Recruiting NCT06890598
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Carcinoma, Non-Small-Cell Lung
Lung cancer
3,760 trials in this section
Recruiting NCT06694454
Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer (NSCLC) · Carcinoma, Non-Small Cell Lung · Non-Small Cell Lung Carcinoma
Recruiting NCT07554339
A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)
Non-small Cell Lung Cancer
Not yet recruiting NCT07746388
Adaptive Chemotherapy for Pd-l1 High REsEctablE NSCLC: A Chemo-PHREE Trial
Nsclc · NSCLC Stage II · NSCLC, Stage III
Not yet recruiting NCT07753278
Fresh Gas Flow and Lung Ultrasonography in Laparoscopic Cholecystectomy
Postoperative Atelectasis · Pulmonary Atelectasis
Recruiting NCT06561685
A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors
Metastatic Solid Tumor · Advanced Solid Tumor · Non-small Cell Lung Cancer
Recruiting NCT07613099
Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging
Allogeneic Stem Cell Transplantation · Lung Allograft Transplantation · Interstitial Lung Disease
Recruiting NCT01950572
Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma
Thymoma · Stomach Neoplasms · Pancreatic Neoplasms
Recruiting NCT04431024
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome
Familial Cancer · BRCA1-Associated Protein-1 (BAP1) Mutations · Tumor Predisposition Syndrome (TPDS)
Not yet recruiting NCT07750717
Bedside Spirometry for Acute Lung Injury
Respiratory Insufficiency
Recruiting NCT07575763
CT-Guided vs Conventional DLT Sizing in Thoracic Surgery
Thoracic Surgery · One-lung Ventilation
Recruiting NCT06422143
Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]
Non-small Cell Lung Cancer · NSCLC
Not yet recruiting NCT07752875
A Study of LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C Mutation
Ovarian Cancer · Small Cell Lung Cancer · Non Small Cell Lung Cancer
Not yet recruiting NCT07752966
Evaluation of a Genetic Risk Score for Lung Metastasis and Prognosis in Breast Cancer
Breast Cancer Lung Metastasis
Recruiting NCT00034216
Collection of Blood From Patients With Cancer
Prostate Cancer · Breast Cancer · Colon Cancer
Recruiting NCT00471250
Collection of Lung Fluid and Tissue Samples for Research
Leukocyte Disorders · Respiratory Tract Diseases · Bronchoscopy
Recruiting NCT04267848
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Lung Non-Small Cell Carcinoma · Lung Non-Small Cell Squamous Carcinoma · Lung Non-Squamous Non-Small Cell Carcinoma
Recruiting NCT07531095
Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)
Small Cell Lung Cancer
Recruiting NCT04181060
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
Advanced Lung Non-Squamous Non-Small Cell Carcinoma · Metastatic Lung Non-Squamous Non-Small Cell Carcinoma · Recurrent Lung Non-Squamous Non-Small Cell Carcinoma
Recruiting NCT06399302
Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes
Lung Transplant; Complications · Lung Transplant; Infection or Inflammation · Lung Transplant Rejection
Enrolling by invitation NCT00068003
Harvesting Cells for Experimental Cancer Treatments
Melanoma · Gastrointestinal Cancer · Metastatic Cancer
Enrolling by invitation NCT07517692
Facilitation of Information eXchange for Shared Decision Making for Lung Cancer Screening
Lung Cancer Screening
Recruiting NCT07388524
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
Lung Non-Small Cell Carcinoma
Not yet recruiting NCT06948097
Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies
Lung Transplantation
Recruiting NCT07431827
MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013)
Non-small Cell Lung Cancer
Recruiting NCT06515990
A Study of DM005 in Patients With Advanced Solid Tumors
Carcinoma, Non-Small-Cell Lung · Squamous Cell Carcinoma of Head and Neck · Solid Carcinoma
Recruiting NCT07190248
A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)
Non-small Cell Lung Cancer
Recruiting NCT06424327
A Registry for People With Lung Cancer
Lung Cancer · Lung Cancer Stage I
Recruiting NCT04402788
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
Extensive Stage Lung Small Cell Carcinoma
Recruiting NCT02146170
Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors
Non-Small Cell Lung Cancer · Small Cell Lung Cancer · Extrapulmonary Small Cell Cancer
Recruiting NCT07566052
A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation
Non-small Cell Lung Cancer (NSCLC)
Not yet recruiting NCT07752589
Microbiota in Neoadjuvant Chemoimmunotherapy for NSCLC
Non-Small Cell Carcinoma of Lung · Gut Microbiomes · Neoadjuvant Chemoimmunotherapy
Recruiting NCT07751536
ctDNA-driven Adaptive Proton Craniospinal Irradiation in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis After Resistance to Third-Generation TKIs in the Consolidation Phase
Leptomeningeal Metastasis From Lung Cancer
Recruiting NCT00001823
Evaluation for NCI Surgery Branch Clinical Research Protocols
Synovial Cell Cancer · Melanoma · Colorectal Cancer
Recruiting NCT07738172
Osimertinib With or Without Primary Lung Tumor Resection for EGFR-Mutant Oligometastatic Non-Small Cell Lung Cancer
Lung Neoplasms, Non-Small Cell Lung Cancer
Recruiting NCT06793215
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer · KRAS G12C Lung Cancer
Recruiting NCT04410796
Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers
Metastatic Non-small Cell Lung Cancer
Recruiting NCT05995821
Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies
Head and Neck Cancer · Lung Cancer · Gastrointestinal Cancer
Recruiting NCT07472517
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy
Small Cell Lung Cancer (SCLC) · Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Recruiting NCT07155174
A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer
Small Cell Lung Cancer
Recruiting NCT06203210
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Small Cell Lung Cancer
Recruiting NCT05002478
Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial
Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) · Surfactant Dysfunction · Infant
Recruiting NCT06881784
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
NSCLC (Non-small Cell Lung Cancer) · Non-Small Cell Lung Cancer · NSCLC
Not yet recruiting NCT07673250
Personalized Ventilator Settings for Patients on ECMO
Acute Respiratory Distress Syndrome (ARDS) · Extracorporeal Membrane Oxygenation · Respiratory Failure Patients Treated With ECMO
Recruiting NCT07594067
TCR1188-ABC Cells in KRAS-mutated Cancers
Cholangiocarcinoma · Colorectal Cancer · Non-Small Cell Lung Cancer
Recruiting NCT06120283
BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
Advanced Solid Tumor · Advanced Breast Cancer · Metastatic Breast Cancer
Recruiting NCT05877599
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
Non-small Cell Lung Cancer · Head and Neck Squamous Cell Carcinoma · Colorectal Carcinoma
Recruiting NCT07365319
A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.
Non Small Cell Lung Cancer (Squamous or Non Squamous) · Stage 4 NSCLC
Not yet recruiting NCT06941480
A Study of 177Lu-DTPA-SC16.56 in People With Neuroendocrine Carcinomas of the Lung and Prostate
Neuroendocrine Tumor of the Lung · Neuroendocrine Carcinoma of Lung · Neuroendocrine Carcinoma
Recruiting NCT07286149
A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)
Lung Neoplasm Malignant
Recruiting NCT05401110
Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer
Non Small Cell Lung Cancer · Lung Cancer
Recruiting NCT07705334
A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors
Advanced or Metastatic Solid Tumors · Triple Negative Breast Cancer (TNBC) · HR+ Breast Cancer
Recruiting NCT04151940
PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer
Metastatic Lung Non-Small Cell Carcinoma · Recurrent Lung Non-Small Cell Carcinoma · Stage IV Lung Cancer AJCC v8
Not yet recruiting NCT07750704
Lorlatinib Plus Sacituzumab Tirumotecan With Peripheral ctDNA Guidance as First-Line Therapy for ALK Fusion-Positive NSCLC
ALK Positive Non-small Cell Lung Cancer
Recruiting NCT06862869
Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy
Carcinoma, Non-Small-Cell Lung
Recruiting NCT07408531
LUNG-07: Advancing Precision-Based Lung Cancer Screening: Implementation, AI-Guided Risk Stratification, and Biomarker Integration (CREST AI)
Lung Cancer Screening
Recruiting NCT06806592
A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases
Interstitial Lung Diseases · Systemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases
Recruiting NCT07217171
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
Bladder Cancer · Squamous Cell Carcinoma of the Lung · Esophageal Squamous Cell Carcinoma
Recruiting NCT07201922
A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis
Familial Pulmonary Fibrosis · Interstitial Lung Abnormalities · Interstitial Lung Diseases
Recruiting NCT07745881
Analgesic Effects of Retro-superior Costotransverse Ligament Space Block for Video-assisted Thoracoscopic Surgery
Nerve Block · Thoracoscopic Radical Resection of Lung Cancer
Recruiting NCT06096844
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
Advanced Lung Non-Small Cell Carcinoma · Stage IIIB Lung Cancer AJCC v8 · Stage IIIC Lung Cancer AJCC v8
Recruiting NCT07365241
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
Small Cell Lung Cancer
Not yet recruiting NCT07743723
A Study of IOV-5001 in Adults With Advanced Solid Tumors
Advanced Solid Tumors · Non-Small Cell Lung Cancer · Triple Negative Breast Cancer (TNBC)
Enrolling by invitation NCT05627674
Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment
Smoking · Smoking Cessation · Tobacco Use Cessation
Recruiting NCT07127874
A Study of PHN-012 in Patients With Advanced Solid Tumors
Colon Cancer · Pancreatic Cancer · Lung Cancer (NSCLC)
Recruiting NCT06406777
Chronic Lung Allograft Dysfunction MRI Study
Chronic Lung Allograft Dysfunction Lung MRI (CLAD)
Recruiting NCT05920356
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Non-Small Cell Lung Cancer (NSCLC)
Not yet recruiting NCT07540988
FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression
Interstitial Lung Diseases
Recruiting NCT06634056
Pneumonitis Prevention Protocol Using Pentoxifylline and α-tocopherol In Stage III Non-Small Cell Lung Cancer Patients Undergoing Chemoradiation
Non-Small Cell Lung Cancer · Radiation Induced Lung Injury (RILI)
Recruiting NCT06287775
Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer
Extensive Stage Lung Small Cell Carcinoma · Stage IV Lung Cancer AJCC v8
Recruiting NCT05198830
Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer
Lung Adenocarcinoma · Lung Large Cell Carcinoma · Lung Non-Squamous Non-Small Cell Carcinoma
Recruiting NCT07227168
A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
Head and Neck Squamous Cell Carcinoma HNSCC · Non-Small Cell Lung Cancer NSCLC · Esophageal Cancer
Not yet recruiting NCT07747805
GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD
COPD · Obesity & Overweight · Sarcopenia
Recruiting NCT06473961
A Phase Ib Study of GC101 in NSCLC
Non Small Cell Lung Cancer Metastatic · Non Small Cell Lung Cancer
Recruiting NCT06632327
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer
Resectable Lung Non-Small Cell Carcinoma · Stage II Lung Cancer AJCC v8 · Stage IIIA Lung Cancer AJCC v8
Recruiting NCT06498635
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Lung Non-Small Cell Carcinoma · Stage II Lung Cancer AJCC v8 · Stage IIIA Lung Cancer AJCC v8
Recruiting NCT06449313
Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node or Other High Risk Features
Non-small Cell Lung Cancer Stage III
Recruiting NCT07748325
Adjuvant Immune Checkpoint Inhibitor Versus Observation After Neoadjuvant Immunochemotherapy and Surgery in High-Risk NSCLC
Non-Small Cell Lung Cancer · Adjuvant Therapy · Immune Checkpoint Inhibitors
Recruiting NCT04613596
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Advanced Non-Small Cell Lung Cancer · Metastatic Non-Small Cell Lung Cancer
Recruiting NCT07560111
A Phase II Study of GC101 in NSCLC
Non Small Cell Lung Cancer
Recruiting NCT06910657
IDOV-Immune for Advanced Solid Tumors
Colorectal Cancer · Pancreatic Cancer · Melanoma
Recruiting NCT07412041
Precise Exercise Regimen for Cancer Care (PERCC): A Pilot Study
Stage II Lung Cancer · Lung Cancer · Non-small Cell Lung Cancer
Recruiting NCT07483983
Study Investigating ASP3082 in Patients With Metastatic/Locally Advanced Non-small-cell Lung Cancer (NSCLC) and Pancreatic Ductal Adenocarcinoma (PDAC), With Biomarker Analysis to Characterize Response/Resistance
Metastatic/Locally Advanced Non-Small-Cell Lung Cancer · Metastatic/Locally Pancreatic Ductal Adenocarcinoma
Recruiting NCT05176483
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Renal Cell Carcinoma (RCC) · Metastatic Castration-Resistant Prostate Cancer (mCRPC) · Urothelial Carcinoma (UC)
Recruiting NCT06706076
A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations
NSCLC (Advanced Non-small Cell Lung Cancer)
Recruiting NCT07357597
An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.
Stomatitis
Recruiting NCT07277413
A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
NSCLC Adenocarcinoma · Gastroesophageal Cancer (GC) · Gastric Adenocarcinoma
Recruiting NCT07444814
Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors
Endometrial Cancer · Ovarian Cancer · Ovarian Cancer Metastatic
Recruiting NCT07746323
Effect of Modified Arm Positioning on Shoulder Pain After Thoracoscopic Lobectomy
Ipsilateral Shoulder Pain · Lung Neoplasms
Recruiting NCT06014827
Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) to Tyrosine Kinase Inhibitor in Oligoprogressive Oncogenic Positive Non-Small Cell Lung Carcinoma
Lung Non-Small Cell Carcinoma · Stage IV Lung Cancer AJCC v8
Recruiting NCT07293247
A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment
Lung Non-Small Cell Carcinoma
Recruiting NCT07111520
A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer
Recruiting NCT07059884
Distance-Based Exercise to Preserve Function and Prevent Disability
Localized Malignant Solid Neoplasm · Anal Cancer · Bladder (Urothelial, Transitional Cell) Cancer
Recruiting NCT07744334
Effect of Aerobic and Resistance Exercise on Quarry Workers
Ventilatory Defect · Occupational Lung Diseases · Respiratory Disorders
Recruiting NCT06465069
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Metastatic Solid Tumor · Recurrent Solid Tumor · Advanced Solid Tumor
Not yet recruiting NCT07707895
DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine Cancers
Small Cell Lung Cancer · Large Cell Neuroendocrine Lung Carcinoma · Extrapulmonary Neuroendocrine Carcinoma of Small Cell Histology
Recruiting NCT07747337
Respiratory, Limb Muscle Properties, and Physical Performance in Adult Lung Transplant Recipients
Lung Transplantation · End Stage Lung Disease
Recruiting NCT04999761
AB122 Platform Study
Advanced or Metastatic Solid Tumor · Pancreatic Ductal Adenocarcinoma · Colorectal Cancer
Recruiting NCT05654922
Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant
Pre-Bronchiolitis Obliterans Syndrome
Not yet recruiting NCT07468656
SCLC Tarlatamab Blood Collection
Small-cell Lung Cancer