Non-Helium Magnetoencephalography in Pediatric Brain Tumors
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Magnetoencephalography plus Computed Tomography/Magnetic Resonance Imaging.
- Who it may be relevant to
- Registry conditions: Pediatric Brain Tumor. Basic parameters: 3 years — 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Non-Helium Magnetoencephalography for Clinical Management of Pediatric Brain Tumors : An Observational Cohort Study
Overview
This observational study aims to evaluate the effectiveness of magnetoencephalography (MEG) in the preoperative assessment of pediatric brain tumors, particularly in determining the extent of resection, and compare it with computed tomography (CT) and magnetic resonance imaging (MRI). The main questions this study aims to answer are: What is the consistency between MEG and CT/MRI in localizing pediatric brain tumors? What is the clinical efficacy of MEG in determining the extent of resection of pediatric brain tumors preoperatively? Participants will: Undergo both MEG and CT/MRI examinations for preoperative assessment, and the extent of tumor resection will be determined by the comprehensive results of the above examinations. Be followed up with MEG and CT/MRI at 1, 3, and 6 months after surgery, along with neurological and quality-of-life assessments.
Interventions
- Diagnostic test Magnetoencephalography plus Computed Tomography/Magnetic Resonance Imaging
Use Magnetoencephalography and Computed Tomography/Magnetic Resonance Imaging in the preoperative assessment of pediatric brain tumors.
Primary outcome measures
- Consistency in Tumor Localization Between Magnetoencephalography (MEG) and Computed Tomography/Magnetic Resonance Imaging (CT/MRI) (Kappa Coefficient) [Time frame: From enrollment to 12 months after surgery.]
Eligibility criteria
Inclusion criteria
- Age range: 3-18 years old;
- Clinically diagnosed with brain tumor;
- Capable of cooperating with magnetoencephalography evaluation and recording.
Exclusion criteria
- Patients with serious comorbidities or neurological or psychiatric disorders that affect magnetoencephalography examination.
- Patients using drugs that affect central nervous system function;
- Patients who are not suitable for surgical procedures;
- Patients with progressive neurological disorders.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Guangzhou Women and Children's medical center — Guangzhou
Identifiers
NCT: NCT06943742 · 449A01