Minimum Effective Exercise Intensity in Sedentary Individuals
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Exercise.
- Кому может быть актуально
- Состояния в реестре: Sedentary Individuals Not Participating in Regular Exercise Training/Physical Activity. Базовые параметры: 30 лет — 55 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Финляндия
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Minimum Effective Exercise Intensity for Improving Cardiorespiratory Fitness and Cardiometabolic Health in Sedentary Individuals
Обзор
The aim of this randomized controlled intervention study is to examine the minimum exercise intensity that has an effect on cardiorespiratory fitness and/or cardiometabolic risk factors in sedentary adults. In addition, the study seeks to examine which background factors explain individual differences in exercise responses.
Подробное описание
The study consists of a 2-week baseline period followed by two 6-week intervention periods. The study will compare changes in the predefined outcome variables between the exercise intervention groups and the control group that does not perform any exercise training. In addition to intensity prescribed relative to oxygen uptake reserve, exercise intensity will be retrospectively analyzed in relation to the first ventilatory threshold in order to examine the lowest effective intensity using this method as well. Among background factors, possible modifiers assumed on the basis of previous literature, will be analyzed to assess their contribution to inter-individual differences in the outcome responses. Potential main contributors are considered to be sex, the basal value of the outcome, nutritional habits, physical activity and stationary behavior outside the prescribed training, and non-invasive indicators of stress.
Вмешательства
- Другое Exercise
6 weeks of 3 x 30 min/week supervised cycle ergometer training and 6 weeks of 3 x 40-50 min/week supervised cycle ergometer training
Первичные конечные точки
- Maximal oxygen consumption [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Ventilatory thresholds [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
Вторичные конечные точки (12)
- Pmax [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Concentration of LDL cholesterol [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Concentration of HDL cholesterol [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Concentration of total cholesterol [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Concentration of triglycerides [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Concentration of blood glucose [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Concentration of insulin [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- HOMA-IR [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- HbA1c [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Blood pressure [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Resting heart rate [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
- Resting heart rate variability [Срок оценки: Pre (week 0), mid (after 6 weeks), post (after 12 weeks)]
Критерии участия
Критерии включения
- 30-50-year old males and females
- Sedentary, not participating in regular exercise training/physical activity
Критерии исключения
- Cardiovascular symptoms/diseases
- Musculoskeletal symptoms/diseases
- Metabolic diseases
- Resting blood pressure > 160/100 mmHg
- Body mass index ≥ 35
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Да
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Параллельные группы
- Маскирование
- Простое слепое
- Основная цель
- Фундаментальное исследование
Центры проведения
Финляндия · 2 центра
- UKK institute for Health Promotion Research — Tampere
- Paavo Nurmi Centre — Turku
Идентификаторы
NCT: NCT07418619 · MINI26