Sexual Dysfunction in Women With Multiple Sclerosis (MS)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Fatigue in Multiple Sclerosis, Sexual Disfunction. Basic parameters: 25 years — 50 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Sexual Dysfunction Prevalence and Its Relationship With Various Factors in Women With Multiple Sclerosis
Overview
Sexual dysfunction in women with multiple sclerosis (MS) is an important yet often overlooked problem. The primary objective of this study is to investigate the prevalence of sexual dysfunction in female patients diagnosed with MS. The secondary objective is to evaluate the relationship between sexual dysfunction and fatigue, depression, anxiety, overactive bladder symptoms, and cognitive dysfunction. For this purpose, the following validated instruments will be used: the Female Sexual Function Index (FSFI) to assess sexual dysfunction, the Brief International Cognitive Assessment for MS (BICAMS) to evaluate cognitive function, the Hospital Anxiety and Depression Scale (HADS) to assess depression and anxiety, the Fatigue Severity Scale (FSS) to measure fatigue, and the Overactive Bladder Questionnaire (OAB-V8) to evaluate overactive bladder symptoms.
Primary outcome measures
- Prevalence of sexual dysfunction in female patients with multiple sclerosis [Time frame: At enrollment (Baseline, cross-sectional assessment)]
Secondary outcome measures (1)
- Association between sexual dysfunction and cognitive dysfunction, fatigue, depression, anxiety, and overactive bladder symptoms [Time frame: At enrollment (Baseline, cross-sectional assessment)]
Eligibility criteria
Inclusion criteria
- Female patients aged 25-50 years
- Literate and able to comprehend written and spoken instructions
- Diagnosed with relapsing-remitting form of multiple sclerosis
- Having a continuous/regular sexual partner
- Expanded Disability Status Scale (EDSS) score ≤ 5
- At least 3 months since the last relapse
- Sexually active within the past 3 months
- Spasticity level < grade 2 according to the Modified Ashworth Scale
Exclusion criteria
- Pregnancy
- Illiteracy or inability to understand spoken or written instructions
- Absence of a continuous/regular sexual partner
- Expanded Disability Status Scale (EDSS) score > 5
- Not sexually active within the past 3 months
- Spasticity level ≥ grade 2 according to the Modified Ashworth Scale
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 1 center
- Ege University Faculty of Medicine, Department of Neurology — Izmir
Identifiers
NCT: NCT07193823 · 24-5.1T/1