Mastication, Cognition, and Nutritional Status in Multiple Sclerosis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Multiple Sclerosis. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Investigation of the Relationship Between Chewing Function and Cognitive Functions, Disease Severity, and Nutritional Status in Individuals With Multiple Sclerosis
Overview
The aim of this study is to investigate the relationship between chewing function and cognitive functions, disease severity, and nutritional status in individuals diagnosed with Multiple Sclerosis
Primary outcome measures
- Expanded Disability Status Scale (EDSS) [Time frame: Baseline]
- Montreal Cognitive Assessment (MoCA) [Time frame: Baseline]
- Turkish version of the Eating Assessment Scale (T-EAT-10) [Time frame: Baseline]
- Dysphagia in Multiple Sclerosis (DYMUS) [Time frame: Baseline]
- Test of Masticating and Swallowing Solids (TOMASS) [Time frame: Baseline]
- Mini Nutritional Assessment Short Form (MNA) [Time frame: Baseline]
Eligibility criteria
Inclusion criteria
- Being 18 years of age or older
Exclusion criteria
- Having a neurological or systemic disease other than Multiple Sclerosis that may affect chewing function
- Inability to provide adequate communication or cooperation due to psychiatric disorders
- Not being diagnosed with Multiple Sclerosis
- Not volunteering to participate in the study
- Presence of severe problems preventing questionnaire administration (visual and/or hearing impairments)
- History or presence of psychiatric and/or other neurological disorders
- Presence of severe neurological findings that may negatively affect cognitive performance (e.g., severe optic neuritis)
- Use of medications affecting cognitive functions
- Alcohol or substance use
- Having experienced a relapse within the last month
- Having received corticosteroid treatment within the last month
- History of stroke, head and neck cancer, or rheumatic diseases that may affect swallowing and chewing performance
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07411924 · 2025/283