Survey of Patients Who Received Fertility Preservation Counseling and Underwent Testicular Tissue Cryopreservation Prior to Gonadotoxic Treatment During Childhood or Peripuberty
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Survey using a questionnaire..
- Who it may be relevant to
- Registry conditions: Satisfaction Survey, Fertility Perservation. Basic parameters: from 18 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Belgium
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Survey of Patients Who Underwent Testicular Tissue Cryopreservation for Fertility Preservation Prior to Gonadotoxic Therapy in Childhood or Peripuberty
Overview
Chemotherapy and radiotherapy can lead to spermatogonial stem cell depletion in pre- and peripubertal boys, potentially resulting in infertility during adulthood A testicular biopsy is considered a safe procedure performed in children prior to gonadotoxic treatment as part of a fertility preservation strategy. At the time of the procedure, parental involvement is essential-both in their role as legal guardians and due to the limited cognitive capacity of young boys to fully comprehend fertility preservation counseling. Long-term follow-up is necessary to evaluate the impact on fertility outcomes, psychological well-being, and overall satisfaction. The aim of this survey is to assess the perceived impact of fertility preservation counseling and the physical and emotional effects of undergoing testicular biopsy in this population, with the goal of identifying opportunities to improve patient experience and clinical care for future patients.
Interventions
- Other Survey using a questionnaire.
A monocentric experimental study conducted as a survey, including patients enrolled in our fertility preservation program between May 2005 and May 2020. Participants were asked about their current reproductive health status, their experience with the fertility preservation process, and their overall satisfaction with the care they received.
Primary outcome measures
- The impact on quality of life of fertility preservation during childhood or adolescence. [Time frame: From the start of the program in may 2005 and the last patient enrolled in may 2020]
Eligibility criteria
Inclusion criteria
- All patients who have participated in the fertility preservation program aged 18 years old and above
Exclusion criteria
- Deceased patients. Patients undergoing treatment for disease relapse. Patients suffering from a documented mental disorder.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Health services research
Study locations
Belgium · 1 center
- Cliniques universitaires Saint-Luc — Brussels
Identifiers
NCT: NCT07140549 · 2023/14JUI/263