Recruiting NCT07014592
Characterization and Analysis of Evoked Cortical Responses in Participants With Medication-intractable Epilepsy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: stimulating probes and electrodes.
- Who it may be relevant to
- Registry conditions: Intractable Epilepsy. Basic parameters: 22 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The goal of this project is to study how the brain reacts to a small electrical signal. Researchers will be using a novel combination of recording electrodes. The researchers will measure the brain response from these electrodes.
Interventions
- Device stimulating probes and electrodes
Subdural electrodes and/or ball tip probes will be used intraoperatively to provide electrical stimulation to the brain.
Primary outcome measures
- Characterization of time-frequency data [Time frame: During a 20 minute research phase of a clinically indicated surgery]
- Characterization of local field responses (LFPs) [Time frame: During a 20 minute research phase of a clinically indicated surgery]
Eligibility criteria
Inclusion criteria
- Patients with medication intractable epilepsy who are recommended to undergo brain surgery to remove a "seizure" focus
- Can provide informed consent for the study and willing to participate
Exclusion criteria
- Presence of a permanent electronic implant
- Any chronic medical conditions that prevent safe placement of electrodes
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Basic science
Study locations
United States · 1 center
- University of Michigan — Ann Arbor
Identifiers
NCT: NCT07014592 · HUM00258281