Validity and Reliability of Timed Up and Go Test in Dual-Task Conditions for Multiple Sclerosis Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Multiple Sclerosis, Reliability and Validity, Dual Task. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Validity and Reliability of Timed Up and Go Test in Dual-Task Conditions in Patients With Multiple Sclerosis
Overview
his study aims to examine the validity and reliability of the Timed Up and Go (TUG) test in patients with Multiple Sclerosis (MS) under dual-task conditions, where participants perform both a motor and a cognitive task at the same time. MS affects movement, balance, and cognitive functions, which can lead to difficulties in walking and increased risk of falls. In this study, volunteers with MS will be asked to perform the TUG test in different conditions: Single-task TUG: walking, standing up, and sitting down without additional tasks. Cognitive dual-task TUG: performing TUG while doing a cognitive task, such as counting backwards or word generation. Motor dual-task TUG: performing TUG while carrying a small object on a tray. Participants' demographic and clinical information will be recorded, and tests will be repeated to evaluate the reliability of the measurements. The results will help determine if the TUG test can reliably assess both motor and cognitive performance in MS patients. The study is observational, and no experimental treatment will be given. Participation involves only performing tests and answering questions, taking approximately 25-30 minutes per session. All collected data will be kept confidential.
Detailed description
This study investigates the validity and reliability of the Timed Up and Go (TUG) test under dual-task conditions in patients with Multiple Sclerosis (MS). MS is a chronic neurological disease that affects motor and cognitive functions, often leading to walking difficulties, balance problems, and increased risk of falls.
Volunteers with MS will be recruited from the Neurological Rehabilitation Unit at SANKO University. Eligible participants will perform the TUG test in three conditions:
Single-task TUG: normal TUG without additional tasks.
Cognitive dual-task TUG (kSKYT): performing TUG while counting backwards in threes or generating words starting with a specific letter.
Motor dual-task TUG (mSKYT): performing TUG while carrying a small ball on a tray.
Participants' demographic and clinical data, including age, sex, height, weight, MS duration, EDSS score, and history of falls, will be recorded. TUG tests will be conducted by two physiotherapists and repeated after one week to assess test-retest reliability and inter-rater reliability.
Convergent validity will be evaluated by comparing dual-task TUG results with single-task TUG, 25-step walking test, Mini-BESTest, and a dual-task questionnaire. Known-groups validity will be assessed by comparing results between MS patients who have fallen and those who have not.
All data will be coded and stored confidentially. The study is observational, with no experimental interventions, and each assessment session will take approximately 25-30 minutes.
Primary outcome measures
- Sit-to-Stand and Walk Test (SKYT) [Time frame: 1 week]
- Dual-task SKYT tests [Time frame: one weeks]
- The 25-step walk test (S25AYT) [Time frame: one weeks]
- Dual-task questionnaire [Time frame: one weeks]
- Mini-BESTest [Time frame: one weeks]
Eligibility criteria
Inclusion criteria
- Diagnosed with Multiple Sclerosis (MS).
- Age 18 years or older.
- EDSS score low to moderate (able to walk without assistive devices).
- Willing to provide informed consent.
- Able to perform Timed Up and Go (TUG) test.
Exclusion criteria
- Severe cognitive impairment preventing understanding of instructions.
- Recent MS relapse (within the past 30 days).
- Use of walking aids that interfere with TUG test performance.
- Other neurological or musculoskeletal conditions affecting walking or balance.
- Any condition that makes participation unsafe, according to the investigato
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
Turkey (Türkiye) · 1 center
- Sanko Unıversıty — Gaziantep
Identifiers
NCT: NCT07462338 · hakanpolat16