Recruiting NCT01425892
The Pathogenesis and Natural History of Sjogren's Disease
Sjogren's Syndrome · Salivary Gland · Pathogenesis
Autoimmune diseases
3,520 trials in this section
Not yet recruiting NCT07752264
A Phase I/II Study of Eque-cel in Subjects Withimmune-mediated Necrotizing Myopathy
Refractory Immune-mediated Necrotizing Myopathy
Not yet recruiting NCT07748000
A Study of LIQ861 (Inhaled Treprostinil) in Adults With Systemic Sclerosis Who Have Symptomatic Raynaud's Phenomenon Attacks
Raynaud's Phenomenon Secondary to Systemic Sclerosis
Recruiting NCT07606274
A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)
LMNA-Related Dilated Cardiomyopathy
Recruiting NCT06733935
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Systemic Sclerosis · Idiopathic Inflammatory Myopathies · Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Recruiting NCT07752446
Mediterranean Diet and Time-Restricted Feeding in Ulcerative Colitis Remission
Ulcerative Colitis (Disorder) · Inflammatory Bowel Disease (IBD)
Recruiting NCT00059748
Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases Including Juvenile Dermatomyositis
Autoinflammatory Disease · Juvenile Dermatomyositis
Recruiting NCT07262983
Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis
Hyper IgE Syndrome From STAT3 Mutation · Job s Syndrome · HIES
Recruiting NCT06687551
JAK Inhibitor Dose TAPering Strategy Study
Rheumatoid Arthritis (RA
Recruiting NCT06617325
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
Recruiting NCT05230173
Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission
Ulcerative Colitis · Crohn Disease
Recruiting NCT06664814
An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Primary Focal Segmental Glomerulosclerosis
Focal Segmental Glomerulosclerosis
Recruiting NCT07606352
Safety and Efficacy of STL303 In Patients With Primary Immunoglobulin A (IgA) Nephropathy
IgAN
Recruiting NCT06730126
Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients
Autoimmune Lymphoproliferative Syndrome
Recruiting NCT06266403
Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications
Amyotrophic Lateral Sclerosis
Not yet recruiting NCT07474649
A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events
Coronary Atherosclerosis · Mixed Dyslipidemia · Hypercholesterolemia
Not yet recruiting NCT07747155
A Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of PTT-621 in Patients With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC)
Recruiting NCT02579967
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Primary T-cell Immunodeficiency Disorders · Common Variable Immunodeficiency · Immune System Diseases
Recruiting NCT07052929
Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators
X-Linked Myotubular Myopathy
Recruiting NCT06570798
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Systemic Lupus Erythematosus · Active Refractory Rheumatoid Arthritis
Recruiting NCT07111065
FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)
Dermatomyositis (DM) · Juvenile Dermatomyositis (JDM)
Recruiting NCT07067463
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Multiple Sclerosis (MS) Primary Progressive
Recruiting NCT07498335
Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgAN
Berger Disease · Bergers Disease · IgA Nephropathy
Not yet recruiting NCT07734012
Mycophenolate After Stem Cell Transplant for Systemic Sclerosis
Systemic Sclerosis (SSc)
Recruiting NCT07168772
The Effect of a Probiotic Administration as an add-on Treatment in Multiple Sclerosis
Multiple Sclerosis
Not yet recruiting NCT06620692
A Study to Investigate the Efficacy and Safety Profile of GM-XANTHO [GM-XAN003] in Patients With Psoriasis
Psoriasis
Recruiting NCT06948110
Deciphering the Genetic Architecture of Autoimmune Diseases
Autoimmune Diseases
Recruiting NCT03225144
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Frontotemporal Dementia · Amyotrophic Lateral Sclerosis · Progressive Supranuclear Palsy
Not yet recruiting NCT07751315
A Study of QLS2404 Injection in Healthy Participants and Participants With Rheumatic Autoimmune Diseases
Systemic Lupus Erythematosus · Primary Sjögren's Syndrome
Recruiting NCT00001248
Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)
Multiple Sclerosis
Not yet recruiting NCT07752108
A Study of Zasocitinib in Adults With Non-pustular Palmoplantar Psoriasis
Palmoplantar Psoriasis
Recruiting NCT04844606
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Ulcerative Colitis · Ulcerative Colitis Chronic · Inflammatory Bowel Diseases
Recruiting NCT07286578
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
Cardiovascular Diseases · Myocardial Ischemia · Heart Diseases
Not yet recruiting NCT07726888
Efficacy and Safety of Guselkumab in Patients With Moderate-to-Severe Ulcerative Colitis
Ulcerative Colitis (Disorder) · Guselkumab
Not yet recruiting NCT07751848
A Study of Outcomes in Chinese Patients Treated With Anifrolumab Who Have Active Mod-severe Systemic Lupus Erythematosus
Lupus Erythematosus, Systemic
Recruiting NCT05509777
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
Crohn's Disease
Recruiting NCT07629583
To Evaluate the Effects of Cevostamab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis
Lupus Erythematosus, Systemic
Recruiting NCT06925542
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
SLE (Systemic Lupus) · Lupus Erythematosus, Systemic · Lupus Nephritis
Not yet recruiting NCT07619547
Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease
Inflammatory Bowel Disease · Crohn's Disease · Ulcerative Colitis
Not yet recruiting NCT07751081
Evaluation of the Effects of Colipral on Microbiota Gut Composition in Patients Presenting With Ulcerative Colitis During Remission Phase and Functional Disorders
Inflammatory Bowel Disease, Ulcerative Colitis Type · Functional Disorder of Gastrointestinal Tract
Enrolling by invitation NCT07411664
Objective Longitudinal Assessment of Postural Stability and Gait of Stroke, Parkinson's Disease and Multiple Sclerosis Using Instrumented Posturography and Three Dimensional Motion Analysis
Stroke · PARKINSON DISEASE (Disorder) · Multiple Sclerosis
Enrolling by invitation NCT04976322
A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
Recruiting NCT07613294
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
Atherosclerosis · Cardiovascular Diseases · Lipoprotein(a)
Recruiting NCT00001184
Immune Regulation in Ulcerative Colitis or Crohn s Disease
Inflammatory Bowel Disease · Ulcerative Colitis · Chrohn's Disease
Recruiting NCT06430801
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
Crohn's Disease
Recruiting NCT06636656
A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis
Ulcerative Colitis
Recruiting NCT07202598
Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis
Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Enteritis
Recruiting NCT07483099
A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease
Crohn Disease
Recruiting NCT07415044
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis (UC) · Ulcerative Colitis, Active Moderate · Ulcerative Colitis, Active Severe
Recruiting NCT06937086
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Ulcerative Colitis · Obesity or Overweight
Recruiting NCT07220083
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
Focal Segmental Glomerulosclerosis
Recruiting NCT07077746
HB-adMSCs for the Treatment of Crohn's Disease
Crohn Disease (CD)
Not yet recruiting NCT07275580
Antibiotic Prophylaxis After Simple Tooth Extraction in Immunosuppressed Patients With Autoimmune Rheumatic Diseases
Autoimmune Rheumatic Diseases · Tooth Extraction · Infection Prevention
Not yet recruiting NCT07748637
A Clinical Study to Evaluate the Safety and Efficacy of GT802 Injection in the Treatment of Relapsing/Refractory Multiple Sclerosis
Multiple Sclerosis (MS)
Recruiting NCT06056297
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
Neutropenia
Recruiting NCT06937099
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Crohn's Disease · Obesity or Overweight
Not yet recruiting NCT07503340
A Study to Evaluate Pharmacokinetics, Safety, Tolerability, Immunogenicity and Pharmacodynamic Effects of Subcutaneous Ocrelizumab Administration in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS)
Relapsing-remitting Multiple Sclerosis
Recruiting NCT07409181
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus
Recruiting NCT03600779
Application of ihMT MRI in Multiple Sclerosis
Sclerosis, Multiple
Recruiting NCT07186101
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Ulcerative Colitis
Recruiting NCT07483073
A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
Colitis, Ulcerative · Crohn Disease
Recruiting NCT07161999
Study of COYA 302 for the Treatment of ALS
Amyotrophic Lateral Sclerosis (ALS)
Not yet recruiting NCT07749664
DEL-1 and Thromboxane A2 in Diabetic Nephropathy Patients
Nephropathy, Diabetic
Not yet recruiting NCT07749157
A Study of Subcutaneously Administered RO7845860 in Participants With Relapsing Multiple Sclerosis
Relapsing Multiple Sclerosis
Not yet recruiting NCT07748728
TLL-018 in Patients With Moderate to Severe Active Rheumatoid Arthritis With Inadequate Response or Intolerance to csDMARDs
Rheumatoid Arthritis (RA)
Recruiting NCT07497087
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
Systemic Sclerosis
Recruiting NCT06147843
French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Enrolling by invitation NCT07750249
The MIMIGA Study is a Randomized, Double-blind, Placebo-controlled Crossover Trial Evaluating the Safety and Efficacy of SCFA vs. Placebo. Administered Orally Once Daily With Standard Care, it Aims to Prevent CKD Progression in Biopsy-proven IgA Nephropathy by Modulating the Gut Microbiome.
Primary IgA Nephropathy
Not yet recruiting NCT07749430
A Clinical Study of ACG102 Injection in Patients With Refractory Active Systemic Lupus Erythematosus
Refractory Active Systemic Lupus Erythematosus
Recruiting NCT07564596
A Phase 1b/2a Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erthematosus
Not yet recruiting NCT07749768
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative Colitis
Ulcerative Colitis (UC)
Recruiting NCT07220915
Supporting Weak Immune System During Autoimmune Therapy: Testing Panzyga to Prevent Infections
Hypogammaglobulinemia · Autoimmune Conditions · Rheumatic Conditions
Recruiting NCT06571669
BOOM-IBD2 Pivotal Clinical Trial
Ulcerative Colitis · Inflammatory Bowel Diseases
Recruiting NCT04804553
Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis
Active Juvenile Psoriatic Arthritis
Recruiting NCT07241390
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
Atherosclerosis Cardiovascular Disease · Chronic Kidney Disease
Not yet recruiting NCT07749651
A Study on the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of SHR-7012 in Healthy Adults
Cutaneous Lupus Erythematosus(CLE)
Recruiting NCT07299019
A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis
Secondary Progressive Multiple Sclerosis
Recruiting NCT07104565
Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders
Immune Thrombocytopenia
Not yet recruiting NCT07748156
SNC116 Therapy for Refractory Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
Not yet recruiting NCT07744191
A Clinical Trial of Antiplatelets in Psoriasis
Psoriasis (PsO) · Psoriatic Arthritis (PsA)
Recruiting NCT07325292
Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis
Multiple Sclerosis
Recruiting NCT05039619
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants
Lupus Nephritis
Recruiting NCT06259071
MuSK Myasthenia 1000 Study
Myasthenia Gravis · MuSK MG · MuSK Myasthenia Gravis
Not yet recruiting NCT07356232
Partial Enteral Nutrition as Therapeutic Augmentation of Advanced Pharmacological Therapy in Patients With Active Crohn's Disease
Crohn's Disease, Active
Not yet recruiting NCT07494396
An AI-Based Erythema Measurement System for Psoriasis Lesions
Psoriasis
Recruiting NCT06599697
The MIGHT Trial - An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing Myopathy
Anti-3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR) Immune-Mediated Necrotizing Myopathy
Recruiting NCT07748533
HY001N for Patients With Autoimmune Hemolytic Anemia After Failure ≥3 Lines of Therapy.
Autoimmune Hemolytic Anemia (AIHA)
Recruiting NCT06796504
The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study
Relapsing Remitting Multiple Sclerosis
Recruiting NCT07449702
An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis
Plaque Psoriasis
Recruiting NCT06325800
GlycOxiTOD: Multimodal Vascular and Target-Organ Damage Registry
Hypertension · Target Organ Damage · Heart Disease Risk Factors
Recruiting NCT05799378
Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease
Systemic Lupus Erythematosus
Recruiting NCT07746583
A Study of Guselkumab Given After Ustekinumab in Participants With Moderate to Severe Psoriasis in Routine Clinical Practice
Psoriasis
Recruiting NCT07614477
Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of EVER001 in Participants With Selected Proteinuric Glomerular Diseases
Minimal Change Disease (MCD) · IgA Nephropathy (IgAN) · Focal Segmental Glomerulosclerosis (FSGS)
Not yet recruiting NCT07747467
A Study to Investigate the Safety and Tolerability of Multiple Study Interventions in Participants With Moderate to Severe Ulcerative Colitis
Colitis, Ulcerative
Recruiting NCT05435547
Preoperative Corticosteroids in Autoimmune Thyroid Disease
Graves Disease · Hashimoto Disease
Recruiting NCT07587125
Safety and Efficacy of S103 Cells in Progressive/Refractory Multiple Sclerosis
Multiple Sclerosis (MS) Primary Progressive · Multiple Sclerosis · Multiple Sclerosis (MS) Secondary Progressive
Recruiting NCT07674667
FUNCtion ALS: Aiming to Restore UNC13A Function in People Living With ALS
Amyotrophic Lateral Sclerosis
Recruiting NCT07039110
Study to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe Plaque Psoriasis
Plaque Psoriasis
Not yet recruiting NCT07747480
A Sub Study to Investigate the Safety and Tolerability of Aletekitug in Participants With Moderate To Severe Ulcerative Colitis
Colitis, Ulcerative
Recruiting NCT07237516
Zymfentra (Infliximab-dyyb) REal World Cohort STudy
Ulcerative Colitis (UC) · Crohn's Disease (CD) · Indeterminate Colitis