Recruiting NCT07429448
Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Bupivacain, Normal Saline.
- Who it may be relevant to
- Registry conditions: Appendectomy. Basic parameters: 20 years — 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Pakistan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
To compare the clinical outcomes of intraperitoneal bupivacaine instillation vs placebo as preemptive analgesia in patients undergoing open appendectomy
Interventions
- Drug Bupivacain
Bupivacaine with 0.25% of concentration at the end of the operation intraperitoneally. - Other Normal Saline
10ml of Normal Saline at the end of the operation intraperitoneally.
Primary outcome measures
- Post operative pain [Time frame: 24 hours]
Eligibility criteria
Inclusion criteria
- Patients presenting to the emergency department undergoing open appendectomy.
Exclusion criteria
- Patients undergoing interval appendectomy or having perforated appendix as evident by examination (abdominal tenderness/ fever) and USG findings (presence of abscess, fluid collection, or free air).
- Uncontrolled medical disease (DM: BSL >200mg/dl, HTN: BP >140/90)
- History of chronic kidney or liver disease/ psychiatric illness/ Active peptic ulcer disease (as determined on history and medical records)
- Alcoholics
- History of chronic pain or patients on analgesic medications
- Pregnant females
- History of allergy to bupivacaine/ ketorolac as determined on history
- Children, Adolescents and patients with mental illness.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Supportive care
Study locations
Pakistan · 1 center
- Services Institute of Medical Sciences/ Services Hospital Lahore — Lahore
Identifiers
NCT: NCT07429448 · 14