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Recruiting NCT07435168

CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis

No phase Interventional Cardiac Amyloidosis Chest Pain

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Screening thourgh examinations including bonescintigraphy.
Who it may be relevant to
Registry conditions: Cardiac Amyloidosis, Chest Pain. Basic parameters: from 65 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Denmark
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD). Prior to inclusion, all patients will have undergone a CT coronary angiogram or an Rb-PET scan to rule out the possibility of CAD. Participants will be subject to several examinations, including blood tests, urine samples, ECG, echocardiography, and bone scintigraphy. An endomyocardial biopsy may be conducted if necessary.

Interventions

  • Other Screening thourgh examinations including bonescintigraphy
    Clinical examination, blood samples, echo, bone scintigraphy

Primary outcome measures

  • Prevalence of ATTR-CA in patients experiencing chest pain [Time frame: Up to 4 weeks]

Eligibility criteria

Inclusion criteria

No signs of CAD through Rb-PET and/or CT coronary arteriogram

Exclusion criteria

Previous history of amyloidosis

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Screening

Study locations

Denmark · 1 center
  • Rigshospitalet — Copenhagen

Identifiers

NCT: NCT07435168 · H-24002324

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗