Hematology

Recruiting NCT06136559☆ Save

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Phase III Interventional United States, Australia +27

Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma

Recruiting NCT07751783☆ Save

Development and Dissemination of Exercise Prescription and Intervention for Cancer Populations

No phase Interventional Taiwan

Cancer · Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma) · Lung Cancer (Non-Small Cell)

Recruiting NCT07437950☆ Save

Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Phase II Interventional United States, Puerto Rico

Acute Myeloid Leukemia

Not yet recruiting NCT07751471☆ Save

BCMA/GPRC5D Trispecific Antibody Treatment for Newly Diagnosed Amyloidosis (AL-004)

Phase II Interventional China

AL Amyloidosis

Recruiting NCT07634471☆ Save

A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007)

Phase II / Phase III Interventional United States, Argentina +4

Follicular Lymphoma

Recruiting NCT06904066☆ Save

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

Phase I Interventional United States

Malignancy, Hematologic · Neoplasms, Hematologic · Neoplasms, Hematopoietic

Recruiting NCT00027274☆ Save

Cancer in Inherited Bone Marrow Failure Syndromes

— Observational United States

Diamond Blackfan Anemia · Dyskeratosis Congenita · Fanconi Anemia

Recruiting NCT06890884☆ Save

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Phase II Interventional United States, Belgium +7

Lymphoma, Large B-Cell, Diffuse

Recruiting NCT04269902☆ Save

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Phase III Interventional United States, Canada

Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma

Recruiting NCT05092451☆ Save

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

Phase I / Phase II Interventional United States

B-Cell Lymphoma · Myelodysplastic Syndromes (MDS) · Acute Myeloid Leukemia (AML)

Not yet recruiting NCT07524530☆ Save

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Phase II Interventional United States

Core Binding Factor Alpha Subunits · Hematologic Neoplasms · Leukemia

Recruiting NCT06649812☆ Save

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Phase II Interventional United States

High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements · Recurrent Diffuse Large B-Cell Lymphoma · Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type

Recruiting NCT07751991☆ Save

A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML

Phase I Interventional United States

AML (Acute Myeloid Leukemia)

Recruiting NCT05947851☆ Save

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

Phase III Interventional United States, Argentina +16

Leukemia, Lymphocytic, Chronic, B-Cell · Leukemia, Chronic Lymphocytic · Small-Cell Lymphoma

Recruiting NCT06744504☆ Save

Standard-dose vs Intermediate-dose Cytarabine Induction in the Treatment of Acute Myeloid Leukemia With RUNX1-RUNX1T1

Phase III Interventional China

AML · RUNX1-RUNX1T1 Fusion Protein Expression

Not yet recruiting NCT07753148☆ Save

Safety and Tolerability of REGN17235 in Adult Participants With Clonal Cytopenia of Undetermined Significance and Low-Risk Myelodysplastic Syndrome With SF3B1 Mutation

Phase I Interventional —

Clonal Cytopenia of Undetermined Significance (CCUS) · Low-Risk Myelodysplastic Syndrome (LR-MDS)

Enrolling by invitation NCT00001620☆ Save

Screening for Hematology Branch Protocols

— Observational United States

Hematologic Disease and Disorders · Donors · Healthy Volunteer

Recruiting NCT06303193☆ Save

Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

Phase I / Phase II Interventional United States

Myelodysplastic Syndromes

Not yet recruiting NCT07752121☆ Save

First-Line Luspatercept in Transfusion-Dependent Lower-Risk Myelodysplastic Neoplasms

— Observational Germany

Myelodysplastic Neoplasms

Recruiting NCT03618550☆ Save

Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma

Phase II Interventional United States

Hodgkin Lymphoma · Relapsed or Refractory Hodgkin Lymphoma

Recruiting NCT03854318☆ Save

Longitudinal Studies of Patient With FPDMM

— Observational United States

Inherited Hematological Diseases · Rare Diseases · FPDMM

Recruiting NCT03269578☆ Save

Sample Collection and Tracking for the Developmental Therapeutics Clinic

— Observational United States

Neoplasms · Lymphoma

Recruiting NCT05012111☆ Save

Natural History of Acquired and Inherited Bone Marrow Failure Syndromes

— Observational United States

Severe Aplastic Anemia · Telomere Biology Disorders · Inherited Bone Marrow Failure Syndromes

Recruiting NCT07269470☆ Save

Phase II Study Assessing the Safety and Efficacy of Dasatinib in Combination With Ropeginterferon in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

Phase II Interventional United States

Chronic Myeloid Leukemia

Recruiting NCT05675410☆ Save

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Phase III Interventional United States, Canada +1

Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Recruiting NCT05724121☆ Save

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

— Observational United States

Chronic Lymphocytic Leukemia (CLL) · Waldenstr(SqrRoot)(Delta)m s Macroglobulinemia · Mantle Cell Lymphoma

Recruiting NCT05632380☆ Save

ASCT in Combination With C-CAR088 for Treating Patients With Ultra High-risk Multiple Myeloma (MM)

Phase I / Phase II Interventional China

Multiple Myeloma

Enrolling by invitation NCT00071045☆ Save

Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members

— Observational United States

Neoplasms · Hematologic Neoplasms · Healthy Volunteers

Recruiting NCT06337318☆ Save

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Phase III Interventional United States

Classic Follicular Lymphoma · Follicular Lymphoma With Unusual Cytological Features

Recruiting NCT04728893☆ Save

Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

Phase II Interventional United States, Argentina +20

Hematologic Malignancies · Waldenstroms Macroglobulinaemia · Non-Hodgkins Lymphoma

Recruiting NCT07629726☆ Save

A Phase 1/2 Study of KK2430 in Participants With Hematologic Neoplasms

Phase I / Phase II Interventional United States

Hematologic Neoplasms

Not yet recruiting NCT07753642☆ Save

Golidocitinib Plus Anthracycline-based Therapy for Untreated Nodal T-follicular Helper (TFH) Cell Lymphoma

Phase II Interventional China

Nodal T-follicular Helper Cell Lymphoma

Recruiting NCT06973811☆ Save

ZR-MTX for PIOL Phase II Trial

Phase II Interventional China

Primary Intraocular Lymphoma

Recruiting NCT03173937☆ Save

Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Phase I / Phase II Interventional United States

Severe Aplastic Anemia · Hypo-Plastic MDS · Myelodysplastic Syndrome (MDS)

Recruiting NCT02390752☆ Save

Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...

Phase I Interventional United States

Neurofibroma, Plexiform · Precursor Cell Lymphoblastic Leukemia-Lymphoma · Leukemia, Promyelocytic, Acute

Not yet recruiting NCT07751588☆ Save

Plasma ctDNA Monitoring in Pediatric Acute Leukemia

— Observational China

Acute Myeloid Leukemia · Acute Lymphoblastic Leukemia

Recruiting NCT06846671☆ Save

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

Phase III Interventional United States, Argentina +12

CLL · Chronic Lymphocytic Leukemia

Recruiting NCT06317662☆ Save

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Phase II Interventional United States, Puerto Rico

Acute Leukemia of Ambiguous Lineage · B Acute Lymphoblastic Leukemia

Recruiting NCT05139017☆ Save

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

Phase II / Phase III Interventional United States, Argentina +24

DLBCL · Diffuse Large B-Cell Lymphoma

Recruiting NCT07409454☆ Save

MRD-Guided BCMA/CD3 Bispecific Antibody Treatment After Stem Cell Transplant for Newly Diagnosed Multiple Myeloma

Phase II Interventional China

Multiple Myeloma

Recruiting NCT04002947☆ Save

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

Phase II Interventional United States

Non-Hodgkin's Lymphoma · Diffuse Large B-Cell Lymphoma · DLBCL

Recruiting NCT04973605☆ Save

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

Phase I / Phase II Interventional United States, Australia +11

Relapsed/Refractory Multiple Myeloma

Enrolling by invitation NCT07328516☆ Save

Natural History Study of Early Life Exposures in Agriculture (ELEA)

— Observational United States

Prostate Cancer · Leukemia · Breast Cancer

Recruiting NCT03223610☆ Save

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Phase I / Phase II Interventional United States

Lymphoma · Non-Hodgkin Lymphoma · Diffuse Large B-Cell Lymphoma

Recruiting NCT07570173☆ Save

A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)

Phase II / Phase III Interventional Denmark, Greece +5

B-cell Acute Lymphoblastic Leukemia

Recruiting NCT05470491☆ Save

Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

Phase I / Phase II Interventional United States

HIV · Hematologic Malignancies

Recruiting NCT06311227☆ Save

Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia

Phase II Interventional United States

Recurrent Hairy Cell Leukemia · Recurrent Hairy Cell Leukemia Variant

Recruiting NCT06980480☆ Save

A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma

Phase III Interventional United States, Australia +13

Multiple Myeloma · Secondary Immunodeficiency

Recruiting NCT06265545☆ Save

Multicenter, Platform-type Clinical Study of Refractory/Recurrent Acute Myeloid Leukemia

No phase Interventional China

AML · Refractory · Relapsed

Recruiting NCT07393282☆ Save

A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM)

Phase III Interventional United States

High Risk Smoldering Multiple Myeloma (HR-SMM)

Recruiting NCT07061145☆ Save

A Potential Relationship Between Treatment With Tyrosine Kinase Inhibitors and Erectile Dysfunction in Male Patients With Chronic Myeloid Leukemia

— Observational Italy

Chronic Myelocytic Leukemia · Erectile Dysfunctions · CVD - Cardiovascular Disease

Recruiting NCT00001529☆ Save

Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives

— Observational United States

Graft-Versus-Host Disease · Graft-versus-leukemia · Donor Apheresis

Recruiting NCT00006518☆ Save

Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer

— Observational United States

HIV · Kaposi's Sarcoma · Lymphomas

Recruiting NCT06103838☆ Save

18F-Fluciclovine PET/CT in Multiple Myeloma

Phase II Interventional United States

Multiple Myeloma · Newly Diagnosed Multiple Myeloma (NDMM) · Relapsed and/or Refractory Multiple Myeloma (RRMM)

Not yet recruiting NCT07753369☆ Save

A Clinical Trial to Evaluate the Efficacy and Safety of TQB3909 Tablets Versus Investigator's Choice in the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Phase III Interventional China

Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Recruiting NCT06066359☆ Save

Ph I/II Trial of Cord Blood-derived NK Cells With NY-ESO-1 TCR/IL-15 for R/R Myeloma

Phase I / Phase II Interventional United States

Relapsed/Refractory Myeloma

Recruiting NCT07752732☆ Save

Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With Higher-Grade Aortic Valve Stenosis - Evaluation Using Echocardiography, Computed Tomography, Tc99-SPECT/CT and Cardiac Magnetic Resonance Imaging (CMR)

— Observational Germany

Amyloidosis Cardiac · Stenosis Coronary · TAVI(Transcatheter Aortic Valve Implantation)

Recruiting NCT07519772☆ Save

A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)

Phase I / Phase II Interventional United States, Argentina +9

Lymphoma, Non-Hodgkin · Lymphoma, Follicular · Lymphoma, Large B-Cell, Diffuse

Recruiting NCT07661537☆ Save

A Clinical Study of SHR-3079 in B-cell Non-Hodgkin Lymphoma

Phase I Interventional China

B-cell Non-Hodgkin Lymphoma

Not yet recruiting NCT07744750☆ Save

Pirtobrutinib+Sonrotoclax（PS) Regimen in the Treatment of B-Cell Lymphoma

Phase II Interventional China

DLBCL - Diffuse Large B Cell Lymphoma · Richter Transformation · CLL / SLL

Not yet recruiting NCT07597590☆ Save

Digital Patient-Reported Assessment in Older Adults With Acute Leukemia

No phase Interventional Spain

Leukemia Acute Myeloid · Leukemia Acute Lymphoid Leukemia (ALL)

Recruiting NCT06091865☆ Save

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

Phase III Interventional United States, Australia +18

Diffuse Large B-cell Lymphoma (DLBCL)

Not yet recruiting NCT07736950☆ Save

A Study Comparing a New Drug (Surovatamig) With Standard Radiotherapy With or Without Rituximab in Adults With Limited Stage Nodal Follicular Lymphoma

Phase III Interventional —

Follicular Lymphoma

Recruiting NCT06670222☆ Save

Oral Arsenic (ATO) in Low-risk Myelodysplastic Syndromes (MDS)

Phase I Interventional France

Low-risk Myelodysplastic Syndromes

Recruiting NCT07195916☆ Save

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

Phase I Interventional United States, Australia +3

Solid Tumors · Hematologic Malignancies

Recruiting NCT07284758☆ Save

A Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

Phase II Interventional United States, United Kingdom

Multiple Myeloma · Relapsed/Refractory Multiple Myeloma

Recruiting NCT07493304☆ Save

Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers

Phase III Interventional United States, South Korea

Venous Thromboembolism (VTE)

Recruiting NCT05006716☆ Save

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

Phase I / Phase II Interventional United States, Australia +14

B-cell Malignancy · Marginal Zone Lymphoma · Follicular Lymphoma

Recruiting NCT07200375☆ Save

An Observational Study of Glofitamab in Chinese Adult Participants With 2L Diffuse Large B-Cell Lymphoma

— Observational China, Hong Kong

Diffuse Large B-Cell Lymphoma

Recruiting NCT07425782☆ Save

Venetoclax Combined With Azacitidine for Consolidation Therapy in AML

Phase II Interventional China

Acute Myeloid Leukemia · Consolidation Therapy · Venentoclax

Recruiting NCT06600568☆ Save

Novel Therapeutic Approach for Human T-cell Malignancies

— Observational Italy

T-Cell Leukemia/Lymphoma, Adult

Recruiting NCT06533579☆ Save

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

Phase I / Phase II Interventional United States

B-cell Acute Lymphoblastic Leukemia · Large B-cell Lymphoma · Chronic Lymphocytic Leukemia

Recruiting NCT07218341☆ Save

A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Phase IV Interventional United States, Australia +14

Chronic Lymphocytic Leukemia · Lymphoma, Small Lymphocytic

Recruiting NCT07749365☆ Save

Hypofractionated Radiotherapy Plus GM-CSF, Pomalidomide and Glofitamab for Newly Diagnosed PCNS-DLBCL

Phase II Interventional China

DLBCL - Diffuse Large B Cell Lymphoma · PCNSL (Primary CNS Lymphoma)

Recruiting NCT07226843☆ Save

A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

Phase I Interventional United States, France +6

Lymphoma, Non-Hodgkin's · Lymphoma, Diffuse Large B-Cell · Follicular Lymphoma

Recruiting NCT04077307☆ Save

A Study in Leukemia Patients With Karonudib

Phase I Interventional Denmark, Serbia +1

Leukemia

Recruiting NCT07277231☆ Save

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Phase III Interventional United States, Australia +15

Chronic Lymphocytic Leukemia

Recruiting NCT06090864☆ Save

ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells

Phase I / Phase II Interventional United States

Hodgkin Lymphoma · Relapse · Refractory

Not yet recruiting NCT07518329☆ Save

Study of ALA-101 in Patients With CD19 Positive Non-Hodgkin Lymphoma and Leukemia.

Phase I Interventional Australia

Non Hodgkin Lymphoma (NHL) · Leukaemia

Recruiting NCT07024706☆ Save

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

Phase II Interventional United States, Austria +6

Chronic Lymphocytic Leukemia (CLL) · Small Lymphocytic Lymphoma (SLL)

Recruiting NCT06934044☆ Save

A Study Evaluating the Pharmacokinetics, Safety, and Efficacy of Cevostamab in Chinese Participants With Relapsed or Refractory Multiple Myeloma

Phase I Interventional China

Multiple Myeloma

Recruiting NCT07223814☆ Save

Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

Phase III Interventional United States, Australia +7

Acute Myeloid Leukemia

Not yet recruiting NCT07744737☆ Save

Pirtobrutinib + R-CHOP for Untreated Non-GCB DLBCL

Phase II Interventional China

DLBCL - Diffuse Large B Cell Lymphoma · R-CHOP Chemotherapy · Pirtobrutinib

Not yet recruiting NCT07748689☆ Save

Comparing Lower Versus Standard Doses of Belantamab Mafodotin With Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma.

Phase II Interventional —

Relapsed / Refractory Multiple Myeloma

Recruiting NCT07670130☆ Save

Venetoclax TDM in Newly Diagnosed AML: Exposure-Response and Prognosis

— Observational China

Acute Myeloid Leukemia (AML)

Recruiting NCT05976763☆ Save

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

Phase III Interventional United States

Mantle Cell Lymphoma

Not yet recruiting NCT07743047☆ Save

Harnessing the Immunosuppressive Leukemic Microenvironment to Engineer T Cells With Enhanced Anti-tumor Functionality

— Observational —

Acute Myeloid Leukemia

Enrolling by invitation NCT05600933☆ Save

Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment

— Observational United States

Solid Tumors · Hematologic Malignancy · Gastrointestinal Cancer

Recruiting NCT05952024☆ Save

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

Phase II Interventional United States, Brazil +3

Diffuse Large B-Cell Lymphoma

Recruiting NCT04628026☆ Save

Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2

Phase III Interventional Austria, Belgium +6

Acute Myeloid Leukemia

Recruiting NCT06483100☆ Save

Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance

Phase II Interventional United States

Multiple Myeloma

Not yet recruiting NCT07570056☆ Save

Use of Electrical Bioimpedance in Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patients (Bioimpedance)

— Observational —

Myelodysplastic Syndromes · Acute Myeloid Leukemia

Recruiting NCT07750886☆ Save

Sample Collection for Ongoing Research and Product Evaluation Study - Non-Hodgkin Lymphoma (SCORE-NHL)

— Observational United States

Non-Hodgkin Lymphoma · T-Cell Lymphoma · Diffuse Large B-Cell Lymphoma

Recruiting NCT07672262☆ Save

VA Consolidation in Intermediate-Risk AML

Phase II Interventional China

Acute Myeloid Leukemia · Intermediate Risk Acute Myeloid Leukemia · Consolidation Therapy

Recruiting NCT06973187☆ Save

A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Phase III Interventional United States, Argentina +22

Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma

Recruiting NCT07332507☆ Save

Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma

Phase I Interventional United States

Recurrent Plasmablastic Lymphoma · Refractory Plasmablastic Lymphoma

Recruiting NCT07463807☆ Save

Testing the Investigational Medication Combination of Teclistamab and Pomalidomide Compared to the Usual Treatment (Carfilzomib, Pomalidomide, and Dexamethasone) for Patients With Multiple Myeloma Who Have Relapsed Shortly After Treatment

Phase I / Phase II Interventional United States

Recurrent Multiple Myeloma · Refractory Multiple Myeloma

Not yet recruiting NCT07744724☆ Save

Pirtobrutinib+Pola-R-CHP for Newly Diagnosed Non-GCB DLBCL

Phase II Interventional China

DLBCL - Diffuse Large B Cell Lymphoma · Pirtobrutinib

Recruiting NCT07306832☆ Save

A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)

Phase I Interventional United States, Australia +4

Acute Myeloid Leukemia

Recruiting NCT05564390☆ Save

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Phase II Interventional United States, Canada +1

Acute Myeloid Leukemia · Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm · Acute Myeloid Leukemia Post Cytotoxic Therapy