Effect of Dual-Task Training and Cognitive Rehabilitation in Individuals With Multiple Sclerosis.
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Dual Task Training, Cognitive Rehabilitation, Conventionel Physiotherapy.
- Who it may be relevant to
- Registry conditions: Multiple Sclerosis. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effects of Dual-Task Training and Cognitive Rehabilitation on Gait, Balance, Fatigue and Cognitive Performance in Individuals With Multiple Sclerosis
Overview
The purpose of this study is to examine the effects of dual-task training and cognitive rehabilitation on gait, balance, fatigue and cognitive performance in individuals with multiple sclerosis.
Detailed description
Multiple sclerosis (MS) is a complex disease characterized by chronic, inflammatory, demyelinating and neurodegenerative processes of the central nervous system (CNS) with heterogeneous clinical symptoms. Balance, gait and cognitive impairment are among the biggest problems in individuals with MS and significantly affect their daily lives.
Dual Task (DT); is the process of performing two tasks that can be performed independently and have different purposes simultaneously. Walking with dual tasks has recently been shown to resemble typical walking performance in daily life, thus providing clinicians with a realistic walking performance measurement in daily life. Although the effects of dual task performance in various neurological diseases have been partially described in the literature, the comparison of dual task training and cognitive rehabilitation on walking, balance, fatigue and cognitive performance has not been made and due to this deficiency in the literature, our study was planned and has originality. The aim of our study is to investigate the effects of dual task training and cognitive rehabilitation on walking, balance, fatigue and cognitive performance in individuals with MS.
Interventions
- Other Dual Task Training
In dual task training, patients will be given cognitive exercises such as counting backwards from 100 by 3, counting the names of cities, girls and boys while walking. - Other Cognitive Rehabilitation
In cognitive rehabilitation, patients will be given paper-and-pencil activities and exercises to find the difference between two pictures. - Other Conventionel Physiotherapy
In conventionel physiotherapy, patients will be given posture exercises for balance and strengthening.
Primary outcome measures
- Dynamic Gait Index (DGI) [Time frame: a year]
Secondary outcome measures (5)
- Timed 25 Food Walk Test (T25FWT) [Time frame: a year]
- The 12-item MS Walking Scale (12-MSWS) [Time frame: a year]
- BICAMS (Brief International Cognitive Assessment for MS) [Time frame: a year]
- Trial Making Test (TMT) [Time frame: a year]
- Modified Fatigue Impact Scale (MFIS) [Time frame: a year]
Eligibility criteria
Inclusion criteria
- Definite MS diagnosis by a neurologist
- Can walk independently
- Expanded Disability Status Scale (EDSS) score below 5
- Has not had an attack in the last 3 months, has been medically stable for 6 months
- Has not received a regular physiotherapy program in the last 6 months volunteer
Exclusion criteria
- Scoring 26 or below on the Montreal Cognitive Assessment Scale (MoCA)
- Having systemic, orthopedic and neurological problems that may affect walking and balance in the assessments
- Having additional psychiatric disorders
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Turkey (Türkiye) · 1 center
- Mersin University — Mersin
Publications
- Ozkul C, Guclu-Gunduz A, Eldemir K, Apaydin Y, Gulsen C, Yazici G, Soke F, Irkec C. Dual-Task Cost and Related Clinical Features in Patients With Multiple Sclerosis. Motor Control. 2021 Jan 12;25(2):211-233. doi: 10.1123/mc.2020-0035. PMID 33440347
- Abasiyanik Z, Kahraman T. Effect of dual-task training on cognitive functions in persons with multiple sclerosis: A systematic review and meta-analysis. Mult Scler Relat Disord. 2022 Jun;62:103801. doi: 10.1016/j.msard.2022.103801. Epub 2022 Apr 10. PMID 35430546
Identifiers
NCT: NCT06949696 · TU-FTR-AK-01