGL) · Pheochromocytoma Malignant · Pheochromocytoma, Metastatic
Recruiting NCT07025226
Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease
Glioma
Not yet recruiting NCT07039760
Asciminib With or Without Sildenafil for Brain Tumors
Brain Tumor
Not yet recruiting NCT07678138
Exploratory Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of Tumor Neoantigen-pulsed Autologous Dendritic Cell Injection (YS247, Beijing YSCell Biotech Co., Ltd. [Abbreviated as YS])in Patients With Recurrent or Progressive Glioblastoma
Glioblastoma
Recruiting NCT07210632
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Brain Cancer · HGG · Glioma
Recruiting NCT06805305
DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)
Glioblastoma (GBM)
Recruiting NCT06465199
Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas
Atypical Teratoid/Rhabdoid Tumor · Embryonal Tumor With Multilayered Rosettes · Ewing Sarcoma
Recruiting NCT05303519
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
Glioma · Astrocytoma, Grade IV · IDH1-mutant Glioma
Recruiting NCT04837547
PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy
Neuroblastoma · Diffuse Intrinsic Pontine Glioma
Recruiting NCT07675070
Safety and Effectiveness Evaluation of Temozolomide (Amitzo, NanoAlvand) in Patients With Grade III and IV Glioma Tumors
Brain Tumor · Grade III Glioma · Grade IV Glioma
Recruiting NCT05864976
Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning
Glioblastoma Multiforme
Recruiting NCT07493447
Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures
Meningioma · Glioblastoma · Acoustic Neuroma
Recruiting NCT04085887
Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures
Brain Tumor
Not yet recruiting NCT07670455
Brain Radiotherapy Imaging for High-grade Glioma Using Hypoxia Targeting Through Oxygen-Enhanced Response
High Grade Gliomas · Hypoxia Brain · Glioblastoma (GBM)
Recruiting NCT05489783
Glioma Developmental and HyperActive Ras Tumor (DHART) Board
Glioma
Recruiting NCT07284628
Vortioxetine for Newly Diagnosed Glioblastoma
Glioblastoma
Recruiting NCT05658731
Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients
Brain Tumor · Head and Neck Cancer
Recruiting NCT07492316
RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB)
Recurrent Medulloblastoma
Recruiting NCT03510208
Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
Malignant Brain Neoplasm · Malignant Glioma
Recruiting NCT05009992
Combination Therapy for the Treatment of Diffuse Midline Gliomas
Diffuse Intrinsic Pontine Glioma · Diffuse Midline Glioma, H3 K27M-Mutant · Recurrent Diffuse Intrinsic Pontine Glioma
Recruiting NCT05588141
A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
Brain Tumor · Cancer
Recruiting NCT06905587
Methylphenidate in Pediatric Brain Tumor Survivors With Cancer-related Fatigue
Brain Tumor, Pediatric · Cancer-related Fatigue · Methylphenidate
Recruiting NCT07668869
TTFields Plus FET-PET-Guided Stereotactic Radiosurgery Versus TTFields Alone for Recurrent Glioblastoma (Tarrget 2.0)
Glioblastoma · Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype · Glioblastoma Multiforme, Adult
Recruiting NCT03180268
Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery
Grade 2 Meningioma · Intracranial Meningioma
Recruiting NCT06126588
Combination of Everolimus and 177Lu-DOTATATE in the Treatment of Grades 2 and 3 Refractory Meningioma: a Phase IIb Clinical Trial
Meningioma
Recruiting NCT06428045
STARLITE for Unresectable High-Grade Gliomas
High Grade Glioma
Recruiting NCT06014905
Feasibility of Acquiring Hyperpolarized Imaging in Patients With Meningioma
Meningioma
Recruiting NCT04573140
A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)
Adult Glioblastoma · High Grade Glioma · WHO Grade III or IV Malignant Glioma
Recruiting NCT06883747
Clinical Trial of BMS-986504 in Recurrent GBM Patients
Glioblastoma WHO Grade IV
Recruiting NCT07670026
Intensified Adjuvant Therapy for High-Risk Newly Diagnosed Glioblastoma With Subtotal Resection or Short-Term Progression
Glioblastoma
Enrolling by invitation NCT03914768
Immune Modulatory DC Vaccine Against Brain Tumor
Diffuse Intrinsic Pontine Glioma or Glioblastoma
Recruiting NCT05590689
Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor
Glioblastoma
Recruiting NCT07387666
Imaging Acetadote Metabolism in Glioblastoma
Glioblastoma · GBM
Recruiting NCT06962215
The Impact of Paramedic Training in Simulation on the Experience of Patients Treated for Malignant Brain Tumors in Neurosurgery (IPSIMANON)
Brain Tumor Adult
Enrolling by invitation NCT05435859
Functional Organization of the Superior Temporal Gyrus for Speech Perception
Epilepsy · Brain Tumor · Speech
Recruiting NCT06444412
An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma
WHO Grade 3 Glioma · WHO Grade 4 Glioma
Recruiting NCT07392957
Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma
Glioblastoma
Recruiting NCT07660458
Parental Distress and Treatment Adherence in Pediatric Recurrent Medulloblastoma
Medulloblastoma · Recurrent Medulloblastoma
Not yet recruiting NCT07650994
Movie-Watching Functional MRI for Mapping Brain Function in Neurosurgical Patients
Glioma · Brain Tumor Adult
Recruiting NCT07657403
CONNEctome-guided Navigation for Eloquent-area Tumor Surgery Trial
Brain Neoplasms · Eloquent Area Brain Tumors
Recruiting NCT05607407
Methimazole in Patients With Progressive Glioblastoma
Glioblastoma · Glioma
Recruiting NCT07375992
Music Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM)
Glioblastoma (GBM)
Recruiting NCT07655869
[177Lu]Lu-DOTA-EB-RGD2 Therapy in Patients With Recurrent High-grade Glioma
Recurrent High-Grade Gliomas · Recurrent Glioblastoma IDH Wildtype
Recruiting NCT03739411
Hyperpolarized Imaging in Diagnosing Participants With Glioma
Glioma
Recruiting NCT06319027
Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial
Glioblastoma, IDH-Wildtype
Recruiting NCT06193759
Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)
Medulloblastoma, Childhood · Atypical Teratoid/Rhabdoid Tumor of CNS · Embryonal Tumor With Multilayered Rosettes
Recruiting NCT04065776
Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma
Glioma · Pilocytic Astrocytoma · Pilomyxoid Astrocytoma
Recruiting NCT07541781
Sitagliptin in Recurrent/Progressive Grade 4 Glioma
Glioma · Glioblastoma · Recurrent Glioma
Recruiting NCT05859334
Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment
Recurrent Glioma · Recurrent WHO Grade 2 Glioma · Recurrent WHO Grade 3 Glioma
Recruiting NCT05947045
Cognitive Training in the Virtual Reality Setting With Children Undergoing Radiotherapy for Brain Tumors
Brain Tumor
Recruiting NCT04485559
Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
Recurrent World Health Organization (WHO) Grade II Glioma · Low-grade Glioma · High Grade Glioma
Recruiting NCT07648823
Dosimetry, Safety, and Efficacy Study of [177Lu]Lu-XT771 in Patients With Recurrent Glioblastoma
Recurrent Glioblastoma (WHO-Grade IV Glioma) · Recurrent Glioblastoma · Glioblastoma (GBM)
Recruiting NCT03750227
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
Malignant Solid Neoplasm · Metastatic Malignant Neoplasm in the Brain
Recruiting NCT06914479
Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors
Recurrent Diffuse Hemispheric Glioma, H3 G34-Mutant · Recurrent Malignant Brain Neoplasm · Resectable Brain Neoplasm
Recruiting NCT06666712
Chronic CED of TPT for Recurrent Malignant Glioma
Brain Tumor, Recurrent · Malignant Glioma (WHO Grade III or IV) · IDH1/IDH2 Mutation
Recruiting NCT06326190
177Lu-DOTATATE for Recurrent Meningioma
Recurrent Meningioma
Not yet recruiting NCT07570485
Feasibility Assessment of Adapted Physical Activity in Patients Treated for a Brain Tumor
Brain Tumor Adult
Not yet recruiting NCT07644312
Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPG
High Grade Glioma · Diffuse Intrinsic Pontine Glioma · WHO Grade 3 Glioma
Recruiting NCT06161974
Study of Olutasidenib and Temozolomide in HGG
High Grade Glioma · Astrocytoma · Astrocytoma, Grade III
Recruiting NCT05804227
Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas
Gliomas
Recruiting NCT07346144
Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma
Glioblastoma (GBM) · High Grade Gliomas · Recurrent Glioblastoma
Not yet recruiting NCT07422363
Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma
Recurrent Glioblastoma, IDH-Wildtype · Recurrent Gliosarcoma · Recurrent WHO Grade 4 Glioma
Recruiting NCT06575452
Using the Epitranscriptome to Diagnose and Treat Gliomas
Glioma
Recruiting NCT06622434
New Adjuvant Vaccine in Glioblastoma, a Phase 1/2a Study
Newly Diagnosed Glioblastoma
Recruiting NCT06666348
Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK
Pediatric Low-grade Glioma
Recruiting NCT04732065
ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors
Diffuse Midline Glioma (DMG) · Glioblastoma · Recurrent Ependymoma
Recruiting NCT06934889
Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma
Glioblastoma · Gliosarcoma
Recruiting NCT05576103
Longitudinal Prospective Study of Neurocognition & Neuroimaging in Primary BT Patients
Primary Brain Tumor · Glioma · Meningioma
Recruiting NCT05521984
Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)
Pediatric Brain Tumor · Pediatric Solid Tumor
Recruiting NCT07282587
Study of ONC206 (JZP3507) in Advanced Pheochromocytoma and Paraganglioma
Advanced Pheochromocytoma and Paraganglioma · PCPG
Recruiting NCT05393492
Regulating Emotions and Behaviors After Brain Injury
Acquired Brain Injury · Stroke/ Cerebrovascular Accident (Ischemic or Hemorrhagic) · Brain Tumor (After Recovery)
Recruiting NCT07635329
Home-based Vision Rehabilitation Guided by Brain Imaging
Visual Field Defect · Stroke · Hemianopia Homonymous
Enrolling by invitation NCT07634575
Triggered Imaging in Glioblastoma Based on Clinical Outcome Evaluation Compared to Routine: a Feasibility Study
Glioblastoma
Recruiting NCT07274397
Assessment of Early Post-operative Nuclear Imaging in Neurosurgery: a Safety and Feasibility Study in Patients Operated for Glioblastoma
Glioblastoma · Brain Tumors · Brain Imaging
Recruiting NCT06011109
Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab
Glioma · Glioblastoma Multiforme
Recruiting NCT05904119
Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study
First Progression of Glioblastoma
Recruiting NCT07631338
Low-grade Gliomas in Argentina: Incidence, Survival, and Therapeutic Strategies
Low-grade Glioma
Not yet recruiting NCT07629089
VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations
Brain Cancer
Recruiting NCT06883214
Three miRNA Signatures in Glioma: From Molecular Mechanisms to Potential Clinical Application
Glioma
Recruiting NCT06087393
CONVIVO Endomicroscopy
Brain Tumor
Recruiting NCT07627334
Personalized Targeted Glioblastoma Therapies by ex Vivo Drug Screening: Advanced Brain Tumor TheRApy Clinical Trial In Patients Scheduled for shOrt Course radiatioN
Glioblastoma (GBM)