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Recruiting NCT07461090

Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis

No phase Interventional Nonfunctioning Kidney Renal Cell Carcinoma (RCC)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: open or laparoscopic nephrectomy.
Who it may be relevant to
Registry conditions: Nonfunctioning Kidney, Renal Cell Carcinoma (RCC). Basic parameters: from 1 year · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .

Interventions

  • Procedure open or laparoscopic nephrectomy
    compare post operative recovery , estimated blood loss and cost analysis between open and laparosopic nephrectomy.

Primary outcome measures

  • Length of hospital stay (LOS). [Time frame: 30 days post operative]
Secondary outcome measures (1)
  • clinical effectiveness [Time frame: Post operative 30 days.]

Eligibility criteria

Inclusion criteria

  • American Society of Anesthesiology score 1-3.
  • Indication for :
  • Simple total nephrectomy or hemi nephrectomy: benign chronic inflammatory non-functioning kidney
  • Partial nephrectomy: localized renal mass ≤7 cm suitable for nephron-sparing surgery.
  • Radical nephrectomy or Radical nephrouretrectomy with bladder cuff: localized renal tumor requiring complete nephrectomy without major vascular invasion.
  • Patient deemed fit for general anesthesia and surgery.
  • Patient provides written informed consent.

Exclusion criteria

  • emergency surgery, dialysis-dependent patients, planned hybrid procedures.
  • Patients with incomplete data
  • Patients with metastatic disease at presentation.
  • Prior extensive ipsilateral retroperitoneal surgery or severe adhesions precluding Laparoscopy.
  • Need for concomitant major procedures (eg, large bowel resection) at index operation.
  • Locally advanced tumor with obvious major vascular involvement requiring complex vascular reconstruction.
  • Uncorrected coagulopathy.
  • Pregnancy or Obese patient (BMI > 40)
  • Inability to provide informed consent or comply with follow-up.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Menoufia Faculty of Medicine — Shibīn al Kawm

Identifiers

NCT: NCT07461090 · laparoscopic nephrectomy

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗