Enrolling by invitation NCT07665086
The Role of Isometric in Individuals With Rheumatoid Arthritis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Exercise.
- Who it may be relevant to
- Registry conditions: Isometric Exercise, Pain, Oxygenation. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
The Role of Isometric Exercise on Pain Modulation and Muscle Oxygenation in Individuals With Rheumatoid Arthritis
Overview
The aim of this study is to investigate the acute effects of isometric exercise on pain modulation and muscle oxygenation in individuals with rheumatoid arthritis.
Interventions
- Other Exercise
To determine isometric exercise intensity, a maximum repetition will be calculated individually using a handheld dynamometer. One maximum repetition will be defined as the highest value among the trials where participants squeezed the handheld dynamometer as hard as possible for 5 seconds. The average of 3 repetitions will be taken to determine one maximum repetition, with a 1-2 minute rest period between each repetition. 30% of one maximum repetition will be determined. The exercise will begin
Primary outcome measures
- Pain Tolerance Assessment [Time frame: Day 1]
- Pressure Pain Threshold Assessment [Time frame: Day 1]
- Temporal Summation Measurement [Time frame: Day 1]
- Conditional Pain Modulation Assessment [Time frame: Day 1]
- Visual Analog Scale (VAS) - Pain [Time frame: Day 1]
Secondary outcome measures (6)
- Quantitative Sensory Tests [Time frame: Day 1]
- Muscle Oxygen Saturation Measurement [Time frame: Day 1]
- The Body Awareness Questionnaire [Time frame: Day 1]
- ABILHAND Rheumatoid Arthritis Hand Function Questionnaire [Time frame: Day 1]
- Pain Catastrophizing Scale [Time frame: Day 1]
- The International Physical Activity Questionnaire - Short Form [Time frame: Day 1]
Eligibility criteria
Inclusion criteria
- Eligibility Criteria:
- Diagnosis of rheumatoid arthritis
- Being between 18-65 years of age
- Volunteering to participate in the study
Exclusion criteria
- Having a neurological disease
- Having pulmonary or cardiovascular problems that may affect daily living activities
- Sensory system disorders
- Previous upper extremity surgery
- Having cognitive impairment
- Having an accompanying rheumatic disease
- Fracture, dislocation, or surgical intervention in the hand/wrist region within the last 6 months
- Communication limitations that prevent following the study protocol
- Having an exercise history in the last six months
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
Turkey (Türkiye) · 1 center
- Pamukkale University — Denizli
Identifiers
NCT: NCT07665086 · Isometric Exercise