Microplastic Analysis in Pediatric Inflammatory Bowel Disease
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Environmental microplastic exposure.
- Who it may be relevant to
- Registry conditions: Crohn Disease, Pediatric Inflammatory Bowel Diseases, Ulcerative Colitis (UC), Inflammatory Bowel Disease (IBD). Basic parameters: up to 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Poland
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Analysis of Microplastics in Pediatric Inflammatory Bowel Disease Using Raman Spectroscopy: A Multi-Matrix Study
Overview
The goal of this observational study is to measure and compare the presence of microplastics in children with inflammatory bowel disease (IBD) and children without IBD. The main questions it aims to answer are: Are microplastics detectable in different biological samples from children? Are there differences in microplastic burden between children with and without IBD? Researchers will collect biological samples including: intestinal tissue (from routine endoscopy), stool, urine, blood. Raman spectroscopy will be used to detect and characterize microplastics in each sample type. Participants will not receive any medication or intervention as part of this study. All samples will be collected during standard clinical procedures.
Interventions
- Other Environmental microplastic exposure
Exposure to environmental microplastics measured by their presence in intestinal tissue, blood, urine, and stool using Raman spectroscopy. This study does not assign any exposure or treatment; it investigates the existing presence of microplastics as an environmental factor of interest.
Primary outcome measures
- Presence and concentration of microplastics in intestinal tissue samples [Time frame: Day of endoscopy (Baseline)]
Secondary outcome measures (1)
- Comparison of microplastic burden between children with IBD and controls [Time frame: Baseline (Day of sample collection)]
Eligibility criteria
Inclusion criteria
- Age <18 years
- Undergoing clinically indicated gastrointestinal endoscopy
- For IBD group: confirmed diagnosis of Crohn's disease or ulcerative colitis
- For control group: no current or past diagnosis of IBD
Exclusion criteria
- Age 18 years or older
- Lack of informed consent from legal guardian
- Lack of written assent from the participant if age ≥13 years
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-control
Study locations
Poland · 1 center
- Medical University of Gdańsk, Department of Pediatrics, Gastroenterology, Allergolgy and N — Gdansk
Identifiers
NCT: NCT07141238 · MAP-IBD-2025