Recruiting NCT07751159
Radiation Therapy Approaches for People With Prostate Cancer
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Brachytherapy, SBRT.
- Who it may be relevant to
- Registry conditions: Prostate Cancer Patients, Non-metastatic Prostate Cancer, High Risk Prostate Cancer. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Balancing Radiation Intensification and Quality of Life in Higher-Risk Prostate Cancer (The BALANCE-RT Trial)
Overview
The purpose of the study is to explore the best ways of giving radiation therapy to balance cancer control and treatment side effects.
Interventions
- Radiation Brachytherapy
Standard of care Brachytherapy - Drug SBRT
SBRT alone
Primary outcome measures
- Change in International Prostate Symptom Score / IPSS at 3 months [Time frame: 3 months]
Eligibility criteria
Inclusion criteria
- Non-metastatic prostate cancer.
- Classified as unfavorable intermediate-, high-, or very high-risk prostate cancer according to NCCN risk stratification guidelines. (Note: cT3a or T3b by MRI or PSMA PET allowed)
- Considered by the treating radiation oncologist as a suitable candidate for both HDR brachytherapy boost and SBRT (see clinical considerations for treatment eligibility below)
Exclusion criteria
- None
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
United States · 7 centers
- Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities) — Basking Ridge
- Memorial Sloan Kettering at Monmouth (Limited Protocol Activities) — Middletown
- Memorial Sloan Kettering at Bergen (Limited Protocol Activities) — Montvale
- Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities) — Commack
- Memorial Sloan Kettering at Westchester (Limited Protocol Activities) — Harrison
- Memorial Sloan Kettering Cancer Center (All Protocol Activites) — New York
- Memorial Sloan Kettering at Nassau (Limited Protocol Activities) — Uniondale
Identifiers
NCT: NCT07751159 · 26-288