HoLEP Sexual Survivorship
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Telephone Interview, Questionnaires over the span of 24 months.
- Who it may be relevant to
- Registry conditions: BPH, Lower Urinary Tract Symptoms. Basic parameters: 18 years — 100 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Patient Perspectives on the Trade-off Between Voiding Improvement and Sexual Dysfunction Following HoLEP
Overview
The objective of this study is to evaluate how sexual function, ejaculatory function, and overall sexual satisfaction change following Holmium Laser Enucleation of the Prostate (HoLEP). In doing so, the study team will examine the trade-off between relief of lower urinary tract symptoms and changes in sexual function.
Detailed description
The objective of this study is to evaluate how sexual function, ejaculatory function, and overall sexual satisfaction change following Holmium Laser Enucleation of the Prostate (HoLEP).
Retrograde ejaculation is a common and expected consequence of the procedure and meaningfully influences surgical decision-making. Through the study team's findings, the study team aims to characterize the longitudinal impact of HoLEP and if it induces patient regret.
In doing so, the study team will examine the trade-off between relief of lower urinary tract symptoms and changes in sexual function. This study seeks to generate patient-centered data to inform shared decision-making for men considering HoLEP.
Interventions
- Other Telephone Interview
A one-time 30-45-minute telephone interview and discussion regarding the participants' after HoLEP experience and sexual satisfaction following HoLEP. - Other Questionnaires over the span of 24 months
Participants will complete questionnaires at 1, 3, 6, 12, and 24 months post-operatively
Primary outcome measures
- Ejaculatory function [Time frame: 1 year]
- Ejaculatory bother [Time frame: 1 year]
Secondary outcome measures (3)
- Erectile function [Time frame: 2 years]
- Sexual function [Time frame: 2 years]
- Sexual function and sexual satisfaction [Time frame: 2 years]
Eligibility criteria
Inclusion criteria
- Males 18-100 years old
- Electing to undergo HoLEP for the treatment of bothersome lower urinary tract symptoms
- Currently have present antegrade ejaculation (the standard, male ejaculatory process where semen is propelled forward and out through the urethra during orgasm).
Exclusion criteria
- Patients with any of the following:
- Indwelling urinary catheter prior to surgery
- Neurological disease
- History of prior prostatic/urethral surgery that may impact ejaculation
- Patients who lack decisional capacity
- Patients unable to read, understand, and speak English
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Northwestern University — Chicago
Identifiers
NCT: NCT07660068 · STU00226001