The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Paravertebral block group, İntertransverse process block group, Erector spinae plane block group.
- Who it may be relevant to
- Registry conditions: Thoracic Surgery, Videoassisted Thoracoscopic Surgery,One-lung Ventilation, Regional Anaesthesia, Postoperative Analgesia. Basic parameters: 18 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Effect of Paravertebral Block, Intertransverse Block, and Erector Spinae Plane Block on Postoperative Opioid Consumption and Pain Scores in Video-assisted Thoracic Surgery: a Prospective Observational Study
Overview
This present study aims is to compare the effects of ultrasound-guided paravertebral block, intertransverse process block, and erector spinae plane block on postoperative opioid consumption, and pain scores in patients undergoing VATS.
Detailed description
Video-assisted thoracic surgery (VATS) has become increasingly popular in Thoracic Surgery due to faster recovery and less postoperative pain compared to thoracotomy. However, although VATS has been reported to cause less postoperative pain than thoracotomy, it has also been shown to significantly increase the risk of acute and chronic postoperative pain, which negatively impacts postoperative pain recovery. Inadequate postoperative pain management can reduce the quality of a patient's recovery and increase the risk of postoperative pulmonary complication. Therefore, controlling pain in patients undergoing VATS is key to ensuring early mobilisation, and minimising the risk of pulmonary complications. Regional anaesthesia techniques are an important part of multimodal analgesia approach in patients undergoing VATS. The aim of the present study is to compare the effects of ultrasound-guided regional anaesthesia techniques on postoperative opioid consumption, and pain scores in patients undergoing VATS.
Interventions
- Other Paravertebral block group
Before the surgery, ultrasoud-guided paravertebral block will be performed before the surgery under standart anaesthesia monitoring - Other İntertransverse process block group
Before the surgery, ultrasoud-guided intertransverse process block will be performed before the surgery under standart anaesthesia monitoring - Other Erector spinae plane block group
Before the surgery, ultrasoud-guided erector spinae plane block will be performed before the surgery under standart anaesthesia monitoring
Primary outcome measures
- Postoperative opioid consumption [Time frame: 24 hours]
Secondary outcome measures (2)
- Postoperative Numerical Rating Scale (NRS) pain scores [Time frame: postoperative 24 hours]
- Chronic pain [Time frame: 3 months]
Eligibility criteria
Inclusion criteria
- aged 18-75 years
- American Society of Anaesthesiology (ASA) score I-III
- body mass index (BMI) <35kg/m2
- scheduled for elective VATS
Exclusion criteria
- ASA score ≥4
- BMI ≥35 kg/m2
- declining to give written informed consent
- controendications for block application
- inability to undergo block application
- history neurological disease or peripheral nerve disease
- history of chronic opioid use
- history of severe liver or kidney failure
- patients admitted to the intensive care unit postoperatively intubated
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-control
Study locations
Turkey (Türkiye) · 1 center
- University of Health Sciences, Antalya Training and Research Hospital — Antalya
Publications
- Supphapipat K, Samerchua A, Leurcharusmee P, Lapisatepun P, Pipanmekaporn T, Konkarn N, Prapussarakul K, Jinadech T, Wanvoharn M. Single- versus Multiple-Injection Intertransverse Process Block for VATS: A Randomized Trial on Dermatomal Sensory Blockade. J Pain Res. 2025 Sep 15;18:4791-4800. doi: 10.2147/JPR.S545731. eCollection 2025. PMID 40978546
- Sandeep B, Huang X, Li Y, Xiong D, Zhu B, Xiao Z. A comparison of regional anesthesia techniques in patients undergoing video-assisted thoracic surgery: A network meta-analysis. Int J Surg. 2022 Sep;105:106840. doi: 10.1016/j.ijsu.2022.106840. Epub 2022 Aug 24. PMID 36030040
Identifiers
NCT: NCT07578545 · 7/24