Multicomponent Training and Muscle Quality in Older Women

Официальное название

Effect of a Multicomponent Exercise Program on Muscle Quality Assessed by Ultrasound, Body Composition, and Functionality in Older Women: A Randomized Controlled Trial Protocol

Обзор

This study aims to evlauate the effect os a 32-week multicomponent training (MT) program on muscle architecture and muscle quality (assessed by ultrasound) in womer over 60 years. The study will also analyze concurrent changes in muscle strength, physical performance, and body composition. The hypothesis is that the training will induce positive architectural adaptations, such as reduced echogenicity and increased thickness in the rectus femoris and rectus abdominis muscles, correlating with improved functional independence.

Подробное описание

Population aging emphasizes the need for "healthy aging", where muscle quality (MQ) is a vital metric. However, there is a lack of robust longitudinal protocols integrating ultrasound-assessed MQ with functional performance in older women. This randomized controlled trial involves community-dwelling women aged 60+ from the Geriatric Revitalization Program in Salamanca. Participants will be randomized (1:1) into an experimental group (multicomponent training) or a control group. The intervention is a 32-week supervised program (3 sessions/week, 50 min/session) combining aerobic, strength, balance, and coordination exercises. Primary outcomes focus on muscle architecture (echo intensity and thickness) in the rectus femoris and rectus abdominis muscles. Secondary outcomes include functional capacity (SPPB, TUG, 5-time sit-to-stand), handgrip strength, and body composition.

Вмешательства

• Другое Multicomponent training
  The exercise battery includes lower body work (squats, deadlifts, front and sagittal plane lunges, hip abduction/extension, and plantar flexion) and upper body work (wall flexion-extensions, shoulder raises, and elbow flexion-extensions). In addition to the strength exercises mentioned above, balance exercises such as walking in tandem, standing on one leg, side steps, and weight transfer will also be performed. Aerobic capacity will be worked on by walking at a moderate intensity, and flexibili

Первичные конечные точки

• Echo intensity [Срок оценки: Baseline and 32 weeks]
• Muscle thickness (mm) [Срок оценки: Baseline and 32 weeks]
• Cross-sectional area [Срок оценки: Baseline and 32 weeks]
• Subcutaneous adipose tissue thickness [Срок оценки: Baseline and 32 weeks]

Вторичные конечные точки (8)

• Handgrip strength (kg) [Срок оценки: Baseline and 32 weeks]
• Short Physical Performance Battery (SPPB) [Срок оценки: Baseline and 32 weeks]
• Timed Up and Go (TUG) [Срок оценки: Baseline and 32 weeks]
• 5-time sit-to-stand (5STS) [Срок оценки: Baseline and 32 weeks]
• Body Mass Index (BMI) [Срок оценки: Baseline and 32 weeks]
• Body Fat Percentage [Срок оценки: Baseline and 32 weeks]
• Abdominal Circumference [Срок оценки: Baseline and 32 weeks]
• Waist-to-Hip Ratio [Срок оценки: Baseline and 32 weeks.]

Критерии участия

Критерии включения

• Being a woman over 60 years of age, residing in the community, and enrolled in the GPR

Критерии исключения

• Having neuromuscular diseases, recent abdominal surgery, metal implants incompatible with measurements, unstable cardiovascular diseases, or previous participation in another exercise program.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

Испания · 1 центр

• University of Salamanca — Salamanca

Идентификаторы

NCT: NCT07359495 · USalamancaMTUS

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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