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Not yet recruiting NCT07639632

Reduce Inefficiencies in Management of Spasticity

No phase Interventional Stroke

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Screener, Standard of care.
Who it may be relevant to
Registry conditions: Stroke. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The purpose of this study is to evaluate the effectiveness of a spasticity screener and to determine if the spasticity screener results are useful to healthcare providers and impact clinical decision making

Interventions

  • Other Screener
    Participants will be screened for spasticity using the 2 question version of the Post-stroke Spasticity Monitoring Questionnaire (PSMQ) at 2 days after discharge, 2 weeks post stroke, 1 month post stroke, 3 months post stroke and every 3 months after for a total of 12 screenings across 24 months
  • Other Standard of care
    Observational data for the standard of care group will be obtained via phone every 3 months post stroke up to 24 months, utilizing the Standard of Care Group Questionnaire.

Primary outcome measures

  • Time to detect spasticity from incidence of stroke [Time frame: From baseline to 24 months after stroke]
Secondary outcome measures (2)
  • Time to referral for spasticity from incidence of stroke [Time frame: From baseline to 24 months after stroke]
  • The time from incidence of stroke to Botulinum neurotoxin (BoNT) administration [Time frame: From baseline to 24 months after stroke]

Eligibility criteria

Inclusion criteria

  • Currently admitted for an acute hemorrhagic or ischemic stroke; recurrent stroke allowed if no spasticity at baseline
  • NIHSS score of > 0 on items 5 or 6 (required of at least 1 limb)
  • Willingness to participate in the study for 24 months
  • Able to sign consent form or availability of a legally authorized representative to sign
  • Able to read/write in English
  • Identified MD for follow up post hospitalization

Exclusion criteria

  • Botulinum toxin use for any indication within the past 12 weeks
  • Acute life threatening illness
  • Prior limb injury or neurological diagnosis that limited movement in the now affected limb(s)
  • Any terminal illness that would limit participation in study follow ups
  • Known spasticity or other movement disorders that impact tone

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Diagnostic

Study locations

United States · 1 center
  • The University of Texas Health Science Center at Houston PO Box 20036 — Houston

Identifiers

NCT: NCT07639632 · HSC-MS-26-0099

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗