Global Overweight and oBesE (GLOBE) Patient Registry, Development and Implementation of Disease-specific: Severity, Quality of Life and Cost Instruments.
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Overweight (BMI > 25), Obesity & Overweight. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United Kingdom
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
We are conducting this study to develop a disease-specific instrument, a quality of life instrument and a comprehensive list of costs associated with overweight and obesity.
Detailed description
Despite evidence on the burden of BMI \>25, few disease-specific instruments comprehensively capture its multidimensional impact. Existing frameworks often target obesity (BMI ≥30) or patients on pharmacological or surgical therapy. Overweight and extremely obese populations are underrepresented, and economic and psychosocial dimensions are rarely integrated into severity staging.
This study, therefore, aims to systematically evaluate symptoms, comorbidities, HRQoL, and costs across the full spectrum of individuals with BMI \>25, excluding those on GLP-1 therapy. Integrating clinician and patient perspectives will support the development of more inclusive severity measures and inform early intervention strategies.
Primary outcome measures
- Development of a Disease-Specific Questionnaire [Time frame: 2 months]
Secondary outcome measures (1)
- Quality of Life Instrument [Time frame: 2 months]
Eligibility criteria
Inclusion criteria
- Patient group
- Patient is aged ≥18 years at the time of survey completion.
- Patient has a BMI over 25 (self-reported)
- Patient is willing to participate in all study activities.
- Patient is able to read, write, and converse in English.
- Healthcare professional participant must meet the following criteria for inclusion in the study:
- HCP is aged ≥18 years at the time of survey completion.
- HCP is suitably qualified and involved in the healthcare management of patients with a BMI over 25
- HCP is willing to participate in all study activities.
- HCP is able to read, write, and converse in English.
Exclusion criteria
A participant who meets any of the following criteria will be excluded from the study:
- Participants do not have the cognitive capacity to provide informed consent.
- Participants with severe co-morbidity that might affect study participation.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
United Kingdom · 1 center
- Online recruitment — Milton Keynes
Identifiers
NCT: NCT07229027 · MED 63