Identification of Factors Related to UI in Patients With MS and EMG Assessment of PFM Activity
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Multiple Sclerosis. Basic parameters: 30 years — 50 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Identification of Factors Related to Urinary Incontinence in Patients With Multiple Sclerosis and Electromyographic Assessment of Pelvic Floor Muscle Activity: A Cross-Sectional Study
Overview
The study aimed to explore the link between urinary incontinence (UI) severity in patients with multiple sclerosis (PwMS), electromyography (EMG) findings, and other relevant factors.
Detailed description
The study will consist of a cross-sectional observational analysis involving a cohort of 47 PwMS. The assessment will be employed various instruments, including the Expanded Disability Status Scale (EDSS), Neurogenic Bladder Symptom Score (NBSS), International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF), Incontinence Impact Questionnaire (IIQ-7), International Physical Activity Questionnaire (IPAQ), Fatigue Severity Scale (FSS), EMG.
Primary outcome measures
- Expanded disability status scale (EDSS) [Time frame: Single assessment at enrollment]
- Neurogenic Bladder Symptom Score (NBSS) [Time frame: Single assessment at enrollment]
- International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) [Time frame: Single assessment at enrollment]
- Incontinence Impact Questionnaire (IIQ-7) [Time frame: Single assessment at enrollment]
- Pelvic Floor Muscle Activity [Time frame: Single assessment at enrollment]
- International Physical Activity Questionnaire (IPAQ) [Time frame: Single assessment at enrollment]
- Fatigue severity scale (FSS) [Time frame: Single assessment at enrollment]
Eligibility criteria
Inclusion criteria
- having an MS diagnosis according to the 2017 revised McDonald criteria,
- experiencing symptoms of UI as defined by the International Continence Society (ICS),
- having an EDSS score below 6.5,
- PwMS with no communication issues.
Exclusion criteria
- PwMS who did not give consent to participate,
- those with medication changes in the past 6 months,
- pregnant PwMS,
- recent vaginal or caesarean deliveries within 6 months,
- pelvic organ prolapse,
- urinary tract infection,
- recent attack history in the past month.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Other
Study locations
Turkey (Türkiye) · 1 center
- Prof. Dr. Cemil Taşçıoğlu City Hospital — Istanbul
Publications
- Zecca C, Riccitelli GC, Disanto G, Singh A, Digesu GA, Panicari L, Puccini F, Mattioli M, Tubaro A, Gobbi C. Urinary incontinence in multiple sclerosis: prevalence, severity and impact on patients' quality of life. Eur J Neurol. 2016 Jul;23(7):1228-34. doi: 10.1111/ene.13010. Epub 2016 Apr 27. PMID 27120000
- Tornic J, Panicker JN. The Management of Lower Urinary Tract Dysfunction in Multiple Sclerosis. Curr Neurol Neurosci Rep. 2018 Jun 28;18(8):54. doi: 10.1007/s11910-018-0857-z. PMID 29956001
- Afshari P, Abedi P, Majdinasab N, Tafakh S, Haghighizadeh M. Strengths of pelvic floor muscles in women with multiple sclerosis and its relationship with urinary incontinence and quality of life. Front Neurol. 2025 Jan 13;15:1514157. doi: 10.3389/fneur.2024.1514157. eCollection 2024. PMID 39871990
Identifiers
NCT: NCT07236684 · EMG MS