Predictive Value of CEA and ctDNA in Lung Cancer Recurrence
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Lung Carcinoma. Basic parameters: 15 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Predictive Value of CEA and ctDNA for Postoperative Recurrence in Patients With High CEA Sensitivity Lung Cancer
Overview
The study aims to investigate the predictive value of CEA levels for postoperative recurrence in the highly sensitive CEA lung cancer patients and to explore whether the dynamic changes of postoperative CEA and MRD in this population are related.This study was carried out to accurately predict the recurrence time, save the time and cost of changing the intervention strategy, and provide more personalized treatment for patients.
Detailed description
This study will collect two groups of cohorts: prospective and retrospective.
Primary outcome measures
- Postoperative tumor recurrence or progression [Time frame: 2 years]
Eligibility criteria
Inclusion criteria
- Preoperative CEA > 5mg/l
- MRD testing was conducted before the operation
- The primary lesion was resected through surgery
- There should be at least two CEA and MRD follow-up tests within 2 years after the operation
- Postoperative pathology confirmed it as a malignant lung tumor
Exclusion criteria
- Those without available imaging records
- Patients with a history of malignant tumors within the past five years
- Patients with secondary lung cancer
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07170046 · KY2025-310