The Cold Ischemia Robot-assisted Partial Nephrectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Cold ischemia robot-assisted partial nephrectomy, Warm ischemia robot-assisted partial nephrectomy.
- Who it may be relevant to
- Registry conditions: Renal Cell Carcinoma, Renal Function Abnormal. Basic parameters: 18 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Impact of Cold Ischemia on Recovery From Ischemia After Robot-assisted Partial Nephrectomy: A Randomized Controlled Clinical Study
Overview
To establish evidence that cold ischemia, achieved through the use of ice slush, can improve the recovery from ischemia on the operated kidney in patients undergoing robot-assisted partial nephrectomy.
Detailed description
Randomly dividing the study cohorts into two groups. One group undergoing cold ischemia partial nephrectomy and the other undergoing warm ischemia partial nephrectomy. Comparing the short-term renal function recovery between the two groups.
Interventions
- Procedure Cold ischemia robot-assisted partial nephrectomy
During the surgical procedure, employing ice to achieve local hypothermia in the kidneys. - Procedure Warm ischemia robot-assisted partial nephrectomy
Not applying local hypothermia to the kidneys during the surgical procedure
Primary outcome measures
- Recovery from ischemia [Time frame: 1-12 months after surgery]
Secondary outcome measures (3)
- surgical duration [Time frame: Intraoperative]
- surgical complications [Time frame: 1-12 months after surgery]
- The extent of decline in the long-term GFR (month13-24) on the operated kidney compared to the new baseline GFR(months 1-12). [Time frame: up to 2 years after surgery]
Eligibility criteria
Inclusion criteria
\- 18 to 80 years old; 2. Intending to perform robot-assisted partial nephrectomy
Exclusion criteria
- Anesthesiologist assessment: Patient unsuitable for general anesthesia;
- Having severe cardiovascular and cerebrovascular diseases;
- horseshoe kidney;
- pregnant women
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
China · 1 center
- 651 Dongfeng Road East, Yuexiu District, Guangzhou, P.R. China Sun Yat-sen University Canc — Guangzhou
Identifiers
NCT: NCT07326280 · SL-B2022-518-03