Electrical Impedance Tomography-Based Prognostic Model for ARDS
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Not applicable- observational study.
- Who it may be relevant to
- Registry conditions: Acute Respiratory Distress Syndrome (ARDS), Ventilator-induced Lung Injury. Basic parameters: 18 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Electrical Impedance Tomography-Based Prognostic Model for ARDS: A Multicenter, Prospective, Observational Study
Overview
This multicenter, prospective, observational study aims to develop and validate an EIT-based prognostic model for ARDS. By focusing on the pathophysiological characteristics of ARDS and the causes of ventilator-induced lung injury, the investigators intend to establish a prognostic model that reveals lung injury and heterogeneity, enabling risk stratification and guiding individualized treatment.
Interventions
- Other Not applicable- observational study
Not applicable- observational study
Primary outcome measures
- 28-day mortality rate [Time frame: From date of study enrollment (Day 0) until Day 28]
Secondary outcome measures (7)
- ICU mortality rate [Time frame: From ICU admission to discharge, up to 24 weeks]
- 60-day all-cause mortality rate [Time frame: 60 days post-enrollment]
- 90-day all-cause mortality rate [Time frame: 90 days post-enrollment]
- Duration of mechanical ventilation (days) [Time frame: From intubation to successful extubation, up to 28 days]
- Ventilator-free days (VFDs) at 28 days [Time frame: 28 days post-enrollment]
- ICU length of stay (days) [Time frame: From ICU admission to discharge, up to 24 weeks]
- Hospital length of stay [Time frame: From hospital admission to discharge, up to 24 weeks]
Eligibility criteria
Inclusion criteria
- Meet the new 2023 ARDS global definition;
- Age 18-80 years
Exclusion criteria
- Expected death within 24 hours of screening;
- Metastatic cancer (active malignancy with distant metastases);
- Severe psychiatric disorders;
- Pregnancy or postpartum status;
- Pneumothorax or moderate to large pleural effusion without adequate drainage;
- Chronic respiratory failure;
- Patients with pulmonary embolism or pulmonary hypertension;
- Heart failure patients: EF <50% or NYHA class III or IV;
- Patient/family refusal to participate;
- Participation in another interventional trial within 3 months prior to enrollment
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 4 centers
- Department of Critical Care Medicine, Guangdong Provincial People's Hospital — Guangzhou
- Department of Critical Care Medicine, Renmin Hospital of Wuhan University — Wuhan
- Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong Uni — Wuhan
- Department of Emergency, Zhongshan Hospital, Fudan University — Shanghai
Identifiers
NCT: NCT06967207 · EIT20250331