Not yet recruiting NCT07460583
ProActive Athlete Heart Program: Proposal for Cardiac Risk Screening in Former High-Intensity Athletes
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Coronary CTA.
- Who it may be relevant to
- Registry conditions: Coronary Atherosclerosis Due to Calcified Coronary Lesion. Basic parameters: from 30 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
AI-Guided Coronary CT Angiography Screening in Former High-Intensity Athletes
Detailed description
A prospective, interventional, single-center study to determine the prevalence and characteristics (burden, composition, risk features) of coronary atherosclerosis in former high-intensity athletes using AI-guided software to analyze a CCTA.
Interventions
- Device Coronary CTA
The Coronary CTA will be performed for each participant. These images will be analyzed using AI-software to assess plaque quantification and an ischemia analysis, if necessary.
Primary outcome measures
- Prevalence of Coronary Atherosclerosis [Time frame: At CCTA assessment]
- Coronary Atherosclerosis Characteristics [Time frame: At CCTA Assessment]
Secondary outcome measures (1)
- Plaque Burden [Time frame: Day of CCTA and biomarker collection]
Eligibility criteria
Inclusion criteria
- Former professional or collegiate high-intensity athletes (e.g., NFL alumni, Division I athletes, or equivalent competitive-level participants).
- Age ≥30 years
Exclusion criteria
- eGFR <40 mL/min/1.73 m²
- Known iodinated contrast allergy
- Weight >450 lbs. (scanner table limit)
- Inability to hold breath >10 seconds
- Uncontrolled arrhythmia
- Contraindication to beta-blocker, Calcium Channel Blockers and nitroglycerin
- Taking part in another research study that has not given their permission to participate in this one
- Pregnancy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Screening
Study locations
United States · 1 center
- Baylor Scott & White The Heart Hospital- Plano — Plano
Identifiers
NCT: NCT07460583 · 026-123