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Recruiting NCT07047807

PDAC-PATHWAYS: A Digital Informational and Supportive Care App for Patients Initiating Neoadjuvant Therapy for Pancreatic Ductal Adenocarcinoma

No phase Interventional PDAC - Pancreatic Ductal Adenocarcinoma

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: PDAC-PATHWAYS, Usual Care.
Who it may be relevant to
Registry conditions: PDAC - Pancreatic Ductal Adenocarcinoma. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

This study aims to refine and pilot test PDAC-PATHWAYS, a digital informational and supportive care app for patients who are initiating neoadjuvant therapy for pancreatic ductal adenocarcinoma (PDAC).

Detailed description

There are two parts of this study. Study Part 1 is an open pilot study to refine PDAC-PATHWAYS prior to larger-scale testing in a randomized controlled trial (RCT) setting. Study Part 1 is purely descriptive, as the investigators will use the data to refine PDAC-PATHWAYS before proceeding to Study Part 2.

Study Part 2 is a pilot RCT to assess the feasibility and acceptability of conducting a randomized trial of PDAC-PATHWAYS versus usual care. Participants will complete a baseline survey and then be randomized to PDAC-PATHWAYS versus usual care. This record reflects the clinical trial component (Study Part 2), as feasibility and acceptability outcomes will be collected for this phase only.

Interventions

  • Behavioral PDAC-PATHWAYS
    A digital app for patients initiating neoadjuvant therapy for PDAC
  • Other Usual Care
    Routine treatment

Primary outcome measures

  • Feasibility: Enrollment rate [Time frame: 10 weeks]
  • Feasibility: intervention completion rate [Time frame: 10 weeks]
Secondary outcome measures (1)
  • Acceptability [Time frame: 10 weeks]

Eligibility criteria

Inclusion criteria

  • Age≥18 years
  • Within 8 weeks of a documented decision to pursue neoadjuvant therapy for newly diagnosed, non-metastatic PDAC
  • Able to comprehend and speak English

Exclusion criteria

  • Comorbid health condition that would interfere with study participation, as identified by the cancer care team

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Supportive care

Study locations

United States · 1 center
  • Massachusetts General Hospital — Boston

Identifiers

NCT: NCT07047807 · 25-350

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗