Recruiting NCT07388992

Investigating Specific Gait Patterns in Individuals Living With Multiple Sclerosis

— Observational Multiple Sclerosis Healthy Adult

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied: This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to: Registry conditions: Multiple Sclerosis, Healthy Adult. Basic parameters: 18 years — 65 years · All.
What needs checking: Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place: France
Next step: Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

The study aims to investigate specific ambulation patterns characteristic of the quality of gait in people with MS (pwMS)

description of ambulation pattern in controlled environment in people living with multiple sclerosis (pwMS) with different disease severities [Time frame: enrollment]

For people living with multiple sclerosis (pwMS):

Age at inclusion between =18 and =65 years old
Signed informed consent and ability to comply with study and follow-up.
Confirmed MS diagnosis according to McDonald criteria (2017)
Expanded Disability Status Scale EDSS = 6
Stable treatment for 2 months before inclusion (for both disease modifying and symptomatic therapies)
Ability and willingness to participate in and comply with all study procedures defined in the protocol
Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category

For Healthy volunteers :

Age at inclusion between =18 and =65 years old
Signed informed consent and ability to comply with study and follow-up.
Ability and willingness to participate in and comply with all study procedures defined in the protocol
Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category

For pwMS:

Participants with a relapse within the past 3 months before the inclusion
Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator
Past or present pathology other than MS or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator
Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent.

For healthy volunteers (HV):

Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator
Past or present pathology or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator
Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

France · 1 center

NCT: NCT07388992 · PR5030-119 · 2025-A02511-48