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Recruiting NCT06882252

Increasing Lean Protein Intake in Preschool-age Children and Assessing Effects on Cognition and Select Health Outcomes

No phase Interventional Diet Modification

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Low glycemic index diet.
Who it may be relevant to
Registry conditions: Diet Modification. Basic parameters: 2 years — 5 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Increasing Lean Protein Intake in Preschool-age Children

Overview

The proposed project addresses the goal of exploring preschooler's ability to recognize changes in feelings of hunger/satiety based on consuming a snack and a meal (lunch/dinner) that are either based on the usual childcare center fare (control) or are based on lean meats (intervention), which will have a lower glycemic index.

Interventions

  • Other Low glycemic index diet
    Replacement of typical meal/snack with lean pork containing meal/snack

Primary outcome measures

  • Glycemic load of diet [Time frame: 6 study days]
  • Hunger/Satiety self-reported on 4-point scale [Time frame: 6 study days]
Secondary outcome measures (6)
  • Blood pressure [Time frame: 60 minutes after the meal.]
  • Blood glucose [Time frame: 6 study days]
  • Executive function: focus and short-term memory [Time frame: 6 study days]
  • Executive function: memory and focus [Time frame: 6 study days]
  • Executive Function: Focus and Concentration [Time frame: 6 study days]
  • Executive Function: Concentration [Time frame: 6 study days]

Eligibility criteria

Inclusion criteria

  • child 2-5 years old

Parent participants:

  • Parents of at least one child aged 2-5 years old
  • Parents can communicate in English.
  • Parents in households who do not have a cultural/ religious reason to abstain from to consuming pork

Exclusion criteria

  • Child participants:
  • Food allergies
  • Taking medication that affects food intake (such as stimulant medications),
  • Children with diabetes or impaired glucose control.
  • Children with digestive disease (such as Crohn's)
  • Dietary/religious preferences that exclude consumption of pork

Parent participants:

\- Dietary/religious preferences that exclude consumption of pork

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Crossover
Masking
Open label
Primary purpose
Other

Study locations

United States · 1 center
  • University of Virginia — Charlottesville

Publications

  • Varley BJ, Nasir RF, Skilton MR, Craig ME, Gow ML. Early Life Determinants of Vascular Structure in Fetuses, Infants, Children, and Adolescents: A Systematic Review and Meta-Analysis. J Pediatr. 2023 Jan;252:101-110.e9. doi: 10.1016/j.jpeds.2022.08.033. Epub 2022 Aug 24. PMID 36029824
  • Mikkila V, Rasanen L, Raitakari OT, Pietinen P, Viikari J. Consistent dietary patterns identified from childhood to adulthood: the cardiovascular risk in Young Finns Study. Br J Nutr. 2005 Jun;93(6):923-31. doi: 10.1079/bjn20051418. PMID 16022763

Identifiers

NCT: NCT06882252 · HSR231601

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗