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Not yet recruiting NCT07013435

A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship

No phase Interventional Lymphoma

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Health Education Program, SMART3RP-Lymphoma.
Who it may be relevant to
Registry conditions: Lymphoma. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Thriving Beyond Treatment: A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship.

Overview

The goal of this trial is to learn if a resilience intervention can lead to improvements in lymphoma survivors' quality of life.

Detailed description

The Stress Management and Relaxation Response Resiliency Program for lymphoma survivors (SMART3RP-Lymphoma) was adapted by researchers at the MGH. This group program seeks to buffer stress and promote psychological resiliency and physical well-being through a variety of mind-body approaches, such as imagery, relaxation, and yoga, cognitive behavioral strategies, and positive psychology tools.

The main questions it aims to answer are:

* Will survivors randomized to SMART3RP-Lymphoma demonstrate greater improvements in quality of life when compared to survivors randomized to a Health Education Program? * Will improvements in resiliency lead to improvements in quality of life?

To answer these questions, researchers will compare a resilience intervention tailored to the needs of lymphoma survivors (SMART3RP-Lymphoma) to a Health Education Program to see how they affect quality of life of lymphoma survivors.

Participants will:

* Fill out 4 surveys across 12 months * Participate in 8 weekly, virtual group sessions * Submit hair cortisol samples

Interventions

  • Other Health Education Program
    8 weekly sessions that include education on the co-occurrence of mental and physical problems, goal setting for health behavior change, and self-monitoring. Each session includes basic didactic information, interactive application of the information, and open discussion of didactic material.
  • Other SMART3RP-Lymphoma
    The SMART3RP-lymphoma is a group program that, through a variety of mind-body approaches, such as imagery, relaxation, and yoga, seeks to buffer stress and promote psychological resiliency and physical well-being.

Primary outcome measures

  • Quality of Life (QoL): Change in PROMIS-29 [Time frame: From enrollment to 6 month follow up]
Secondary outcome measures (1)
  • Resilience: Change in Scores on the Current Experiences Scale (CES) [Time frame: Enrollment to 3 month follow up]

Eligibility criteria

Inclusion criteria

  • English or Spanish speaking adults (18+ at time of enrollment)
  • Within 2 years of completing active, curative treatment for lymphoma (includes surgery, chemotherapy, immunotherapy, radiation therapy, or other)

Exclusion criteria

  • Active psychiatric or cognitive comorbidity as determined by the site PI or treating clinician

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Supportive care

Study locations

United States · 1 center
  • Mass General Hospital — Boston

Identifiers

NCT: NCT07013435 · 25-204

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗