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Recruiting NCT07335211

Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Phase III Interventional Primary Open Angle Glaucoma (POAG) Ocular Hypertension

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: HUC3-637, HUC3-637-R.
Who it may be relevant to
Registry conditions: Primary Open Angle Glaucoma (POAG), Ocular Hypertension. Basic parameters: from 19 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
South Korea
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

A Multicenter, Randomized, Single-blind, Active Controlled, Phase III Clinical Trial to Evaluate the Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension

Overview

A multicenter, randomized, single-blind, active controlled, phase III clinical trial to evaluate the efficacy and safety of HUC3-637 in patients with primary open angle glaucoma or ocular hypertension

Interventions

  • Drug HUC3-637
    Ophthalmic solution instilled directly into the eye (topical ocular administration)
  • Drug HUC3-637-R
    Ophthalmic solution instilled directly into the eye (topical ocular administration)

Primary outcome measures

  • Mean change in diurnal IOP [Time frame: 12 week]

Eligibility criteria

Inclusion criteria

  • Adults aged 19 years and older
  • Participants diagnosed with POAG or OH
  • Have fully explained and understood the study and have voluntarily given written informed consent.

Exclusion criteria

  • Acute or chronic angle-closure glaucoma
  • Congenital glaucoma, secondary glaucoma (open-angle glaucoma)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

South Korea · 1 center
  • Kangbuk Samsung Hospital — Seoul

Identifiers

NCT: NCT07335211 · HUC3-637

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗