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Recruiting NCT07293338

Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated Cardiomyopathy

— Observational Dilated Cardiomyopathy (DCM)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: coronary angiography.
Who it may be relevant to
Registry conditions: Dilated Cardiomyopathy (DCM). Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The goal of this observational study is to learn about the long-term prognostic of coronary microvascular dysfuction in Patients with Dilated Cardiomyopathy. The main question it aims to answer is: Does the coronary microvascular dysfunction impact the outcomes in Patients with Dilated Cardiomyopathy.

Interventions

  • Procedure coronary angiography
    Patients should undergo coronary angiography to confirm the absence of significant coronary stenosis. Angio-IMR was calculated based on the angiography.

Primary outcome measures

  • Major adverse cardiac events [Time frame: At 5-year follow-up]

Eligibility criteria

Inclusion criteria

  • Dilated cardiomyopathy comfirmed by echocardiography: LVDd > 55 mm in men or > 50 mm in women.
  • Clinically evident congestive heart failure: Compatible symptoms and signs, and BNP ≥ 35 pg/mL or NT-proBNP ≥ 125 pg/mL, and LV systolic dysfunction defined by LVEF < 45 %.
  • Coronary angiography showing stenosis ≤ 50 % in all major epicardial vessels.

Exclusion criteria

  • Patients with coronary artery disease, hypertensive heart disease, rheumatic valvular heart disease, myocarditis, and other secondary cardiomyopathies.
  • poor angiographic image quality

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • The second affiliated hospital of Zhejiang University School of Medicine — Hangzhou

Identifiers

NCT: NCT07293338 · 2025-0971

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗