Comparison Between Individualized PEEP Ventilation Guided by Driving Pressure and Conventional Lung Protective Strategy in Obese Patients Undergoing Laparoscopic Bariatric Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: lung ultrasound.
- Who it may be relevant to
- Registry conditions: Obese Patients With Bariatric Surgery, Lung Ultrasound Score. Basic parameters: 18 years — 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Comparison Between Individualized PEEP Ventilation Guided by Driving Pressure and Conventional Lung Protective Strategy in Obese Patients Undergoing Laparoscopic Bariatric Surgery: a Prospective Randomized Controlled Trial
Overview
this study to compare the ventilation in obese patients either using Driving pressure ventilation technique or conventional protective lung strategy all by using Lung ultrasound score
Interventions
- Device lung ultrasound
The lung ultrasound score between 0 and 3 (0 = normal A lines, 1 = multiple separated B lines, 2 = coalescing B lines or light beam, 3 = consolidation). The aeration score will be built by the sum of the scores of the 12 segments, with a minimum of 0 and a maximum of 36 according to the aeration loss.
Primary outcome measures
- The change in lung ultrasound score [Time frame: Periprocedural]
Secondary outcome measures (9)
- Lung compliance [Time frame: Periprocedural]
- Hemodynamic parameter as oxygen saturation [Time frame: Periprocedural]
- Hemodynamic parameter as Heart rate [Time frame: Periprocedural]
- Hemodynamic parameter as Mean arterial blood pressure [Time frame: Periprocedural]
- End-tidal carbon dioxide (ETCO2) [Time frame: Periprocedural]
- Plateau Pressure (Pplat) [Time frame: Periprocedural]
- Peak airway pressure (Ppeak) [Time frame: Periprocedural]
- Incidence of early postoperative pulmonary complications [Time frame: At the end of the surgery up to 24 hours after surgery]
- Length of post anesthesia care unit "PACU" stay. [Time frame: At the end of the surgery up to 2 hours after surgery]
Eligibility criteria
Inclusion criteria
- patients who have a BMI 30-40 kg/m2
- American Society of Anesthesiologists (ASA) physical status II or III
- patients aged between 18 and 60 years,
- patients scheduled to undergo laparoscopic bariatric surgeries.
Exclusion criteria
- patients' refusal to participate in the study,
- previous history of thoracic surgery,
- Patients with a history of chest disease (COPD, emphysema, or pneumothorax),
- Patients with abnormal pre-operative chest radiographs, such as pneumonia and pleural effusion,
- Patients with right-side heart failure or impending failure,
- Patients with known hypovolemia, and Patients with increased intracranial pressure.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
Egypt · 1 center
- Tanta university — Tanta
Identifiers
NCT: NCT06950112 · 36265MD302/11/24