Stroke Volume Versus Inferior Vena Cava Collapsibility Index to Predict Postinduction Hypotension in Intestinal Obstruction
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Post-induction Hypotension, Intestinal Obstruction. Basic parameters: 40 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Postinduction hypotension (PIH) is a frequent complication during general anesthesia. This study aims to compare the predictive effectiveness and diagnostic accuracy of stroke volume (SV) measured via left ventricular outflow tract velocity time integral (LVOT-VTI) versus the inferior vena cava collapsibility index (IVC-CI) using transthoracic echocardiography. The assessment will be conducted in adult patients with intestinal obstruction undergoing exploratory abdominal surgery under general anesthesia.
Detailed description
Postinduction hypotension (PIH) is associated with adverse postoperative outcomes. In this diagnostic accuracy observational study, adult patients aged 40-70 years with intestinal obstruction undergoing exploratory abdominal surgery under general anesthesia will be enrolled at Ain Shams University Hospitals. Prior to induction of general anesthesia, transthoracic echocardiography (TTE) will be performed to measure the stroke volume (SV) via LVOT-VTI and the inferior vena cava collapsibility index (IVC-CI). Patients will receive standard rapid sequence induction, and hemodynamic parameters will be monitored post-induction to evaluate the predictive value, sensitivity, and specificity of SV versus IVC-CI for postinduction hypotension. Secondary outcomes including incidence of PIH, length of hospital stay, PACU recovery time, and postoperative nausea and vomiting will also be recorded.
Primary outcome measures
- Efficacy of SV versus IVC-CI as Predictors for Post-Induction Hypotension Efficacy of SV versus IVC-CI as Predictors for Post-Induction Hypotension [Time frame: Measured baseline pre-induction and compared immediately post-induction.]
Secondary outcome measures (3)
- Incidence of Post-Induction Hypotension Incidence of Post-Induction Hypotension [Time frame: Within 3 minutes following induction of general anesthesia.]
- Length of Hospital Stay Length of Hospital Stay [Time frame: From date of surgery until hospital discharge (up to 9 months).]
- Time to Recovery from Post-Anesthesia Care Unit (PACU) Time to Recovery from Post-Anesthesia Care Unit (PACU) [Time frame: Intraoperative / immediate postoperative period until PACU discharge (up to 24 hours).]
Eligibility criteria
Inclusion criteria
- Adult patients with intestinal bowel obstruction undergoing exploratory abdominal surgery under general anesthesia.
- Age 40 to 70 years old.
- Body Mass Index (BMI) = 18 to 25 kg/m2.
- American Society of Anesthesiologists (ASA) physical status grade I or II.
Exclusion criteria
- American Society of Anesthesiologists (ASA) physical status grade >= III.
- Patients in whom the IVC cannot be visualized or patients with poor echogenicity.
- Patients with hemodynamic instability.
- Patients with vascular, respiratory, or cardiac diseases (e.g., cardiomyopathy, heart valve disease, arrhythmia, or bad exercise tolerance).
- Pregnant patients.
- Difficult airway or multiple intubatio
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07742904 · FMASU MD49/2025