The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Montreal Cognitive Assessment.
- Who it may be relevant to
- Registry conditions: Neurocognitive Disorder, Robotic Assisted Laparoscopic Radical Prostatectomy, Near Infrared Spectroscopy. Basic parameters: 65 years — 100 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Examining the Effect of Steep Trendelenburg Position on Neurocognitive Functions With MoCA Test in Robotic-assisted Radical Prostatectomy Surgeries.
Overview
The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period. Steep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.
Interventions
- Diagnostic test Montreal Cognitive Assessment
Preoperative and postoperative MoCA test scores
Primary outcome measures
- MoCA [Time frame: preoperatively]
- MoCA [Time frame: day 1]
Secondary outcome measures (1)
- NIRS [Time frame: intraoperatively]
Eligibility criteria
Inclusion criteria
- Age ≥ 65 years
- ASA II-III risk score
- Patients scheduled for robotic radical prostatectomy
- Patients who voluntarily agree to participate
Exclusion criteria
- Age < 65 years
- History of neurological or psychiatric disorders
- Inability to undergo robotic surgery
- Conversion to open prostatectomy during surgery
- Patients who do not consent to participate
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 1 center
- Ankara City Hospital Bilkent — Ankara
Identifiers
NCT: NCT06869304 · TABED2-24-570