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Recruiting NCT07424885

BeFlared Versus VBX for FEVAR

No phase Interventional Fenestrated Endovascular Aortic Repair

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Randomization.
Who it may be relevant to
Registry conditions: Fenestrated Endovascular Aortic Repair. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Austria
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

BeFlared FEVAR Stent Graft System© Versus GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis for Fenestrated Endovascular Aortic Repair - Randomized Controlled Unblinded Clinical Trial

Overview

This randomized controlled unblinded trial aimes to compare BeFlared FEVAR Stent Graft System (BeFlared) with GORE® VIABAHN® VBX Balloon Expandable Endoprothesis (VBX) in patients undergoing endovascular aneurysm repair with fenestrated device (FEVAR). Primary objectives: * compare cumulative device time between patients undergoing FEVAR with BeFlared and VBX brindging device; * compare target vessel (TV) instability at early, short-term and midterm follow-up in patients undergoing FEVAR with BeFlared and VBX brindging device. Secondary objectives: \- compare intraoperative TV technical success in patients undergoing FEVAR with BeFlared and VBX bridging device.

Interventions

  • Other Randomization
    Preinterventional randomization of patients to one of two arms - fenestrated endovascular aortic repair with BeFlared FEVAR Stent Graft System© or GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis.

Primary outcome measures

  • Cumulative device time [Time frame: Intraoperative assessment during recruitment period of 2 years]
  • Target vessel (TV) instability at follow-up [Time frame: Early follow-up of first patients enrolled - end of midterm follow-up of last patients enrolled]
Secondary outcome measures (1)
  • Intraoperative target vessel (TV) success [Time frame: Intraoperative assessment during recruitment period of 2 years]

Eligibility criteria

Inclusion criteria

  • written informed consent form signed by the patients before admission to the study;
  • age > 18 years;
  • power of judgement and understanding capability of person;
  • patients with juxtarenal, pararenal, paravisceral AAA, EL Type IA with a previous history of EVAR procedure or TAAA (extent I-IV in accordance with Crawford Classification) undergoing emergency/elective treatment with FEVAR (custom-made or off-the-shelf endograft) at the Division of Vascular Surgery, Department of General Surgery, Medical University of Vienna.

Exclusion criteria

  • age < 18 years;
  • all female patients with a pregnancy possibility (premenopausal)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Other

Study locations

Austria · 1 center
  • Medical University of Vienna, Department of General Surgery, Division of Vascular Surgery — Vienna

Identifiers

NCT: NCT07424885 · 1501/2025

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗