An AI-Based Erythema Measurement System for Psoriasis Lesions
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: No additional drugs(control Group).
- Who it may be relevant to
- Registry conditions: Psoriasis. Basic parameters: 18 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Thailand
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Development and Validation of an AI-Based Erythema Measurement System for Psoriasis Lesions Using Smartphone Imaging With Color Card Compared to Standard Color Calibration Device
Overview
Psoriasis is a common chronic inflammatory skin disease. Disease severity is commonly assessed using the Psoriasis Area and Severity Index (PASI), in which erythema is graded subjectively on a 0-4 scale. This visual assessment is prone to significant inter- and intra-rater variability. Although objective tools such as colorimeters provide accurate erythema measurement, their high cost limits routine clinical use. Smartphone imaging combined with artificial intelligence (AI) offers a practical alternative for objective assessment. However, variability in lighting conditions can affect image consistency. Incorporating a color calibration card enables accurate color normalization. This study aims to develop and validate an AI-based system for measuring erythema in psoriatic lesions using smartphone images with a color card, compared against a standard colorimeter to assess validity and reliability.
Interventions
- Diagnostic test No additional drugs(control Group)
This study is distinct from other clinical studies in that it does not involve any therapeutic intervention or modification of standard patient care. Instead, it evaluates a non-invasive, image-based measurement system that combines smartphone photography, a color calibration card, and artificial intelligence to quantify erythema in psoriasis lesions. Unlike conventional approaches that rely on subjective physician scoring or require specialized and costly equipment, this intervention is designe
Primary outcome measures
- To evaluate the accuracy of erythema measurements of psoriatic lesions obtained from an AI-based erythema model (smartphone imaging with a color calibration card) compared with a standard color calibration device (gold standard). [Time frame: From enrollment to 12 weeks]
Eligibility criteria
Inclusion criteria
- Adults aged ≥18 years
- Diagnosed with psoriasis by a dermatologist
- Presence of at least five clearly photographable lesions
- Willing and able to take photographs using a smartphone with both a standard color calibration card and a study-specific color card at home weekly, and submit images via Line or email
- Willing to have clinical photographs taken at baseline and at a follow-up visit
- Provides written informed consent to participate in the study
Exclusion criteria
- Presence of skin infection or other lesions that may interfere with color assessment (e.g., tattoos)
- Use of self-tanning products or substances that alter skin color
- Inability to perform photography or comply with study procedures
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
Thailand · 1 center
- Khon Kaen University — Khon Kaen
Identifiers
NCT: NCT07494396 · HE694001