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Not yet recruiting NCT07370935

Trunk Stability, Balance, and Fatigue in Minimally to Moderately Disabled People With Multiple Sclerosis

— Observational Multiple Sclerosis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Measurements.
Who it may be relevant to
Registry conditions: Multiple Sclerosis. Basic parameters: 18 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

The Relationship Between Trunk Stability, Balance, Mobility, Upper Limb Performance, and Fatigue in Minimally to Moderately Disabled People With Multiple Sclerosis

Overview

The goal of this observational study is to investigate the relationship between trunk stability and balance, mobility, upper limb performance, and fatigue in people with multiple sclerosis (MS) with minimal to moderate disability levels. The main questions it aims to answer are: 1. Is trunk stability associated with balance, mobility, upper limb performance, and fatigue in people with multiple sclerosis with minimal to moderate disability? 2. Do balance, mobility, upper limb performance, and fatigue differ between minimally and moderately disabled people with multiple sclerosis? Participants with a diagnosis of multiple sclerosis and Expanded Disability Status Scale (EDSS) scores ≤2 (minimally disabled) and 2.5-4 (moderately disabled) will be included in the study. Participants will undergo standardized clinical assessments to evaluate trunk stability, balance, mobility, upper limb performance, and fatigue during a single assessment session. No intervention will be applied as part of the study, and all measurements will reflect participants' current functional status.

Interventions

  • Other Measurements
    No intervention. Participants will be assessed observationally for trunk stability, balance, mobility, upper limb performance, and fatigue using standardized clinical tests.

Primary outcome measures

  • The Prone Bridge Test [Time frame: Single assessment at the time of enrollment]
  • The Side-bridge Test [Time frame: Single assessment at the time of enrollment]
  • The Trunk Flexor Test [Time frame: Single assessment at the time of enrollment]
  • The Biering-Sorensen Test [Time frame: Single assessment at the time of enrollment]
  • The Sit-ups Test [Time frame: Single assessment at the time of enrollment]
  • The Modified Push-ups Test [Time frame: Single assessment at the time of enrollment]
  • The Postural Stability Test [Time frame: Single assessment at the time of enrollment]
  • The Limits of Stability Test [Time frame: Single assessment at the time of enrollment]
  • The Modified Sensory Organization Test [Time frame: Single assessment at the time of enrollment]
  • The Activities-specific Balance Confidence Scale [Time frame: Single assessment at the time of enrollment]
Secondary outcome measures (3)
  • The Nine-Hole Peg Test [Time frame: Single assessment at the time of enrollment]
  • The Fatigue Severity Scale [Time frame: Single assessment at the time of enrollment]
  • The Fatigue Impact Scale [Time frame: Single assessment at the time of enrollment]

Eligibility criteria

Inclusion criteria

  • The diagnosis of multiple sclerosis was confirmed by a neurologist.
  • Expanded Disability Status Scale (EDSS) score between 0 and 4
  • Age between 18 and 65 years
  • Accepting participation in the study voluntarily

Exclusion criteria

  • An MS attack within the last three months
  • Pregnancy
  • Presence of cardiovascular, pulmonary, or orthopedic conditions that would prevent participation in exercise
  • A disease that can affect the immune system, such as infection or cancer
  • Additional neurological disease

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Other

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07370935 · 25.12

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗