Nailfold Capillaroscopic Changes in Psoriasis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Nailfold Capillaroscopy.
- Who it may be relevant to
- Registry conditions: Psoriasis. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Nailfold Capillaroscopic Changes in Psoriasis and Its Correlation With Disease Severity
Overview
The goal of this observational study is to evaluate nailfold capillaroscopic changes in patients with psoriasis and to assess their correlation with disease severity. The study will also explore differences in capillaroscopic findings across different clinical types of psoriasis and skin phototypes (Fitzpatrick classification). The study will include patients diagnosed with psoriasis attending dermatology outpatient clinics. Participants will undergo clinical assessment and nailfold capillaroscopy to detect microvascular changes.
Interventions
- Other Nailfold Capillaroscopy
Participants will undergo nailfold capillaroscopy using a USB digital capillaroscope to assess microvascular changes in psoriatic patients. Clinical assessment including PASI score and evaluation of nail involvement will also be performed.
Primary outcome measures
- Nailfold capillaroscopic abnormalities in psoriasis patients [Time frame: Baseline]
Secondary outcome measures (1)
- Variation of nailfold capillaroscopic findings among different clinical types of psoriasis and correlation with disease severity (PASI score). [Time frame: Baseline]
Eligibility criteria
Inclusion criteria
- Patients clinically diagnosed with psoriasis.
Exclusion criteria
- Patients with connective tissue diseases (e.g., systemic sclerosis, SLE)
- Diabetes mellitus or peripheral vascular disease
- Current smokers
- Pregnant or lactating women
- Recent use of vasodilators or beta-blockers
- Manual workers exposed to vibrating tools
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Egypt · 1 center
- Al-Hussein University Hospital & Sayed Galal University Hospital — Cairo
Identifiers
NCT: NCT07693595 · PSO-NFC-PASI-2026