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Not yet recruiting NCT07233200

Dermabrasion for Free Flap Aesthetic Enhancement

No phase Interventional Scar Conditions and Fibrosis of Skin

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Dermabrasion.
Who it may be relevant to
Registry conditions: Scar Conditions and Fibrosis of Skin. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Serial Dermabrasion for Aesthetic Enhancement of Free Flap Skin Paddles and Donor Sites: A Prospective Split-Flap/Scar Controlled Study

Overview

The purpose of this study is to evaluate the aesthetic benefit and safety of serial dermabrasion for free flap skin paddles and donor site scars in head and neck reconstruction.

Interventions

  • Device Dermabrasion
    This is the only intervention. Free flap scars will be split and half treated, half untreated then outcomes graded.

Primary outcome measures

  • Aesthetic grading of treated area compared to untreated [Time frame: 1, 3, and 6 months post-treatment]

Eligibility criteria

Inclusion criteria

  • Adults aged 18 years or older.
  • History of successful free flap reconstruction with a cutaneous skin paddle in the head and neck region.
  • Patients with benign (eg. osteoradionecrosis, trauma) or malignant (eg. squamous cell carcinoma) diagnoses requiring free flap reconstruction.
  • Benign free flap patients must be a minimum 3 months post-operative to ensure flap maturity. Malignant free flap patients must be a minimum of 3 months post-operative or post-radiation with no further cancer treatment (eg. radiation, surgery, chemotherapy) planned at that time.
  • Flap skin paddle must be of sufficient size and external to allow for split-treatment design (minimum 4 cm in diameter). Donor site scar must also be sufficient size (minimum 6 cm in length)
  • Patients must have ability to provide informed consent.
  • Willingness and ability to comply with the treatment and follow-up schedule.

Exclusion criteria

  • Inability to give informed consent.
  • Evidence of active flap or radiation skin complications (e.g., infection, partial necrosis, wound breakdown).
  • Completion of head and neck radiation therapy within 3 months of first dermabrasion treatment date.
  • Uncontrolled diabetes mellitus (HbA1c > 8.0%).
  • Current antibiotic use or known immunocompromised state.
  • History of keloid formation or hypertrophic scarring.
  • Fitzpatrick skin type VI or higher (due to increased risk of pigmentary changes).
  • Use of isotretinoin medication within the past 3 month (known to induce photosensitivity).
  • Current use of blood thinners that cannot be safely paused.
  • Known photosensitivity disorders.
  • Active malignancy requiring ongoing treatment.
  • Inability or unwillingness to avoid sun exposure during the treatment period.
  • Inability to perform or adhere to prescribed wound care.
  • Inability or unwillingness to attend follow-up visits.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07233200 · 00027645

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗