QIPB vs SI-FICB for Postoperative Analgesia After Total Hip Arthroplasty
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Supra-Inguinal Fascia Iliaca Compartment Block, Quadro-Iliac Plane Block.
- Who it may be relevant to
- Registry conditions: Hip Osteoarthritis, Total Hip Arthroplasty (THA), Postoperative Pain, Acute Pain. Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Comparison of Quadro-Iliac Plane Block and Supra-Inguinal Fascia Iliaca Compartment Block for Postoperative Analgesia in Total Hip Arthroplasty: A Prospective, Double-Blind, Non-Inferiority Study
Overview
Total hip arthroplasty (THA) causes moderate-to-severe postoperative pain. The PROSPECT guideline recommends the supra-inguinal fascia iliaca compartment block (SI-FICB) for THA, whereas evidence for newer quadratus-lumborum-family blocks is limited. The quadro-iliac plane block (QIPB) is a recently described fascial plane block, and no study has compared QIPB with SI-FICB head-to-head in any surgical context. In this prospective, double-blind, patients undergoing elective THA who receive one of the two routinely used preoperative blocks (SI-FICB or QIPB, chosen by the attending anesthesiologist as part of routine care) are systematically observed and compared. The primary objective is to assess whether the postoperative analgesic efficacy of QIPB is non-inferior to SI-FICB, using the resting NRS pain score at 6 hours postoperatively as the primary endpoint (non-inferiority margin Δ = 1.3).
Interventions
- Procedure Supra-Inguinal Fascia Iliaca Compartment Block
SIFICB is an ultrasound-guided fascial plane block performed via a supra-inguinal approach to the iliac fascia compartment, targeting the femoral nerve, lateral femoral cutaneous nerve, and obturator nerve. Single-shot, US-guided, 40 mL 0.25% bupivacaine, before GA induction. - Procedure Quadro-Iliac Plane Block
QIPB is a facial plane block performed under ultrasound guidance with local anesthetic in the interfascial plane between the erector spinae and the quadratus lumborum muscle, at the distal attachment site of the quadratus lumborum muscle on the iliac crest. Single-shot, US-guided, 40 mL 0.25% bupivacaine, before GA induction.
Primary outcome measures
- Pain intensity at rest at 6 hours postoperatively [Time frame: 6 hours after surgery]
Secondary outcome measures (3)
- NRS pain at rest [Time frame: 0, 2, 4, 6, 12, 24, 48 hours postoperatively]
- NRS pain on movement (active hip flexion) [Time frame: 0, 2, 4, 6, 12, 24, 48 hours postoperatively]
- Cumulative opioid consumption [Time frame: 24 hours and 48 hours]
Eligibility criteria
Inclusion criteria
- Adults aged 18-75 years
- Scheduled for elective primary total hip arthroplasty
- ASA physical status I-III
- Able to understand and communicate in Turkish and complete assessment scales
- Completed preoperative anesthesia evaluation and approved for surgery
- Signed written informed consent
Exclusion criteria
- Known allergy/contraindication to any local anesthetic, including bupivacaine
- Coagulopathy or anticoagulant/antiplatelet therapy contraindicating block (per ASRA 2022)
- Active infection or skin breakdown at the block site
- Chronic opioid use (≥3 months daily) or history of opioid dependence
- Morbid obesity (BMI > 40 kg/m²)
- Cognitive impairment or communication difficulty precluding reliable NRS/QoR-15 assessment
- Pregnancy or breastfeeding
- Revision THA or emergency THA for fracture
- Intraoperative complications requiring major protocol deviation (e.g., >1000 mL blood loss, cardiac arrest)
- Technically failed block (no sensory change at any region on the T1 cold test)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Other
Study locations
Turkey (Türkiye) · 1 center
- Dokuz Eylül University — Izmir
Identifiers
NCT: NCT07683663 · 2026/11-01