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Not yet recruiting NCT07518888

Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer

No phase Interventional Prostate Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: High-Intensity Interval Training (HIIT) Exercise.
Who it may be relevant to
Registry conditions: Prostate Cancer. Basic parameters: 18 years — 80 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The purpose of this research study is to understand how a short session of a home-based bodyweight high-intensity interval training (HIIT) affects steroid hormone levels in men on active surveillance for low-grade prostate cancer.

Interventions

  • Behavioral High-Intensity Interval Training (HIIT) Exercise
    Participants will complete a single supervised, online high intensity interval training (HIIT) exercise session lasting approximately 20 minutes. The exercise protocol consists of six 1-minute bouts with 1-minute rest intervals of moderate to high intensity bodyweight exercises, including movements such as lateral squats, wall pushups, and chair assisted sit to stands.

Primary outcome measures

  • Protocol Completion Rate [Time frame: From enrollment through completion of all study procedures (up to Day 1)]
Secondary outcome measures (1)
  • Acceptability of the Exercise and Saliva Collection Protocol [Time frame: Immediately after protocol completion (Day 1)]

Eligibility criteria

Inclusion criteria

  • Males 18 to 80 years old
  • Diagnosis of localized prostate cancer
  • Currently under active surveillance
  • Ability to perform moderate-to-high intensity physical activity as demonstrated by self-assessment using the Physical Activity Readiness Questionnaire (PAR-Q+)
  • Able to independently perform activities of daily living, without limitations in mobility
  • Ability to read, write, speak, and understand English
  • Able and willing to sign consent and comply with study requirements

Exclusion criteria

  • Males currently receiving treatment for prostate cancer
  • Diagnosis of metastatic prostate cancer
  • Individuals with medical conditions contraindicating exercise
  • Uncontrolled cardiovascular or circulatory diseases, hypertension, and diabetes, as determined by the study doctor or treating physician
  • Ongoing use of medications affecting steroid metabolism
  • Unable to sign consent and/or comply with study requirements

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Basic science

Study locations

United States · 1 center
  • University of Miami Hospitals and Clinics — Miami

Identifiers

NCT: NCT07518888 · 20251282

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗